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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P10606




SWISS-2DPAGE:  P10606


P10606


General information about the entry
View entry in simple text format
Entry nameCOX5B_HUMAN
Primary accession numberP10606
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 1, 2000 (version 2)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome c oxidase subunit 5B, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide Vb; Flags: Precursor;.
Gene nameName=COX5B
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=94147969; PubMed=8313870; [NCBI, ExPASy, EBI, Israel, Japan]
Hughes G.J., Frutiger S., Paquet N., Pasquali C., Sanchez J.-C., Tissot J.-D., Bairoch A., Appel R.D., Hochstrasser D.F.
''''''Human liver protein map: update 1993'';'';''
Electrophoresis 14(1):1216-1222(1993)
[2]   MAPPING ON GEL
MEDLINE=98163346; PubMed=9504818; [NCBI, ExPASy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.
''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';''
Electrophoresis 18(1):2842-2848(1997)
Comments
  • SUBUNIT: ONE OF THE NUCLEAR-CODED POLYPEPTIDE CHAINS OF CYTOCHROME C OXIDASE
2D PAGE maps for identified proteins
How to interpret a protein

CEC_HUMAN {Colorectal epithelia cells}
Homo sapiens (Human)
Tissue: Colon epithelium
CEC_HUMAN
  map experimental info
  protein estimated location
 
CEC_HUMAN

MAP LOCATIONS:
pI=5.62; Mw=12121

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=5.58; Mw=12938

MAPPING (identification):
MICROSEQUENCING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
UniProtKB/Swiss-ProtP10606; COX5B_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCOX5B_HUMAN
Primary accession numberP10606
Secondary accession number(s) Q96J18 Q99610
Sequence was last modified on April 3, 2002 (version 2)
Annotations were last modified on September 21, 2011 (version 119)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome c oxidase subunit 5B, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide Vb; Flags: Precursor;
Gene nameName=COX5B
Encoded onName=COX5B
KeywordsAcetylation; Complete proteome; Direct protein sequencing; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM19961; AAA52061.1; -; mRNA
EMBLM59250; AAA52060.1; -; Genomic_DNA
EMBLBC006229; AAH06229.1; -; mRNA
EMBLU41284; AAB19185.1; -; Genomic_DNA
IPIIPI00021785; -; .
PIRJT0324; OTHU5B; .
RefSeqNP_001853.2; NM_001862.2; .
UniGeneHs.1342; -; .
ProteinModelPortalP10606; -; .
SMRP10606; 32-129; .
IntActP10606; 1; .
STRINGP10606; -; .
TCDB3.D.4.11.1; proton-translocating cytochrome oxidase (COX) superfamily; .
PhosphoSiteP10606; -; .
SWISS-2DPAGEP10606; -; .
PeptideAtlasP10606; -; .
PRIDEP10606; -; .
EnsemblENST00000258424; ENSP00000258424; ENSG00000135940; .
GeneID1329; -; .
KEGGhsa:1329; -; .
UCSCuc002sya.1; human; .
CTD1329; -; .
GeneCardsGC02P092031; -; .
H-InvDBHIX0002290; -; .
HGNCHGNC:2269; COX5B; .
HPAHPA034517; -; .
MIM123866; gene; .
neXtProtNX_P10606; -; .
PharmGKBPA26786; -; .
eggNOGprNOG20077; -; .
HOGENOMHBG748384; -; .
HOVERGENHBG051089; -; .
InParanoidP10606; -; .
OMACEEDQTY; -; .
OrthoDBEOG495ZT9; -; .
PhylomeDBP10606; -; .
ReactomeREACT_6305; Respiratory electron transport; ATP synthesis by chemiosmotic coupling; and heat production by uncoupling proteins
NextBio5413; -; .
ArrayExpressP10606; -; .
BgeeP10606; -; .
CleanExHS_COX5B; -; .
GenevestigatorP10606; -; .
GermOnlineENSG00000135940; Homo sapiens; .
GOGO:0005743; C:mitochondrial inner membrane; TAS:Reactome; .
GOGO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0022904; P:respiratory electron transport chain; TAS:Reactome; .
GOGO:0007585; P:respiratory gaseous exchange; TAS:ProtInc; .
InterProIPR002124; Cyt_c_oxidase_su5b; .
InterProIPR020893; Cyt_c_oxidase_su5b_Zn_BS; .
Gene3DG3DSA:2.60.11.10; COX5B; 1; .
PANTHERPTHR10122; COX5B; 1; .
PfamPF01215; COX5B; 1; .
ProDomPD007270; Cyt_c_oxidase_su5b; 1; .
PROSITEPS00848; COX5B_1; 1; .
PROSITEPS51359; COX5B_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server