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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P18760




SWISS-2DPAGE:  P18760


P18760


General information about the entry
View entry in simple text format
Entry nameCOF1_MOUSE
Primary accession numberP18760
integrated into SWISS-2DPAGE on October 1, 2001 (release 14)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;.
Gene nameName=Cfl1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11503206; [NCBI, Expasy, EBI, Israel, Japan]
Lanne B., Potthast F., Hoglund A., Brockenhuus Von Lowenhielm H., Nystrom A.-C., Nilsson F., Dahllof B.
''''''Thiourea enhances mapping of the proteome from murine white adipose tissue'';'';''
Proteomics 1(1):819-828(2001)
[2]   MAPPING ON GEL
Tonella L., Hoogland C., Sanchez J.-C.
Submitted (OCT-2001) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=6.60; Mw=13775

MAPPING (identification):
GEL MATCHING [2] WITH WAT_MOUSE 2-DE MAP FROM LANNE ET AL. [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEP18760; P18760.
UniProtKB/Swiss-ProtP18760; COF1_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCOF1_MOUSE
Primary accession numberP18760
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 120)
Name and origin of the protein
DescriptionRecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;
Gene nameName=Cfl1
Encoded onName=Cfl1
KeywordsAcetylation; Actin-binding; Cell membrane; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Nucleus; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD00472; BAA00364.1; -; mRNA
EMBLBC046225; AAH46225.1; -; mRNA
EMBLBC058726; AAH58726.1; -; mRNA
IPIIPI00407543; -; .
PIRS12584; S12584; .
RefSeqNP_031713.1; NM_007687.5; .
UniGeneMm.329655; -; .
ProteinModelPortalP18760; -; .
SMRP18760; 1-166; .
IntActP18760; 3; .
STRINGP18760; -; .
PhosphoSiteP18760; -; .
SWISS-2DPAGEP18760; -; .
REPRODUCTION-2DPAGEP18760; -; .
PRIDEP18760; -; .
GeneID12631; -; .
KEGGmmu:12631; -; .
CTD1072; -; .
MGIMGI:101757; Cfl1; .
eggNOGroNOG07842; -; .
HOVERGENHBG000381; -; .
OrthoDBEOG4WSWBP; -; .
ReactomeREACT_92778; Axon guidance; .
NextBio281816; -; .
ArrayExpressP18760; -; .
BgeeP18760; -; .
CleanExMM_CFL1; -; .
GenevestigatorP18760; -; .
GermOnlineENSMUSG00000056201; Mus musculus; .
GOGO:0030864; C:cortical actin cytoskeleton; IDA:MGI; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell; .
GOGO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; .
GOGO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0007015; P:actin filament organization; IMP:MGI; .
GOGO:0000910; P:cytokinesis; IMP:MGI; .
GOGO:0030010; P:establishment of cell polarity; IMP:MGI; .
GOGO:0001755; P:neural crest cell migration; IMP:MGI; .
GOGO:0001842; P:neural fold formation; IMP:MGI; .
GOGO:0030836; P:positive regulation of actin filament depolymerization; IMP:MGI; .
GOGO:0006468; P:protein phosphorylation; IDA:MGI; .
GOGO:0043200; P:response to amino acid stimulus; IDA:MGI; .
InterProIPR002108; Actin-bd_cofilin/tropomyosin; .
InterProIPR017904; ADF/Cofilin/Destrin; .
PfamPF00241; Cofilin_ADF; 1; .
PRINTSPR00006; COFILIN; .
SMARTSM00102; ADF; 1; .
PROSITEPS51263; ADF_H; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server