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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: ACON_HUMAN




SWISS-2DPAGE:  ACON_HUMAN


ACON_HUMAN


General information about the entry
View entry in simple text format
Entry nameACON_HUMAN
Primary accession numberQ99798
integrated into SWISS-2DPAGE on January 15, 1999 (release 9)
2D Annotations were last modified onDecember 1, 2000 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Aconitate hydratase, mitochondrial; Short=Aconitase; EC=4.2.1.3; AltName: Full=Citrate hydro-lyase; Flags: Precursor;.
Gene nameName=ACO2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=6.74; Mw=97476  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
DOSAC-COBS 2D-PAGEQ99798; Q99798.
DOSAC-COBS-2DPAGEQ99798; ACON_HUMAN.
REPRODUCTION-2DPAGEQ99798; Q99798.
REPRODUCTION-2DPAGEIPI00017855; IPI00017855.
UCD-2DPAGEQ99798; ACON_HUMAN.
UniProtKB/Swiss-ProtQ99798; ACON_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameACON_HUMAN
Primary accession numberQ99798
Secondary accession number(s) O75809 Q5JZ41 Q6FHX0 Q8TAQ6
Sequence was last modified on May 30, 2000 (version 2)
Annotations were last modified on October 19, 2011 (version 123)
Name and origin of the protein
DescriptionRecName: Full=Aconitate hydratase, mitochondrial; Short=Aconitase; EC=4.2.1.3; AltName: Full=Citrate hydro-lyase; Flags: Precursor;
Gene nameName=ACO2
Encoded onName=ACO2
Keywords4Fe-4S; Acetylation; Complete proteome; Direct protein sequencing; Iron; Iron-sulfur; Isopeptide bond; Lyase; Metal-binding; Mitochondrion; Polymorphism; Pyrrolidone carboxylic acid; Reference proteome; Transit peptide; Tricarboxylic acid cycle; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU80040; AAB38416.1; -; mRNA
EMBLU87939; AAC39921.1; -; Genomic_DNA
EMBLU87926; AAC39921.1; JOINED; Genomic_DNA
EMBLU87927; AAC39921.1; JOINED; Genomic_DNA
EMBLU87928; AAC39921.1; JOINED; Genomic_DNA
EMBLU87929; AAC39921.1; JOINED; Genomic_DNA
EMBLU87930; AAC39921.1; JOINED; Genomic_DNA
EMBLU87931; AAC39921.1; JOINED; Genomic_DNA
EMBLU87932; AAC39921.1; JOINED; Genomic_DNA
EMBLU87933; AAC39921.1; JOINED; Genomic_DNA
EMBLU87934; AAC39921.1; JOINED; Genomic_DNA
EMBLU87935; AAC39921.1; JOINED; Genomic_DNA
EMBLU87936; AAC39921.1; JOINED; Genomic_DNA
EMBLU87937; AAC39921.1; JOINED; Genomic_DNA
EMBLU87938; AAC39921.1; JOINED; Genomic_DNA
EMBLCR456365; CAG30251.1; -; mRNA
EMBLCR536568; CAG38805.1; -; mRNA
EMBLAL023553; CAI20278.1; -; Genomic_DNA
EMBLAL008582; CAI20278.1; JOINED; Genomic_DNA
EMBLAL008582; CAI17931.1; -; Genomic_DNA
EMBLAL023553; CAI17931.1; JOINED; Genomic_DNA
EMBLBC014092; AAH14092.1; -; mRNA
EMBLBC026196; AAH26196.1; -; mRNA
IPIIPI00017855; -; .
PIRS17526; S17526; .
PIRT52543; T52543; .
RefSeqNP_001089.1; NM_001098.2; .
UniGeneHs.643610; -; .
UniGeneHs.712617; -; .
ProteinModelPortalQ99798; -; .
SMRQ99798; 29-780; .
IntActQ99798; 1; .
MINTMINT-2856402; -; .
STRINGQ99798; -; .
PhosphoSiteQ99798; -; .
SWISS-2DPAGEQ99798; -; .
DOSAC-COBS-2DPAGEQ99798; -; .
REPRODUCTION-2DPAGEIPI00017855; -; .
REPRODUCTION-2DPAGEQ99798; -; .
UCD-2DPAGEQ99798; -; .
PRIDEQ99798; -; .
EnsemblENST00000216254; ENSP00000216254; ENSG00000100412; .
GeneID50; -; .
KEGGhsa:50; -; .
NMPDRfig|9606.3.peg.21789; -; .
UCSCuc003bac.1; human; .
CTD50; -; .
GeneCardsGC22P024830; -; .
H-InvDBHIX0016520; -; .
HGNCHGNC:118; ACO2; .
HPAHPA001097; -; .
MIM100850; gene; .
neXtProtNX_Q99798; -; .
PharmGKBPA24443; -; .
eggNOGprNOG17068; -; .
GeneTreeENSGT00530000063060; -; .
HOVERGENHBG000248; -; .
OrthoDBEOG4BCDM9; -; .
PhylomeDBQ99798; -; .
BioCycMetaCyc:ENSG00000100412-MONOMER; -; .
ReactomeREACT_1046; Pyruvate metabolism and Citric Acid (TCA) cycle; .
NextBio195; -; .
ArrayExpressQ99798; -; .
BgeeQ99798; -; .
CleanExHS_ACO2; -; .
GenevestigatorQ99798; -; .
GermOnlineENSG00000100412; Homo sapiens; .
GOGO:0005759; C:mitochondrial matrix; TAS:Reactome; .
GOGO:0005634; C:nucleus; IDA:HPA; .
GOGO:0051539; F:4 iron; 4 sulfur cluster binding; IEA:UniProtKB-KW
GOGO:0003994; F:aconitate hydratase activity; IEA:EC; .
GOGO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GOGO:0005506; F:iron ion binding; IDA:MGI; .
GOGO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GOGO:0006101; P:citrate metabolic process; IDA:MGI; .
GOGO:0006099; P:tricarboxylic acid cycle; IDA:MGI; .
InterProIPR015931; Acnase/IPM_dHydase_lsu_aba_1/3; .
InterProIPR015937; Acoase/IPM_deHydtase; .
InterProIPR001030; Acoase/IPM_deHydtase_lsu_aba; .
InterProIPR015928; Aconitase/3IPM_dehydase_swvl; .
InterProIPR015932; Aconitase/IPMdHydase_lsu_aba_2; .
InterProIPR018136; Aconitase_4Fe-4S_BS; .
InterProIPR006248; Aconitase_mito-like; .
InterProIPR000573; AconitaseA/IPMdHydase_ssu_swvl; .
Gene3DG3DSA:3.30.499.10; Acnase/IPM_dHydase_lsu_aba_1/3; 2; .
Gene3DG3DSA:3.20.19.10; Aconitase/3IPM_dehydase_swvl; 1; .
Gene3DG3DSA:3.40.1060.10; Aconitase/IPMdHydase_lsu_aba_2; 1; .
PANTHERPTHR11670; Aconitase-like_core; 1; .
PANTHERPTHR11670:SF5; Aconitase_mito; 1; .
PfamPF00330; Aconitase; 1; .
PfamPF00694; Aconitase_C; 1; .
PRINTSPR00415; ACONITASE; .
SUPFAMSSF52016; Aconitase/3IPM_dehydase_swvl; 1; .
SUPFAMSSF53732; Aconitase_N; 1; .
TIGRFAMsTIGR01340; Aconitase_mito; 1; .
PROSITEPS00450; ACONITASE_1; 1; .
PROSITEPS01244; ACONITASE_2; 1; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server