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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: O08709




SWISS-2DPAGE:  O08709


O08709


General information about the entry
View entry in simple text format
Entry namePRDX6_MOUSE
Primary accession numberO08709
integrated into SWISS-2DPAGE on June 30, 1999 (release 10)
2D Annotations were last modified onMay 15, 2003 (version 4)
General Annotations were last modified on November 9, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-6; EC=1.11.1.15; AltName: Full=1-Cys peroxiredoxin; Short=1-Cys PRX; AltName: Full=Acidic calcium-independent phospholipase A2; Short=aiPLA2; EC=3.1.1.-; AltName: Full=Antioxidant protein 2; AltName: Full=Non-selenium glutathione peroxidase; Short=NSGPx; EC=1.11.1.9;.
Gene nameName=Prdx6
Synonyms=Aop2, Ltw4, Prdx5
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=6.19; Mw=26097

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=6.26; Mw=26252  [identification data]
pI=5.90; Mw=26197  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=6.23; Mw=26047  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=6.16; Mw=28186  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
COMPLUYEAST-2DPAGEO08709; PRDX6_MOUSE.
REPRODUCTION-2DPAGEO08709; O08709.
UCD-2DPAGEO08709; PRDX6_MOUSE.
UniProtKB/Swiss-ProtO08709; PRDX6_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRDX6_MOUSE
Primary accession numberO08709
Secondary accession number(s) Q91WT2 Q9QWP4 Q9QWW0
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-6; EC=1.11.1.15; AltName: Full=1-Cys peroxiredoxin; Short=1-Cys PRX; AltName: Full=Acidic calcium-independent phospholipase A2; Short=aiPLA2; EC=3.1.1.-; AltName: Full=Antioxidant protein 2; AltName: Full=Non-selenium glutathione peroxidase; Short=NSGPx; EC=1.11.1.9;
Gene nameName=Prdx6
Synonyms=Aop2, Ltw4, Prdx5
Encoded onName=Prdx6; Synonyms=Aop2, Ltw4, Prdx5
KeywordsAcetylation; Antioxidant; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Direct protein sequencing; Disulfide bond; Hydrolase; Lipid degradation; Lysosome; Multifunctional enzyme; Oxidoreductase; Peroxidase; Phosphoprotein; Redox-active center; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF004670; AAC53277.1; -; mRNA
EMBLY12883; CAA73383.1; -; mRNA
EMBLAF093852; AAC63376.1; -; mRNA
EMBLAF093853; AAC67553.1; -; Genomic_DNA
EMBLAF093857; AAD03716.1; -; Genomic_DNA
EMBLAF093854; AAD03716.1; JOINED; Genomic_DNA
EMBLAF093855; AAD03716.1; JOINED; Genomic_DNA
EMBLAF093856; AAD03716.1; JOINED; Genomic_DNA
EMBLAK030413; BAC26952.1; -; mRNA
EMBLBC013489; AAH13489.1; -; mRNA
IPIIPI00555059; -; .
RefSeqNP_031479.1; NM_007453.3; .
UniGeneMm.186185; -; .
ProteinModelPortalO08709; -; .
SMRO08709; 5-224; .
IntActO08709; 4; .
STRINGO08709; -; .
PhosphoSiteO08709; -; .
SWISS-2DPAGEO08709; -; .
COMPLUYEAST-2DPAGEO08709; -; .
REPRODUCTION-2DPAGEO08709; -; .
UCD-2DPAGEO08709; -; .
PRIDEO08709; -; .
GeneID11758; -; .
KEGGmmu:11758; -; .
CTD9588; -; .
MGIMGI:894320; Prdx6; .
eggNOGroNOG13330; -; .
HOVERGENHBG105234; -; .
InParanoidO08709; -; .
OrthoDBEOG4M399H; -; .
PhylomeDBO08709; -; .
BRENDA1.11.1.15; 3474; .
NextBio279511; -; .
ArrayExpressO08709; -; .
BgeeO08709; -; .
CleanExMM_PRDX5; -; .
CleanExMM_PRDX6; -; .
GenevestigatorO08709; -; .
GermOnlineENSMUSG00000026701; Mus musculus; .
GOGO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell; .
GOGO:0005829; C:cytosol; IDA:MGI; .
GOGO:0005764; C:lysosome; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0016787; F:hydrolase activity; IEA:UniProtKB-KW; .
GOGO:0004601; F:peroxidase activity; IMP:MGI; .
GOGO:0051920; F:peroxiredoxin activity; IEA:EC; .
GOGO:0032060; P:bleb assembly; IMP:MGI; .
GOGO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW; .
GOGO:0000302; P:response to reactive oxygen species; IMP:MGI; .
InterProIPR000866; AhpC/TSA; .
InterProIPR024706; Peroxiredoxin_AhpC-typ; .
InterProIPR019479; Peroxiredoxin_C; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PfamPF10417; 1-cysPrx_C; 1; .
PfamPF00578; AhpC-TSA; 1; .
PIRSFPIRSF000239; AHPC; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS51352; THIOREDOXIN_2; 1; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server