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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P35268



General information about the entry
View entry in simple text format
Entry nameRL22_HUMAN
Primary accession numberP35268
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L22; AltName: Full=EBER-associated protein; Short=EAP; AltName: Full=Epstein-Barr virus small RNA-associated protein; AltName: Full=Heparin-binding protein HBp15;.
Gene nameName=RPL22
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=18078  [identification data]
Mw=17654  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP35268; RL22_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRL22_HUMAN
Primary accession numberP35268
Secondary accession number(s) B2R495 Q6IBD1
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 106)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L22; AltName: Full=EBER-associated protein; Short=EAP; AltName: Full=Epstein-Barr virus small RNA-associated protein; AltName: Full=Heparin-binding protein HBp15;
Gene nameName=RPL22
Encoded onName=RPL22
KeywordsComplete proteome; Direct protein sequencing; Heparin-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX59357; CAA42007.1; -; mRNA
EMBLD17652; BAA04545.1; -; mRNA
EMBLAK311749; BAG34692.1; -; mRNA
EMBLCR456873; CAG33154.1; -; mRNA
EMBLAL031847; CAI19448.1; -; Genomic_DNA
EMBLCH471130; EAW71518.1; -; Genomic_DNA
EMBLBC035566; AAH35566.1; -; mRNA
EMBLBC058887; AAH58887.1; -; mRNA
EMBLBC066314; AAH66314.1; -; mRNA
IPIIPI00219153; -; .
PIRJC2120; JC2120; .
RefSeqNP_000974.1; NM_000983.3; .
UniGeneHs.515329; -; .
UniGeneHs.554762; -; .
ProteinModelPortalP35268; -; .
SMRP35268; 12-117; .
IntActP35268; 12; .
MINTMINT-1149755; -; .
STRINGP35268; -; .
PhosphoSiteP35268; -; .
SWISS-2DPAGEP35268; -; .
PeptideAtlasP35268; -; .
PRIDEP35268; -; .
EnsemblENST00000234875; ENSP00000346088; ENSG00000116251; .
GeneID6146; -; .
KEGGhsa:6146; -; .
UCSCuc001amd.1; human; .
CTD6146; -; .
H-InvDBHIX0000074; -; .
HGNCHGNC:10315; RPL22; .
MIM180474; gene; .
neXtProtNX_P35268; -; .
PharmGKBPA34688; -; .
eggNOGprNOG21084; -; .
HOGENOMHBG716459; -; .
HOVERGENHBG004373; -; .
InParanoidP35268; -; .
OrthoDBEOG4BRWNB; -; .
PhylomeDBP35268; -; .
ReactomeREACT_13698; Regulation of beta-cell development; .
ReactomeREACT_15380; Diabetes pathways; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_1762; 3' -UTR-mediated translational regulation; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_6167; Influenza Infection; .
ReactomeREACT_71; Gene Expression; .
NextBio23879; -; .
ArrayExpressP35268; -; .
BgeeP35268; -; .
CleanExHS_RPL22; -; .
GenevestigatorP35268; -; .
GermOnlineENSG00000116251; Homo sapiens; .
GOGO:0022625; C:cytosolic large ribosomal subunit; TAS:ProtInc; .
GOGO:0008201; F:heparin binding; IEA:UniProtKB-KW; .
GOGO:0003723; F:RNA binding; TAS:ProtInc; .
GOGO:0003735; F:structural constituent of ribosome; TAS:ProtInc; .
GOGO:0031018; P:endocrine pancreas development; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0006414; P:translational elongation; TAS:Reactome; .
GOGO:0006415; P:translational termination; TAS:Reactome; .
GOGO:0019083; P:viral transcription; TAS:Reactome; .
InterProIPR002671; Ribosomal_L22e; .
PANTHERPTHR10064; Ribosomal_L22e; 1; .
PfamPF01776; Ribosomal_L22e; 1; .


SWISS-2DPAGE (search AC)

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