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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P31949 SWISS-2DPAGE:  P31949 P31949 General information about the entry View entry in simple text format Entry name S10AB_HUMAN Primary accession number P31949 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on May 15, 2003 (version 2) General Annotations were last modified on  May 19, 2011 (version 7) Name and origin of the protein Description RecName: Full=Protein S100-A11; AltName: Full=Calgizzarin; AltName: Full=Metastatic lymph node gene 70 protein; Short=MLN 70; AltName: Full=Protein S100-C; AltName: Full=S100 calcium-binding protein A11;. Gene name Name=S100A11 Synonyms=MLN70, S100C Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) Comments SUBUNIT: HOMODIMER; DISULFIDE-LINKED (BY SIMILARITY) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001V87: Mw=73806   [identification data] MAPPING (identification): Tandem mass spectrometry [1]. NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_2D_HUMAN MAP LOCATIONS: SPOT 2D-001W96: pI=6.26; Mw=13402   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P31949; P31949. DOSAC-COBS-2DPAGE P31949; S10AB_HUMAN. PMMA-2DPAGE P31949. UniProtKB/Swiss-Prot P31949; S10AB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name S10AB_HUMAN Primary accession number P31949 Secondary accession number(s) Q5VTK0 Sequence was last modified on  October 1, 1996 (version 2) Annotations were last modified on  September 21, 2011 (version 126) Name and origin of the protein Description RecName: Full=Protein S100-A11; AltName: Full=Calgizzarin; AltName: Full=Metastatic lymph node gene 70 protein; Short=MLN 70; AltName: Full=Protein S100-C; AltName: Full=S100 calcium-binding protein A11; Gene name Name=S100A11 Synonyms=MLN70, S100C Encoded on Name=S100A11; Synonyms=MLN70, S100C Keywords 3D-structure; Acetylation; Calcium; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Nucleus; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D38583; BAA07597.1; -; mRNA EMBL X80201; CAA56492.1; -; mRNA EMBL D49355; BAA08354.1; -; mRNA EMBL D50374; BAA23325.1; -; mRNA EMBL BT009912; AAP88914.1; -; mRNA EMBL AL591893; CAH72895.1; -; Genomic_DNA EMBL BC001410; AAH01410.1; -; mRNA EMBL BC014354; AAH14354.1; -; mRNA IPI IPI00013895; -; . PIR I37080; I37080; . RefSeq NP_005611.1; NM_005620.1; . UniGene Hs.417004; -; . PDB 1V4Z; NMR; -; A=1-19 PDB 1V50; NMR; -; A=1-19 PDBsum 1V4Z; -; . PDBsum 1V50; -; . ProteinModelPortal P31949; -; . SMR P31949; 5-104; . IntAct P31949; 6; . STRING P31949; -; . PhosphoSite P31949; -; . SWISS-2DPAGE P31949; -; . Aarhus/Ghent-2DPAGE 4006; IEF; . DOSAC-COBS-2DPAGE P31949; -; . PMMA-2DPAGE P31949; -; . PeptideAtlas P31949; -; . PRIDE P31949; -; . Ensembl ENST00000271638; ENSP00000271638; ENSG00000163191; . GeneID 6282; -; . KEGG hsa:6282; -; . UCSC uc001ezn.1; human; . CTD 6282; -; . GeneCards GC01M123382; -; . H-InvDB HIX0001073; -; . HGNC HGNC:10488; S100A11; . MIM 603114; gene; . neXtProt NX_P31949; -; . PharmGKB PA34900; -; . eggNOG prNOG20799; -; . GeneTree ENSGT00600000084283; -; . HOGENOM HBG716817; -; . HOVERGEN HBG001479; -; . InParanoid P31949; -; . OMA MSSPTET; -; . OrthoDB EOG4BG8XN; -; . PhylomeDB P31949; -; . NextBio 24385; -; . ArrayExpress P31949; -; . Bgee P31949; -; . CleanEx HS_S100A11; -; . Genevestigator P31949; -; . GermOnline ENSG00000163191; Homo sapiens; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0001726; C:ruffle; IDA:UniProtKB; . GO GO:0005509; F:calcium ion binding; IEA:InterPro; . GO GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0048154; F:S100 beta binding; IPI:UniProtKB; . GO GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc; . GO GO:0008156; P:negative regulation of DNA replication; TAS:ProtInc; . GO GO:0007165; P:signal transduction; TAS:UniProtKB; . InterPro IPR018248; EF-hand; . InterPro IPR011992; EF-hand-like_dom; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR018249; EF_HAND_2; . InterPro IPR001751; S100/CaBP-9k_CS; . InterPro IPR013787; S100_Ca-bd_sub; . Gene3D G3DSA:1.10.238.10; EF-Hand_type; 1; . Pfam PF00036; efhand; 1; . Pfam PF01023; S_100; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 1; . PROSITE PS00303; S100_CABP; 1; . SWISS-2DPAGE (search AC)