World-2DPAGE Home


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: DOPD_HUMAN




SWISS-2DPAGE:  DOPD_HUMAN


DOPD_HUMAN


General information about the entry
View entry in simple text format
Entry nameDOPD_HUMAN
Primary accession numberP30046
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 30, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=D-dopachrome decarboxylase; EC=4.1.1.84; AltName: Full=D-dopachrome tautomerase; AltName: Full=Phenylpyruvate tautomerase II;.
Gene nameName=DDT
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, ExPASy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
[3]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=6.47; Mw=12009

MAPPING (identification):
MICROSEQUENCING [1].



LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=7.94; Mw=16072  [identification data]

MAPPING (identification):
MALDI tandem mass spectrometry [3].



LYMPHOMA_HUMAN {Lymphoma}
Homo sapiens (Human)
Tissue: Lymphoma
LYMPHOMA_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOMA_HUMAN

MAP LOCATIONS:
pI=6.35; Mw=10459

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
UCD-2DPAGEP30046; DOPD_HUMAN.
UniProtKB/Swiss-ProtP30046; DOPD_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDOPD_HUMAN
Primary accession numberP30046
Secondary accession number(s) O00774 O60787 Q13534
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 118)
Name and origin of the protein
DescriptionRecName: Full=D-dopachrome decarboxylase; EC=4.1.1.84; AltName: Full=D-dopachrome tautomerase; AltName: Full=Phenylpyruvate tautomerase II;
Gene nameName=DDT
Encoded onName=DDT
Keywords3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Lyase; Melanin biosynthesis; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU49785; AAB48546.1; -; mRNA
EMBLU84143; AAB41503.1; -; mRNA
EMBLY11151; CAA72037.1; -; Genomic_DNA
EMBLAF012434; AAC77468.1; -; Genomic_DNA
EMBLAF012432; AAC77468.1; JOINED; Genomic_DNA
EMBLAF012433; AAC77468.1; JOINED; Genomic_DNA
EMBLAF058293; AAC13717.1; -; Genomic_DNA
EMBLCR456431; CAG30317.1; -; mRNA
EMBLZ84718; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC005971; AAH05971.1; -; mRNA
EMBLBC015508; AAH15508.1; -; mRNA
IPIIPI00293867; -; .
PIRG02438; G02438; .
PIRJE0162; JE0162; .
RefSeqNP_001077861.1; NM_001084392.1; .
RefSeqNP_001346.1; NM_001355.3; .
UniGeneHs.656723; -; .
PDB1DPT; X-ray; 1.54 A; A/B/C=2-118
PDB3KAN; X-ray; 1.13 A; A/B/C=2-118
PDBsum1DPT; -; .
PDBsum3KAN; -; .
ProteinModelPortalP30046; -; .
SMRP30046; 2-118; .
IntActP30046; 1; .
STRINGP30046; -; .
PhosphoSiteP30046; -; .
SWISS-2DPAGEP30046; -; .
UCD-2DPAGEP30046; -; .
PeptideAtlasP30046; -; .
PRIDEP30046; -; .
EnsemblENST00000350608; ENSP00000215773; ENSG00000099977; .
EnsemblENST00000398344; ENSP00000381386; ENSG00000099977; .
EnsemblENST00000404092; ENSP00000385714; ENSG00000099977; .
GeneID1652; -; .
KEGGhsa:1652; -; .
UCSCuc002zyz.2; human; .
CTD1652; -; .
GeneCardsGC22M007261; -; .
HGNCHGNC:2732; DDT; .
MIM602750; gene; .
neXtProtNX_P30046; -; .
PharmGKBPA27197; -; .
eggNOGprNOG20374; -; .
HOVERGENHBG003240; -; .
OrthoDBEOG46T330; -; .
PhylomeDBP30046; -; .
BRENDA4.1.1.84; 2681; .
NextBio6800; -; .
ArrayExpressP30046; -; .
BgeeP30046; -; .
CleanExHS_DDT; -; .
GenevestigatorP30046; -; .
GermOnlineENSG00000099977; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC; .
GOGO:0004167; F:dopachrome isomerase activity; TAS:ProtInc; .
GOGO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW; .
InterProIPR001398; Macrophage_inhib_fac; .
InterProIPR019829; Macrophage_inhib_fac_CS; .
InterProIPR014347; Tautomerase; .
Gene3DG3DSA:3.30.429.10; Tautomerase; 1; .
PANTHERPTHR11954; MIF; 1; .
PfamPF01187; MIF; 1; .
ProDomPD004816; Macrophage_inhib_fac; 1; .
SUPFAMSSF55331; SSF55331; 1; .
PROSITEPS01158; MIF; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server