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SWISS-2DPAGE

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It will be discontinued on 31-May-2024.


SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P04632




SWISS-2DPAGE:  P04632


P04632


General information about the entry
View entry in simple text format
Entry nameCPNS1_HUMAN
Primary accession numberP04632
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=Calpain small subunit 1; Short=CSS1; AltName: Full=Calcium-activated neutral proteinase small subunit; Short=CANP small subunit; AltName: Full=Calcium-dependent protease small subunit; Short=CDPS; AltName: Full=Calcium-dependent protease small subunit 1; AltName: Full=Calpain regulatory subunit;.
Gene nameName=CAPNS1
Synonyms=CAPN4, CAPNS
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
Comments
  • SUBUNIT: Heterodimer of a large (catalytic) and a small (regulatory) subunit
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.81; Mw=25592  [identification data]

MAPPING (identification):
MALDI tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP04632.
REPRODUCTION-2DPAGEIPI00025084; IPI00025084.
Siena-2DPAGEP04632; CPNS1_HUMAN.
UniProtKB/Swiss-ProtP04632; CPNS1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCPNS1_HUMAN
Primary accession numberP04632
Secondary accession number(s) A8K0P1 Q8WTX3 Q96EW0
Sequence was last modified on August 13, 1987 (version 1)
Annotations were last modified on September 21, 2011 (version 135)
Name and origin of the protein
DescriptionRecName: Full=Calpain small subunit 1; Short=CSS1; AltName: Full=Calcium-activated neutral proteinase small subunit; Short=CANP small subunit; AltName: Full=Calcium-dependent protease small subunit; Short=CDPS; AltName: Full=Calcium-dependent protease small subunit 1; AltName: Full=Calpain regulatory subunit;
Gene nameName=CAPNS1
Synonyms=CAPN4, CAPNS
Encoded onName=CAPNS1; Synonyms=CAPN4, CAPNS
Keywords3D-structure; Acetylation; Calcium; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Membrane; Polymorphism; Reference proteome; Repeat.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX04106; CAA27726.1; -; mRNA
EMBLM31511; AAA35646.1; -; Genomic_DNA
EMBLM31502; AAA35646.1; JOINED; Genomic_DNA
EMBLM31503; AAA35646.1; JOINED; Genomic_DNA
EMBLM31504; AAA35646.1; JOINED; Genomic_DNA
EMBLM31505; AAA35646.1; JOINED; Genomic_DNA
EMBLM31506; AAA35646.1; JOINED; Genomic_DNA
EMBLM31507; AAA35646.1; JOINED; Genomic_DNA
EMBLM31508; AAA35646.1; JOINED; Genomic_DNA
EMBLM31509; AAA35646.1; JOINED; Genomic_DNA
EMBLM31510; AAA35646.1; JOINED; Genomic_DNA
EMBLAK289606; BAF82295.1; -; mRNA
EMBLBT009775; AAP88777.1; -; mRNA
EMBLAY789642; AAV40829.1; -; Genomic_DNA
EMBLAD001527; AAB51183.1; -; Genomic_DNA
EMBLAC002984; AAB81546.1; -; Genomic_DNA
EMBLBC000592; AAH00592.1; -; mRNA
EMBLBC007779; AAH07779.1; -; mRNA
EMBLBC011903; AAH11903.1; -; mRNA
EMBLBC017308; AAH17308.1; -; mRNA
EMBLBC018931; AAH18931.1; -; mRNA
EMBLBC021933; AAH21933.1; -; mRNA
EMBLBC023643; AAH23643.1; -; mRNA
EMBLBC064998; AAH64998.1; -; mRNA
IPIIPI00025084; -; .
PIRA26107; CIHUL; .
RefSeqNP_001003962.1; NM_001003962.1; .
RefSeqNP_001740.1; NM_001749.2; .
UniGeneHs.515371; -; .
PDB1KFU; X-ray; 2.50 A; S=85-268
PDB1KFX; X-ray; 3.15 A; S=85-268
PDBsum1KFU; -; .
PDBsum1KFX; -; .
ProteinModelPortalP04632; -; .
SMRP04632; 85-268; .
IntActP04632; 16; .
MINTMINT-5000880; -; .
STRINGP04632; -; .
PhosphoSiteP04632; -; .
SWISS-2DPAGEP04632; -; .
Cornea-2DPAGEP04632; -; .
OGPP04632; -; .
REPRODUCTION-2DPAGEIPI00025084; -; .
PRIDEP04632; -; .
EnsemblENST00000246533; ENSP00000246533; ENSG00000126247; .
EnsemblENST00000457326; ENSP00000400882; ENSG00000126247; .
GeneID826; -; .
KEGGhsa:826; -; .
UCSCuc002odj.1; human; .
CTD826; -; .
GeneCardsGC19P033136; -; .
H-InvDBHIX0015056; -; .
HGNCHGNC:1481; CAPNS1; .
HPAHPA006872; -; .
MIM114170; gene; .
neXtProtNX_P04632; -; .
PharmGKBPA26067; -; .
eggNOGprNOG05540; -; .
GeneTreeENSGT00580000081418; -; .
HOGENOMHBG747897; -; .
HOVERGENHBG004492; -; .
InParanoidP04632; -; .
OMARRYSDEG; -; .
OrthoDBEOG4W6NWR; -; .
PhylomeDBP04632; -; .
NextBio3398; -; .
ArrayExpressP04632; -; .
BgeeP04632; -; .
CleanExHS_CAPNS1; -; .
GenevestigatorP04632; -; .
GermOnlineENSG00000126247; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0005509; F:calcium ion binding; IEA:InterPro; .
GOGO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; TAS:ProtInc; .
GOGO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 1; .
SMARTSM00054; EFh; 3; .
PROSITEPS00018; EF_HAND_1; 2; .
PROSITEPS50222; EF_HAND_2; 3; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server