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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P06169 SWISS-2DPAGE:  P06169 P06169 General information about the entry View entry in simple text format Entry name PDC1_YEAST Primary accession number P06169 integrated into SWISS-2DPAGE on  February 1, 1995 (release 1) 2D Annotations were last modified on December 30, 2004 (version 1) General Annotations were last modified on  May 19, 2011 (version 13) Name and origin of the protein Description RecName: Full=Pyruvate decarboxylase isozyme 1; EC=4.1.1.-; EC=4.1.1.1;. Gene name Name=PDC1 OrderedLocusNames=YLR044C ORFNames=L2104 Annotated species Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. References [1]   MAPPING ON GEL MEDLINE=96314060; PubMed=8740180; [NCBI, Expasy, EBI, Israel, Japan] Sanchez J.-C., Golaz O., Frutiger S., Schaller D., Appel R.D., Bairoch A., Hughes G.J., Hochstrasser D.F. ''''''The yeast SWISS-2DPAGE database'';'';'' Electrophoresis 17(1):556-565(1996) [2]   MAPPING ON GEL MEDLINE=89073918; PubMed=3332961; [NCBI, Expasy, EBI, Israel, Japan] Bataille N., Peypouquet M.-F., Boucherie H. ''''''Identification of polypeptides of the carbon metabolism machinery on the two-dimensional protein map of Saccharomyces cerevisiae. Location of 23 additional polypeptides'';'';'' Yeast 3(1):11-21(1987) Comments SUBUNIT: HOMOTETRAMER 2D PAGE maps for identified proteins How to interpret a protein YEAST {Saccharomyces cerevisiae} Saccharomyces cerevisiae (Baker's yeast)   map experimental info   protein estimated location   YEAST MAP LOCATIONS: SPOT 2D-000IYT: pI=5.90; Mw=58619 SPOT 2D-000IZ4: pI=5.77; Mw=58619 SPOT 2D-000IZA: pI=5.65; Mw=58784 MAPPING (identification): GEL MATCHING [1] AND IDENTIFIED ON 2D GELS BY BATAILLE ET AL [2]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references COMPLUYEAST-2DPAGE P06169; PDC1_YEAST. UniProtKB/Swiss-Prot P06169; PDC1_YEAST. YEPD 6600. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name PDC1_YEAST Primary accession number P06169 Secondary accession number(s) D6VY46 O00042 Q07991 Q12682 Q12686 Q12687 Sequence was last modified on  January 23, 2007 (version 7) Annotations were last modified on  October 19, 2011 (version 143) Name and origin of the protein Description RecName: Full=Pyruvate decarboxylase isozyme 1; EC=4.1.1.-; EC=4.1.1.1; Gene name Name=PDC1 OrderedLocusNames=YLR044C ORFNames=L2104 Encoded on Name=PDC1; OrderedLocusNames=YLR044C; ORFNames=L2104 Keywords 3D-structure; Acetylation; Allosteric enzyme; Branched-chain amino acid catabolism; Complete proteome; Cytoplasm; Decarboxylase; Direct protein sequencing; Lyase; Magnesium; Metal-binding; Nucleus; Phenylalanine catabolism; Phosphoprotein; Reference proteome; Thiamine pyrophosphate; Tryptophan catabolism. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X04675; CAA28380.1; -; Genomic_DNA EMBL X77316; CAA54522.1; -; Genomic_DNA EMBL X94607; CAA64291.1; -; Genomic_DNA EMBL Z73216; CAA97573.1; -; Genomic_DNA EMBL Z73217; CAA97575.1; -; Genomic_DNA EMBL X77312; CAA54518.1; -; Genomic_DNA EMBL X77315; CAA54521.1; -; Genomic_DNA EMBL BK006945; DAA09362.1; -; Genomic_DNA PIR S64871; DCBYP; . RefSeq NP_013145.1; NM_001181931.1; . PDB 1PVD; X-ray; 2.30 A; A/B=2-556 PDB 1PYD; X-ray; 2.40 A; A/B=1-556 PDB 1QPB; X-ray; 2.40 A; A/B=1-563 PDB 2VK1; X-ray; 1.71 A; A/B/C/D=1-563 PDB 2VK8; X-ray; 1.42 A; A/B/C/D=1-563 PDB 2W93; X-ray; 1.60 A; A/B/C/D=1-563 PDBsum 1PVD; -; . PDBsum 1PYD; -; . PDBsum 1QPB; -; . PDBsum 2VK1; -; . PDBsum 2VK8; -; . PDBsum 2W93; -; . ProteinModelPortal P06169; -; . SMR P06169; 2-563; . DIP DIP-6773N; -; . IntAct P06169; 74; . MINT MINT-667063; -; . STRING P06169; -; . SWISS-2DPAGE P06169; -; . COMPLUYEAST-2DPAGE P06169; -; . PeptideAtlas P06169; -; . EnsemblFungi YLR044C; YLR044C; YLR044C; . GeneID 850733; -; . KEGG sce:YLR044C; -; . NMPDR fig|4932.3.peg.4136; -; . SGD S000004034; PDC1; . eggNOG fuNOG05694; -; . GeneTree EFGT00050000001792; -; . HOGENOM HBG479104; -; . OMA VITEVLY; -; . OrthoDB EOG41NXVF; -; . PhylomeDB P06169; -; . BioCyc MetaCyc:MONOMER-11722; -; . BRENDA 4.1.1.1; 984; . NextBio 966831; -; . ArrayExpress P06169; -; . Genevestigator P06169; -; . GermOnline YLR044C; Saccharomyces cerevisiae; . GO GO:0005829; C:cytosol; IDA:SGD; . GO GO:0005634; C:nucleus; IDA:SGD; . GO GO:0000287; F:magnesium ion binding; IEA:InterPro; . GO GO:0004737; F:pyruvate decarboxylase activity; IDA:SGD; . GO GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro; . GO GO:0016740; F:transferase activity; IEA:InterPro; . GO GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW; . GO GO:0019655; P:glucose catabolic process to ethanol; IDA:SGD; . GO GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW; . GO GO:0006090; P:pyruvate metabolic process; IDA:SGD; . GO GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW; . InterPro IPR012110; Pyruvt_ip_decrb; . InterPro IPR012000; Thiamin_PyroP_enz_cen_dom; . InterPro IPR012001; Thiamin_PyroP_enz_TPP-bd_dom; . InterPro IPR000399; TPP-bd_CS; . InterPro IPR011766; TPP_enzyme-bd_C; . PANTHER PTHR18968:SF4; PTHR18968:SF4; 1; . Pfam PF02775; TPP_enzyme_C; 1; . Pfam PF00205; TPP_enzyme_M; 1; . Pfam PF02776; TPP_enzyme_N; 1; . PIRSF PIRSF036565; Pyruvt_ip_decrb; 1; . PROSITE PS00187; TPP_ENZYMES; 1; . SWISS-2DPAGE (search AC)