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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: MYL6_HUMAN




SWISS-2DPAGE:  MYL6_HUMAN


MYL6_HUMAN


General information about the entry
View entry in simple text format
Entry nameMYL6_HUMAN
Primary accession numberP60660
Secondary accession number(s) P16475
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 10)
Name and origin of the protein
DescriptionRecName: Full=Myosin light polypeptide 6; AltName: Full=17 kDa myosin light chain; Short=LC17; AltName: Full=Myosin light chain 3; Short=MLC-3; AltName: Full=Myosin light chain alkali 3; Short=Myosin light chain A3; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6;.
Gene nameName=MYL6
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=20529951; PubMed=11079567; [NCBI, ExPASy, EBI, Israel, Japan]
Jung E., Hoogland C., Chiappe D., Sanchez J.-C., Hochstrasser D.F.
''''''The establishment of a human liver nuclei 2-DE reference map'';'';''
Electrophoresis 21(1):3483-3487(2000)
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.35; Mw=17424  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].



NUCLEI_LIVER_HUMAN {Soluble nuclear proteins and matrix from liver tissue}
Homo sapiens (Human)
Tissue: Liver
NUCLEI_LIVER_HUMAN
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_HUMAN

MAP LOCATIONS:
pI=4.38; Mw=13214  [identification data]
pI=4.46; Mw=12967  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
DOSAC-COBS 2D-PAGEP60660; P60660.
DOSAC-COBS-2DPAGEP60660; MYL6_HUMAN.
OGP-WWWP16475.
UniProtKB/Swiss-ProtP60660; MYL6_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameMYL6_HUMAN
Primary accession numberP60660
Secondary accession number(s) P16475 P24572 P24573 Q12790 Q561V9 Q6IAZ0 Q6IPY5
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 84)
Name and origin of the protein
DescriptionRecName: Full=Myosin light polypeptide 6; AltName: Full=17 kDa myosin light chain; Short=LC17; AltName: Full=Myosin light chain 3; Short=MLC-3; AltName: Full=Myosin light chain alkali 3; Short=Myosin light chain A3; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6;
Gene nameName=MYL6
Encoded onName=MYL6
KeywordsAcetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Motor protein; Muscle protein; Myosin; Phosphoprotein; Polymorphism; Reference proteome; Repeat.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM22918; AAA36347.1; -; mRNA
EMBLM22919; AAA59892.1; -; Genomic_DNA
EMBLM22919; AAA59893.1; -; Genomic_DNA
EMBLM22920; AAA36348.1; -; mRNA
EMBLM31212; AAA59853.1; -; mRNA
EMBLU02629; AAA20643.1; -; mRNA
EMBLAB046613; BAB62402.1; -; mRNA
EMBLCR457014; CAG33295.1; -; mRNA
EMBLBC006781; AAH06781.2; -; mRNA
EMBLBC017455; AAH17455.1; -; mRNA
EMBLBC071661; AAH71661.1; -; mRNA
EMBLBC093066; AAH93066.1; -; mRNA
IPIIPI00335168; -; .
IPIIPI00789605; -; .
PIRA33709; MOHU6N; .
PIRA49620; MOHU6E; .
PIRB33709; MOHU6M; .
RefSeqNP_066299.2; NM_021019.4; .
RefSeqNP_524147.2; NM_079423.3; .
UniGeneHs.632717; -; .
ProteinModelPortalP60660; -; .
SMRP60660; 4-151; .
IntActP60660; 17; .
MINTMINT-1131667; -; .
STRINGP60660; -; .
PhosphoSiteP60660; -; .
SWISS-2DPAGEP60660; -; .
DOSAC-COBS-2DPAGEP60660; -; .
PRIDEP60660; -; .
EnsemblENSRNOT00000049160; ENSRNOP00000040759; ENSRNOG00000003892; .
EnsemblENST00000348108; ENSP00000301540; ENSG00000092841; .
GeneID4637; -; .
KEGGhsa:4637; -; .
UCSCuc001sjw.1; human; .
CTD4637; -; .
GeneCardsGC12P053591; -; .
H-InvDBHIX0010720; -; .
HGNCHGNC:7587; MYL6; .
MIM609931; gene; .
neXtProtNX_P60660; -; .
PharmGKBPA31384; -; .
eggNOGprNOG14036; -; .
GeneTreeENSGT00590000082921; -; .
HOVERGENHBG012180; -; .
InParanoidP60660; -; .
OMAMNHKLLD; -; .
PhylomeDBP60660; -; .
ReactomeREACT_17044; Muscle contraction; .
ReactomeREACT_18266; Axon guidance; .
NextBio17854; -; .
ArrayExpressP60660; -; .
BgeeP60660; -; .
CleanExHS_MYL6; -; .
GenevestigatorP60660; -; .
GermOnlineENSG00000092841; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0016461; C:unconventional myosin complex; TAS:BHF-UCL; .
GOGO:0030898; F:actin-dependent ATPase activity; ISS:HGNC; .
GOGO:0005509; F:calcium ion binding; IEA:InterPro; .
GOGO:0003774; F:motor activity; TAS:HGNC; .
GOGO:0005515; F:protein binding; IPI:IntAct; .
GOGO:0008307; F:structural constituent of muscle; IDA:HGNC; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0030049; P:muscle filament sliding; TAS:HGNC; .
GOGO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 2; .
SMARTSM00054; EFh; 2; .
PROSITEPS50222; EF_HAND_2; 2; .



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