World-2DPAGE Home


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P62158




SWISS-2DPAGE:  P62158


P62158


General information about the entry
View entry in simple text format
Entry nameCALM_HUMAN
Primary accession numberP62158
Secondary accession number(s) P02593
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Calmodulin; Short=CaM;.
Gene nameName=CALM1
Synonyms=CALM, CAM, CAM1
   and
Name=CALM2
Synonyms=CAM2, CAMB
   and
Name=CALM3
Synonyms=CALML2, CAM3, CAMC, CAMIII
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.26; Mw=17661  [identification data]
pI=4.22; Mw=16594  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
DOSAC-COBS 2D-PAGEP62158; P62158.
DOSAC-COBS-2DPAGEP62158; CALM_HUMAN.
OGP-WWWP02593.
UniProtKB/Swiss-ProtP62158; CALM_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCALM_HUMAN
Primary accession numberP62158
Secondary accession number(s) P02593 P70667 P99014 Q13942 Q53S29 Q61379 Q61380 Q96HK3
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 111)
Name and origin of the protein
DescriptionRecName: Full=Calmodulin; Short=CaM;
Gene nameName=CALM1
Synonyms=CALM, CAM, CAM1
   and
Name=CALM2
Synonyms=CAM2, CAMB
   and
Name=CALM3
Synonyms=CALML2, CAM3, CAMC, CAMIII
Encoded onName=CALM1; Synonyms=CALM, CAM, CAM1; and Name=CALM2; Synonyms=CAM2, CAMB; and Name=CALM3; Synonyms=CALML2, CAM3, CAMC, CAMIII
Keywords3D-structure; Acetylation; Calcium; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Isopeptide bond; Methylation; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLJ04046; AAA51918.1; -; mRNA
EMBLM19311; AAA35641.1; -; mRNA
EMBLM27319; AAA35635.1; -; mRNA
EMBLX52606; CAA36839.1; ALT_SEQ; Genomic_DNA
EMBLX52607; CAA36839.1; JOINED; Genomic_DNA
EMBLX52608; CAA36839.1; JOINED; Genomic_DNA
EMBLU12022; AAB60644.1; -; Genomic_DNA
EMBLU11886; AAB60644.1; JOINED; Genomic_DNA
EMBLD45887; BAA08302.1; -; mRNA
EMBLU94728; AAC83174.1; -; Genomic_DNA
EMBLU94725; AAC83174.1; JOINED; Genomic_DNA
EMBLU94726; AAC83174.1; JOINED; Genomic_DNA
EMBLBT006818; AAP35464.1; -; mRNA
EMBLBT006855; AAP35501.1; -; mRNA
EMBLBT009916; AAP88918.1; -; mRNA
EMBLCR541990; CAG46787.1; -; mRNA
EMBLCR542021; CAG46818.1; -; mRNA
EMBLAC006536; AAD45181.1; -; Genomic_DNA
EMBLAC073283; AAY24085.1; -; Genomic_DNA
EMBLBC000454; AAH00454.1; -; mRNA
EMBLBC003354; AAH03354.1; -; mRNA
EMBLBC005137; AAH05137.1; -; mRNA
EMBLBC006464; AAH06464.1; -; mRNA
EMBLBC008437; AAH08437.1; -; mRNA
EMBLBC008597; AAH08597.1; -; mRNA
EMBLBC011834; AAH11834.1; -; mRNA
EMBLBC017385; AAH17385.1; -; mRNA
EMBLBC018677; AAH18677.1; -; mRNA
EMBLBC026065; AAH26065.1; -; mRNA
EMBLBC047523; -; NOT_ANNOTATED_CDS; mRNA
IPIIPI00075248; -; .
PIRS48728; MCHU; .
RefSeqNP_001734.1; NM_001743.4; .
RefSeqNP_005175.2; NM_005184.2; .
RefSeqNP_008819.1; NM_006888.4; .
UniGeneHs.282410; -; .
UniGeneHs.468442; -; .
UniGeneHs.515487; -; .
UniGeneHs.706125; -; .
UniGeneHs.722012; -; .
