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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: O08749




SWISS-2DPAGE:  O08749


O08749


General information about the entry
View entry in simple text format
Entry nameDLDH_MOUSE
Primary accession numberO08749
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial; EC=1.8.1.4; AltName: Full=Dihydrolipoamide dehydrogenase; Flags: Precursor;.
Gene nameName=Dld
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ISLETS_MOUSE {Pancreatic islet cells}
Mus musculus (Mouse)
Tissue: Pancreatic islet
ISLETS_MOUSE
  map experimental info
  protein estimated location
 
ISLETS_MOUSE

MAP LOCATIONS:
pI=6.59; Mw=58739  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEO08749; O08749.
UniProtKB/Swiss-ProtO08749; DLDH_MOUSE.
World-2DPAGE RepositoryO08749; DLDH_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDLDH_MOUSE
Primary accession numberO08749
Secondary accession number(s) Q3TG55 Q3U5W5 Q3UWP7 Q99LD3
Sequence was last modified on November 28, 2006 (version 2)
Annotations were last modified on September 21, 2011 (version 107)
Name and origin of the protein
DescriptionRecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial; EC=1.8.1.4; AltName: Full=Dihydrolipoamide dehydrogenase; Flags: Precursor;
Gene nameName=Dld
Encoded onName=Dld
KeywordsAcetylation; Complete proteome; Direct protein sequencing; Disulfide bond; FAD; Flavoprotein; Mitochondrion; NAD; Oxidoreductase; Phosphoprotein; Redox-active center; Reference proteome; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU73445; AAC53170.1; -; mRNA
EMBLAK117104; BAE43405.1; -; mRNA
EMBLAK136193; BAE22867.1; -; mRNA
EMBLAK153399; BAE31961.1; -; mRNA
EMBLAK168875; BAE40693.1; -; mRNA
EMBLBC003368; AAH03368.1; -; mRNA
IPIIPI00874456; -; .
RefSeqNP_031887.2; NM_007861.4; .
UniGeneMm.3131; -; .
UniGeneMm.471230; -; .
ProteinModelPortalO08749; -; .
SMRO08749; 38-509; .
IntActO08749; 3; .
STRINGO08749; -; .
PhosphoSiteO08749; -; .
SWISS-2DPAGEO08749; -; .
REPRODUCTION-2DPAGEO08749; -; .
PRIDEO08749; -; .
EnsemblENSMUST00000110857; ENSMUSP00000106481; ENSMUSG00000020664; .
GeneID13382; -; .
KEGGmmu:13382; -; .
NMPDRfig|10090.3.peg.26069; -; .
UCSCuc007nhg.2; mouse; .
CTD1738; -; .
MGIMGI:107450; Dld; .
eggNOGroNOG12361; -; .
GeneTreeENSGT00550000074844; -; .
HOVERGENHBG002290; -; .
PhylomeDBO08749; -; .
NextBio283728; -; .
ArrayExpressO08749; -; .
BgeeO08749; -; .
CleanExMM_DLD; -; .
GenevestigatorO08749; -; .
GermOnlineENSMUSG00000020664; Mus musculus; .
GOGO:0043159; C:acrosomal matrix; IDA:MGI; .
GOGO:0019861; C:flagellum; IDA:MGI; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0004148; F:dihydrolipoyl dehydrogenase activity; IMP:MGI; .
GOGO:0045454; P:cell redox homeostasis; IEA:InterPro; .
GOGO:0007369; P:gastrulation; IMP:MGI; .
GOGO:0006120; P:mitochondrial electron transport; NADH to ubiquinone; IMP:MGI
GOGO:0006508; P:proteolysis; IDA:MGI; .
GOGO:0042391; P:regulation of membrane potential; IMP:MGI; .
GOGO:0048240; P:sperm capacitation; IDA:MGI; .
InterProIPR016156; FAD/NAD-linked_Rdtase_dimer; .
InterProIPR013027; FAD_pyr_nucl-diS_OxRdtase; .
InterProIPR006258; Lipoamide_DH; .
InterProIPR004099; Pyr_nucl-diS_OxRdtase_dimer; .
InterProIPR023753; Pyr_nucl-diS_OxRdtase_FAD/NAD; .
InterProIPR012999; Pyr_OxRdtase_I_AS; .
InterProIPR001327; Pyr_OxRdtase_NAD-bd_dom; .
Gene3DG3DSA:3.30.390.30; Pyr_redox_dim; 1; .
PANTHERPTHR22912:SF20; Lipoamide_DH; 1; .
PfamPF00070; Pyr_redox; 1; .
PfamPF07992; Pyr_redox_2; 1; .
PfamPF02852; Pyr_redox_dim; 1; .
PRINTSPR00368; FADPNR; .
SUPFAMSSF55424; FAD/NAD-linked_reductase_dimer; 1; .
TIGRFAMsTIGR01350; Lipoamide_DH; 1; .
PROSITEPS00076; PYRIDINE_REDOX_1; 1; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server