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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P22087 SWISS-2DPAGE:  P22087 P22087 General information about the entry View entry in simple text format Entry name FBRL_HUMAN Primary accession number P22087 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on May 15, 2003 (version 2) General Annotations were last modified on  May 19, 2011 (version 6) Name and origin of the protein Description RecName: Full=rRNA 2'-O-methyltransferase fibrillarin; EC=2.1.1.-; AltName: Full=34 kDa nucleolar scleroderma antigen;. Gene name Name=FBL Synonyms=FIB1, FLRN Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001V94: Mw=37156   [identification data] BAND 1D-001V95: Mw=36076   [identification data] MAPPING (identification): Tandem mass spectrometry [1]; BAND 1D-001V95: PEPTIDE MASS FINGERPRINTING [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references UniProtKB/Swiss-Prot P22087; FBRL_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name FBRL_HUMAN Primary accession number P22087 Secondary accession number(s) B5BUE8 O75259 Q6IAT5 Q9UPI6 Sequence was last modified on  June 20, 2001 (version 2) Annotations were last modified on  October 19, 2011 (version 121) Name and origin of the protein Description RecName: Full=rRNA 2'-O-methyltransferase fibrillarin; EC=2.1.1.-; AltName: Full=34 kDa nucleolar scleroderma antigen; Gene name Name=FBL Synonyms=FIB1, FLRN Encoded on Name=FBL; Synonyms=FIB1, FLRN Keywords 3D-structure; Acetylation; Complete proteome; Methylation; Methyltransferase; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; RNA-binding; rRNA processing; Transferase. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M59849; AAA52453.1; -; mRNA EMBL X56597; CAA39935.1; -; mRNA EMBL BT006830; AAP35476.1; -; mRNA EMBL BT020144; AAV38946.1; -; mRNA EMBL CR457069; CAG33350.1; -; mRNA EMBL AB451384; BAG70198.1; -; mRNA EMBL AC006950; AAD15623.1; -; Genomic_DNA EMBL AC005393; AAC28913.1; -; Genomic_DNA EMBL CH471126; EAW56925.1; -; Genomic_DNA EMBL BC019260; AAH19260.1; -; mRNA IPI IPI00025039; -; . PIR A38712; A38712; . RefSeq NP_001427.2; NM_001436.3; . UniGene Hs.299002; -; . PDB 2IPX; X-ray; 1.82 A; A=83-315 PDBsum 2IPX; -; . ProteinModelPortal P22087; -; . SMR P22087; 87-315; . DIP DIP-27569N; -; . IntAct P22087; 12; . MINT MINT-207612; -; . STRING P22087; -; . PhosphoSite P22087; -; . SWISS-2DPAGE P22087; -; . PeptideAtlas P22087; -; . PRIDE P22087; -; . Ensembl ENST00000221801; ENSP00000221801; ENSG00000105202; . GeneID 2091; -; . KEGG hsa:2091; -; . UCSC uc002omn.1; human; . CTD 2091; -; . GeneCards GC19M036772; -; . H-InvDB HIX0015126; -; . HGNC HGNC:3599; FBL; . HPA CAB001514; -; . MIM 134795; gene; . neXtProt NX_P22087; -; . PharmGKB PA28012; -; . eggNOG prNOG08878; -; . HOGENOM HBG297404; -; . HOVERGEN HBG002472; -; . InParanoid P22087; -; . OMA YERDHCI; -; . OrthoDB EOG4K3KX0; -; . PhylomeDB P22087; -; . NextBio 8479; -; . ArrayExpress P22087; -; . Bgee P22087; -; . CleanEx HS_FBL; -; . Genevestigator P22087; -; . GermOnline ENSG00000105202; Homo sapiens; . GO GO:0031428; C:box C/D snoRNP complex; NAS:BHF-UCL; . GO GO:0015030; C:Cajal body; IDA:BHF-UCL; . GO GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; TAS:ProtInc; . GO GO:0006364; P:rRNA processing; TAS:ProtInc; . GO GO:0008033; P:tRNA processing; IEA:InterPro; . InterPro IPR000692; Fibrillarin; . InterPro IPR020813; Fibrillarin_CS; . PANTHER PTHR10335; Fibrillarin; 1; . Pfam PF01269; Fibrillarin; 1; . PIRSF PIRSF006540; Nop17p; 1; . PRINTS PR00052; FIBRILLARIN; . PROSITE PS00566; FIBRILLARIN; 1; . SWISS-2DPAGE (search AC)