PDB1AJI; Model; -; A=5-148
PDB1CDL; X-ray; 2.00 A; A/B/C/D=2-147
PDB1CLL; X-ray; 1.70 A; A=2-149
PDB1CTR; X-ray; 2.45 A; A=2-149
PDB1IWQ; X-ray; 2.00 A; A=2-149
PDB1J7O; NMR; -; A=2-77
PDB1J7P; NMR; -; A=83-149
PDB1K90; X-ray; 2.75 A; D/E/F=2-149
PDB1K93; X-ray; 2.95 A; D/E/F=6-149
PDB1L7Z; X-ray; 2.30 A; A=2-148
PDB1LVC; X-ray; 3.60 A; D/E/F=1-149
PDB1NKF; NMR; -; A=94-105
PDB1PK0; X-ray; 3.30 A; D/E/F=2-147
PDB1S26; X-ray; 3.00 A; D/E/F=2-148
PDB1SK6; X-ray; 3.20 A; D/E/F=2-149
PDB1SW8; NMR; -; A=2-80
PDB1WRZ; X-ray; 2.00 A; A=1-149
PDB1XFU; X-ray; 3.35 A; O/P/Q/R/S/T=1-149
PDB1XFV; X-ray; 3.35 A; O/P/Q/R/S/T=1-149
PDB1XFW; X-ray; 3.40 A; O/P/Q/R/S/T=1-149
PDB1XFX; X-ray; 3.20 A; O/P/Q/R/S/T=1-149
PDB1XFY; X-ray; 3.30 A; O/P/Q/R/S/T=1-149
PDB1XFZ; X-ray; 3.25 A; O/P/Q/R/S/T=1-149
PDB1Y6W; X-ray; 2.40 A; A=2-148
PDB1YR5; X-ray; 1.70 A; A=2-148
PDB1YRT; X-ray; 2.10 A; B=76-148
PDB1YRU; X-ray; 2.50 A; B=76-148
PDB1ZOT; X-ray; 2.20 A; B=80-148
PDB1ZUZ; X-ray; 1.91 A; A=1-148
PDB2BE6; X-ray; 2.00 A; A/B/C=1-149
PDB2F3Y; X-ray; 1.45 A; A=2-148
PDB2F3Z; X-ray; 1.60 A; A=2-148
PDB2HF5; NMR; -; A=47-113
PDB2I08; X-ray; 2.00 A; A=3-78
PDB2JZI; NMR; -; A=2-149
PDB2K0E; NMR; -; A=2-149
PDB2K0F; NMR; -; A=2-149
PDB2K0J; NMR; -; A=2-149
PDB2K61; NMR; -; A=2-149
PDB2KNE; NMR; -; A=2-149
PDB2KUG; NMR; -; A=2-77
PDB2KUH; NMR; -; A=83-149
PDB2L53; NMR; -; A=2-149
PDB2L7L; NMR; -; A=2-149
PDB2R28; X-ray; 1.86 A; A/B=1-149
PDB2V01; X-ray; 2.15 A; A=1-149
PDB2V02; X-ray; 2.20 A; A=1-149
PDB2VAY; X-ray; 1.94 A; A=4-148
PDB2W73; X-ray; 1.45 A; A/B/E/F=1-149
PDB2WEL; X-ray; 1.90 A; D=1-149
PDB2X0G; X-ray; 2.20 A; B=2-149
PDB3BYA; X-ray; 1.85 A; A=2-149
PDB3DVE; X-ray; 2.35 A; A=2-149
PDB3DVJ; X-ray; 2.80 A; A=2-149
PDB3DVK; X-ray; 2.30 A; A=2-149
PDB3DVM; X-ray; 2.60 A; A=2-149
PDB3EWT; X-ray; 2.40 A; A=2-149
PDB3EWV; X-ray; 2.60 A; A=2-149
PDB3G43; X-ray; 2.10 A; A/B/C/D=2-149
PDB3HR4; X-ray; 2.50 A; B/D/F/H=1-149
PDB3O77; X-ray; 2.35 A; A=3-149
PDB3O78; X-ray; 2.60 A; A/B=3-149
PDB3OXQ; X-ray; 2.55 A; A/B/C/D=1-149
PDBsum1AJI; -; .
PDBsum1CDL; -; .
PDBsum1CLL; -; .
PDBsum1CTR; -; .
PDBsum1IWQ; -; .
PDBsum1J7O; -; .
PDBsum1J7P; -; .
PDBsum1K90; -; .
PDBsum1K93; -; .
