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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P35700




SWISS-2DPAGE:  P35700


P35700


General information about the entry
View entry in simple text format
Entry namePRDX1_MOUSE
Primary accession numberP35700
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-1; EC=1.11.1.15; AltName: Full=Macrophage 23 kDa stress protein; AltName: Full=Osteoblast-specific factor 3; Short=OSF-3; AltName: Full=Thioredoxin peroxidase 2; AltName: Full=Thioredoxin-dependent peroxide reductase 2;.
Gene nameName=Prdx1
Synonyms=Msp23, Paga, Tdpx2
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=6.59; Mw=20771

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=6.55; Mw=22827  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEP35700; P35700.
UniProtKB/Swiss-ProtP35700; PRDX1_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRDX1_MOUSE
Primary accession numberP35700
Secondary accession number(s) Q3UBV4 Q9CWI2
Sequence was last modified on June 1, 1994 (version 1)
Annotations were last modified on October 19, 2011 (version 126)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-1; EC=1.11.1.15; AltName: Full=Macrophage 23 kDa stress protein; AltName: Full=Osteoblast-specific factor 3; Short=OSF-3; AltName: Full=Thioredoxin peroxidase 2; AltName: Full=Thioredoxin-dependent peroxide reductase 2;
Gene nameName=Prdx1
Synonyms=Msp23, Paga, Tdpx2
Encoded onName=Prdx1; Synonyms=Msp23, Paga, Tdpx2
KeywordsAcetylation; Antioxidant; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Oxidoreductase; Peroxidase; Phosphoprotein; Redox-active center; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD16142; BAA03713.1; -; mRNA
EMBLD21252; BAA04796.1; -; mRNA
EMBLAF157331; AAD45323.1; -; Genomic_DNA
EMBLAF157329; AAD45323.1; JOINED; Genomic_DNA
EMBLAF157330; AAD45323.1; JOINED; Genomic_DNA
EMBLAB023564; BAA86992.1; -; Genomic_DNA
EMBLAK002287; BAB21990.1; -; mRNA
EMBLAK008711; BAB25847.1; -; mRNA
EMBLAK010688; BAB27120.1; -; mRNA
EMBLAK083243; BAC38827.1; -; mRNA
EMBLAK145138; BAE26255.1; -; mRNA
EMBLAK150797; BAE29860.1; -; mRNA
EMBLAK151459; BAE30417.1; -; mRNA
EMBLAK167624; BAE39676.1; -; mRNA
EMBLAK169154; BAE40933.1; -; mRNA
EMBLBC083348; AAH83348.1; -; mRNA
EMBLBC086648; AAH86648.1; -; mRNA
IPIIPI00121788; -; .
PIRA48513; A48513; .
RefSeqNP_035164.1; NM_011034.4; .
UniGeneMm.30929; -; .
ProteinModelPortalP35700; -; .
SMRP35700; 3-199; .
IntActP35700; 8; .
MINTMINT-1863043; -; .
STRINGP35700; -; .
PeroxiBase4555; Mm2CysPrx01-1; .
PhosphoSiteP35700; -; .
SWISS-2DPAGEP35700; -; .
REPRODUCTION-2DPAGEP35700; -; .
PRIDEP35700; -; .
EnsemblENSMUST00000106470; ENSMUSP00000102078; ENSMUSG00000028691; .
EnsemblENSMUST00000135573; ENSMUSP00000114159; ENSMUSG00000028691; .
GeneID18477; -; .
KEGGmmu:18477; -; .
NMPDRfig|10090.3.peg.10171; -; .
CTD5052; -; .
MGIMGI:99523; Prdx1; .
eggNOGroNOG06012; -; .
GeneTreeENSGT00390000004653; -; .
HOGENOMHBG493509; -; .
HOVERGENHBG000286; -; .
InParanoidP35700; -; .
OMASERADEF; -; .
PhylomeDBP35700; -; .
NextBio294178; -; .
ArrayExpressP35700; -; .
BgeeP35700; -; .
CleanExMM_PRDX1; -; .
GenevestigatorP35700; -; .
GermOnlineENSMUSG00000028691; Mus musculus; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0004601; F:peroxidase activity; IEA:UniProtKB-KW; .
GOGO:0051920; F:peroxiredoxin activity; IEA:EC; .
GOGO:0008283; P:cell proliferation; IMP:MGI; .
GOGO:0034101; P:erythrocyte homeostasis; IMP:MGI; .
GOGO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI; .
GOGO:0042345; P:regulation of NF-kappaB import into nucleus; IMP:MGI; .
GOGO:0032872; P:regulation of stress-activated MAPK cascade; IMP:MGI; .
GOGO:0019430; P:removal of superoxide radicals; IMP:MGI; .
InterProIPR000866; AhpC/TSA; .
InterProIPR024706; Peroxiredoxin_AhpC-typ; .
InterProIPR019479; Peroxiredoxin_C; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PfamPF10417; 1-cysPrx_C; 1; .
PfamPF00578; AhpC-TSA; 1; .
PIRSFPIRSF000239; AHPC; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS51352; THIOREDOXIN_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server