World-2DPAGE Home


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P56537




SWISS-2DPAGE:  P56537


P56537


General information about the entry
View entry in simple text format
Entry nameIF6_HUMAN
Primary accession numberP56537
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 6; Short=eIF-6; AltName: Full=B(2)GCN homolog; AltName: Full=B4 integrin interactor; AltName: Full=CAB; AltName: Full=p27(BBP);.
Gene nameName=EIF6
Synonyms=EIF3A, ITGB4BP
ORFNames=OK/SW-cl.27
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=29157  [identification data]

MAPPING (identification):
Peptide mass fingerprinting and tandem mass SPECTROMETRY [1].



NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=5.94; Mw=33604  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
OGP-WWWP56537.
REPRODUCTION-2DPAGEIPI00010105; IPI00010105.
UniProtKB/Swiss-ProtP56537; IF6_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameIF6_HUMAN
Primary accession numberP56537
Secondary accession number(s) Q6IBN8 Q96TD5
Sequence was last modified on July 15, 1998 (version 1)
Annotations were last modified on October 19, 2011 (version 112)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 6; Short=eIF-6; AltName: Full=B(2)GCN homolog; AltName: Full=B4 integrin interactor; AltName: Full=CAB; AltName: Full=p27(BBP);
Gene nameName=EIF6
Synonyms=EIF3A, ITGB4BP
ORFNames=OK/SW-cl.27
Encoded onName=EIF6; Synonyms=EIF3A, ITGB4BP; ORFNames=OK/SW-cl.27
KeywordsComplete proteome; Cytoplasm; Initiation factor; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Ribosome biogenesis.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF022229; AAB97735.1; -; mRNA
EMBLY11435; CAA72243.1; -; mRNA
EMBLAF289541; AAK39426.1; -; Genomic_DNA
EMBLAF289540; AAK39426.1; JOINED; Genomic_DNA
EMBLAF047433; AAC39897.1; -; mRNA
EMBLAK314969; BAG37470.1; -; mRNA
EMBLAB062289; BAB93472.1; -; mRNA
EMBLCR456764; CAG33045.1; -; mRNA
EMBLAL121753; CAX12724.1; -; Genomic_DNA
EMBLCH471077; EAW76221.1; -; Genomic_DNA
EMBLBC001119; AAH01119.1; -; mRNA
EMBLBC011845; AAH11845.1; -; mRNA
EMBLBC019305; AAH19305.1; -; mRNA
IPIIPI00010105; -; .
RefSeqNP_002203.1; NM_002212.2; .
RefSeqNP_852131.1; NM_181466.1; .
RefSeqNP_852133.1; NM_181468.1; .
UniGeneHs.654848; -; .
ProteinModelPortalP56537; -; .
SMRP56537; 1-224; .
IntActP56537; 3; .
STRINGP56537; -; .
PhosphoSiteP56537; -; .
SWISS-2DPAGEP56537; -; .
OGPP56537; -; .
REPRODUCTION-2DPAGEIPI00010105; -; .
PeptideAtlasP56537; -; .
PRIDEP56537; -; .
EnsemblENST00000374436; ENSP00000363559; ENSG00000242372; .
EnsemblENST00000374450; ENSP00000363574; ENSG00000242372; .
GeneID3692; -; .
KEGGhsa:3692; -; .
UCSCuc002xbv.1; human; .
CTD3692; -; .
GeneCardsGC20M030645; -; .
H-InvDBHIX0015761; -; .
HGNCHGNC:6159; EIF6; .
MIM602912; gene; .
neXtProtNX_P56537; -; .
PharmGKBPA29958; -; .
eggNOGprNOG11577; -; .
GeneTreeENSGT00390000015972; -; .
HOGENOMHBG589638; -; .
HOVERGENHBG001300; -; .
InParanoidP56537; -; .
OMAQFENSNE; -; .
OrthoDBEOG4STS5C; -; .
PhylomeDBP56537; -; .
NextBio14465; -; .
ArrayExpressP56537; -; .
BgeeP56537; -; .
CleanExHS_EIF3A; -; .
CleanExHS_EIF6; -; .
GenevestigatorP56537; -; .
GermOnlineENSG00000126005; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005730; C:nucleolus; IEA:UniProtKB-SubCell; .
GOGO:0043022; F:ribosome binding; IDA:UniProtKB; .
GOGO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW; .
GOGO:0042256; P:mature ribosome assembly; IMP:UniProtKB; .
InterProIPR002769; eIF6; .
PANTHERPTHR10784; eIF6; 1; .
PfamPF01912; eIF-6; 1; .
PIRSFPIRSF006413; IF-6; 1; .
SMARTSM00654; eIF6; 1; .
TIGRFAMsTIGR00323; EIF-6; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server