PDBsum1L7Z; -; .
PDBsum1LVC; -; .
PDBsum1NKF; -; .
PDBsum1PK0; -; .
PDBsum1S26; -; .
PDBsum1SK6; -; .
PDBsum1SW8; -; .
PDBsum1WRZ; -; .
PDBsum1XFU; -; .
PDBsum1XFV; -; .
PDBsum1XFW; -; .
PDBsum1XFX; -; .
PDBsum1XFY; -; .
PDBsum1XFZ; -; .
PDBsum1Y6W; -; .
PDBsum1YR5; -; .
PDBsum1YRT; -; .
PDBsum1YRU; -; .
PDBsum1ZOT; -; .
PDBsum1ZUZ; -; .
PDBsum2BE6; -; .
PDBsum2F3Y; -; .
PDBsum2F3Z; -; .
PDBsum2HF5; -; .
PDBsum2I08; -; .
PDBsum2JZI; -; .
PDBsum2K0E; -; .
PDBsum2K0F; -; .
PDBsum2K0J; -; .
PDBsum2K61; -; .
PDBsum2KNE; -; .
PDBsum2KUG; -; .
PDBsum2KUH; -; .
PDBsum2L53; -; .
PDBsum2L7L; -; .
PDBsum2R28; -; .
PDBsum2V01; -; .
PDBsum2V02; -; .
PDBsum2VAY; -; .
PDBsum2W73; -; .
PDBsum2WEL; -; .
PDBsum2X0G; -; .
PDBsum3BYA; -; .
PDBsum3DVE; -; .
PDBsum3DVJ; -; .
PDBsum3DVK; -; .
PDBsum3DVM; -; .
PDBsum3EWT; -; .
PDBsum3EWV; -; .
PDBsum3G43; -; .
PDBsum3HR4; -; .
PDBsum3O77; -; .
PDBsum3O78; -; .
PDBsum3OXQ; -; .
ProteinModelPortalP62158; -; .
SMRP62158; 2-148; .
DIPDIP-31794N; -; .
IntActP62158; 172; .
MINTMINT-4999725; -; .
STRINGP62158; -; .
PhosphoSiteP62158; -; .
SWISS-2DPAGEP62158; -; .
Aarhus/Ghent-2DPAGE9048; IEF; .
DOSAC-COBS-2DPAGEP62158; -; .
OGPP02593; -; .
PRIDEP62158; -; .
EnsemblENST00000272298; ENSP00000272298; ENSG00000143933; .
EnsemblENST00000291295; ENSP00000291295; ENSG00000160014; .
EnsemblENST00000356978; ENSP00000349467; ENSG00000198668; .
EnsemblENST00000391918; ENSP00000375785; ENSG00000160014; .
GeneID801; -; .
GeneID805; -; .
GeneID808; -; .
KEGGhsa:801; -; .
KEGGhsa:805; -; .
KEGGhsa:808; -; .
UCSCuc001xyl.1; human; .
CTD801; -; .
CTD805; -; .
CTD808; -; .
H-InvDBHIX0002039; -; .
H-InvDBHIX0011883; -; .
H-InvDBHIX0015255; -; .
HGNCHGNC:1442; CALM1; .
HGNCHGNC:1445; CALM2; .
HGNCHGNC:1449; CALM3; .
HPACAB007790; -; .
HPACAB018558; -; .
MIM114180; gene; .
MIM114182; gene; .
MIM114183; gene; .
neXtProtNX_P62158; -; .
eggNOGprNOG05334; -; .
HOVERGENHBG012180; -; .
InParanoidP62158; -; .
OMAFLALMSR; -; .
OrthoDBEOG4001KK; -; .
PhylomeDBP62158; -; .
BioCycMetaCyc:ENSG00000143933-MONOMER; -; .
Pathway_Interaction_DBbcr_5pathway; BCR signaling pathway; .
Pathway_Interaction_DBnfat_tfpathway; Calcineurin-regulated NFAT-dependent transcription in lymphocytes; .
Pathway_Interaction_DBtcrcalciumpathway; Calcium signaling in the CD4+ TCR pathway; .
Pathway_Interaction_DBcd8tcrdownstreampathway; Downstream signaling in naive CD8+ T cells; .
Pathway_Interaction_DBifngpathway; IFN-gamma pathway; .
