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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P01942




SWISS-2DPAGE:  P01942


P01942


General information about the entry
View entry in simple text format
Entry nameHBA_MOUSE
Primary accession numberP01942
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onMay 15, 2003 (version 3)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Full=Hemoglobin alpha chain;.
Gene nameName=Hba
Synonyms=Hba-a1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=8.73; Mw=12205
pI=8.39; Mw=12111
pI=8.13; Mw=12149

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=8.16; Mw=12126  [identification data]

MAPPING (identification):
MICROSEQUENCING [1], AND MASS FINGERPRINTING [1].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=7.83; Mw=12050  [identification data]

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL, AND MASS FINGERPRINTING [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=8.08; Mw=9945  [identification data]
pI=7.02; Mw=9516  [identification data]

MAPPING (identification):
SPOT 2D-001CKJ: MATCHING WITH THE MOUSE LIVER MASTER GEL [1];
SPOT 2D-001CLY: Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEP01942; P01942.
REPRODUCTION-2DPAGEIPI00469114; IPI00469114.
UniProtKB/Swiss-ProtP01942; HBA_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameHBA_MOUSE
Primary accession numberP01942
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Full=Hemoglobin alpha chain;
Gene nameName=Hba
Synonyms=Hba-a1
Encoded onName=Hba; Synonyms=Hba-a1
Keywords3D-structure; Complete proteome; Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport; Polymorphism; Reference proteome; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLV00714; CAA24095.1; -; Genomic_DNA
EMBLM10703; AAA37782.2; -; Genomic_DNA
EMBLM10840; AAA37784.1; -; mRNA
IPIIPI00469114; -; .
PIRA90791; HAMS; .
UniGeneMm.196110; -; .
UniGeneMm.471571; -; .
PDB3HRW; X-ray; 2.80 A; A/C=2-142
PDBsum3HRW; -; .
ProteinModelPortalP01942; -; .
SMRP01942; 2-142; .
IntActP01942; 6; .
STRINGP01942; -; .
PhosphoSiteP01942; -; .
SWISS-2DPAGEP01942; -; .
REPRODUCTION-2DPAGEIPI00469114; -; .
REPRODUCTION-2DPAGEP01942; -; .
PRIDEP01942; -; .
MGIMGI:96015; Hba-a1; .
eggNOGroNOG16000; -; .
HOGENOMHBG715197; -; .
HOVERGENHBG009709; -; .
InParanoidP01942; -; .
OrthoDBEOG47M209; -; .
BgeeP01942; -; .
CleanExMM_HBA-A1; -; .
GenevestigatorP01942; -; .
GermOnlineENSMUSG00000069917; Mus musculus; .
GermOnlineENSMUSG00000069919; Mus musculus; .
GOGO:0005833; C:hemoglobin complex; IEA:InterPro; .
GOGO:0020037; F:heme binding; IEA:InterPro; .
GOGO:0019825; F:oxygen binding; IEA:InterPro; .
GOGO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW; .
GOGO:0035634; P:response to stilbenoid; IEP:UniProtKB; .
InterProIPR009050; Globin-like; .
InterProIPR012292; Globin_dom; .
InterProIPR000971; Globin_subset; .
InterProIPR002338; Haemoglobin_a; .
InterProIPR018331; Haemoglobin_alpha_chain; .
InterProIPR002339; Haemoglobin_pi; .
Gene3DG3DSA:1.10.490.10; Globin_related; 1; .
PANTHERPTHR11442:SF14; Pi_haem; 1; .
PfamPF00042; Globin; 1; .
PRINTSPR00612; ALPHAHAEM; .
PRINTSPR00815; PIHAEM; .
SUPFAMSSF46458; Globin_like; 1; .
PROSITEPS01033; GLOBIN; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server