Pathway_Interaction_DBil2_pi3kpathway; IL2 signaling events mediated by PI3K; .
Pathway_Interaction_DBp38_mkk3_6pathway; p38 MAPK signaling pathway; .
Pathway_Interaction_DBsmad2_3pathway; Regulation of cytoplasmic and nuclear SMAD2/3 signaling; .
Pathway_Interaction_DBnfat_3pathway; Role of Calcineurin-dependent NFAT signaling in lymphocytes; .
Pathway_Interaction_DBvegfr1_2_pathway; Signaling events mediated by VEGFR1 and VEGFR2; .
Pathway_Interaction_DBvegfr1_pathway; VEGFR1 specific signals; .
ReactomeREACT_11061; Signalling by NGF; .
ReactomeREACT_12508; Metabolism of nitric oxide; .
ReactomeREACT_13685; Synaptic Transmission; .
ReactomeREACT_15295; Opioid Signalling; .
ReactomeREACT_17044; Muscle contraction; .
ReactomeREACT_474; Metabolism of carbohydrates; .
ReactomeREACT_604; Hemostasis; .
DrugBankDB01429; Aprindine; .
DrugBankDB01244; Bepridil; .
DrugBankDB00527; Dibucaine; .
DrugBankDB01023; Felodipine; .
DrugBankDB04841; Flunarizine; .
DrugBankDB00623; Fluphenazine; .
DrugBankDB00753; Isoflurane; .
DrugBankDB00836; Loperamide; .
DrugBankDB01110; Miconazole; .
DrugBankDB00850; Perphenazine; .
DrugBankDB00925; Phenoxybenzamine; .
DrugBankDB01100; Pimozide; .
DrugBankDB01069; Promethazine; .
NextBio3264; -; .
ArrayExpressP62158; -; .
BgeeP62158; -; .
CleanExHS_CALM1; -; .
CleanExHS_CALM2; -; .
GenevestigatorP62158; -; .
GermOnlineENSG00000143933; Homo sapiens; .
GermOnlineENSG00000160014; Homo sapiens; .
GermOnlineENSG00000198668; Homo sapiens; .
GOGO:0005813; C:centrosome; IDA:UniProtKB; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0005886; C:plasma membrane; TAS:UniProtKB; .
GOGO:0005876; C:spindle microtubule; IDA:UniProtKB; .
GOGO:0000922; C:spindle pole; IDA:UniProtKB; .
GOGO:0005509; F:calcium ion binding; IDA:BHF-UCL; .
GOGO:0031997; F:N-terminal myristoylation domain binding; IPI:UniProtKB; .
GOGO:0043274; F:phospholipase binding; IPI:BHF-UCL; .
GOGO:0019904; F:protein domain specific binding; IPI:UniProtKB; .
GOGO:0031996; F:thioesterase binding; IPI:UniProtKB; .
GOGO:0031432; F:titin binding; IPI:BHF-UCL; .
GOGO:0007202; P:activation of phospholipase C activity; TAS:Reactome; .
GOGO:0007186; P:G-protein coupled receptor protein signaling pathway; TAS:UniProtKB; .
GOGO:0006006; P:glucose metabolic process; TAS:Reactome; .
GOGO:0005980; P:glycogen catabolic process; TAS:Reactome; .
GOGO:0006936; P:muscle contraction; TAS:Reactome; .
GOGO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL; .
GOGO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome; .
GOGO:0046209; P:nitric oxide metabolic process; TAS:Reactome; .
GOGO:0030168; P:platelet activation; TAS:Reactome; .
GOGO:0002576; P:platelet degranulation; TAS:Reactome; .
GOGO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL; .
GOGO:0032465; P:regulation of cytokinesis; IMP:UniProtKB; .
GOGO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome; .
GOGO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL; .
GOGO:0051592; P:response to calcium ion; IDA:BHF-UCL; .
GOGO:0007268; P:synaptic transmission; TAS:Reactome; .
InterProIPR018248; EF-hand; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
InterProIPR001125; Recoverin; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 2; .
PfamPF00036; efhand; 4; .
PRINTSPR00450; RECOVERIN; .
SMARTSM00054; EFh; 4; .
PROSITEPS00018; EF_HAND_1; 4; .
PROSITEPS50222; EF_HAND_2; 4; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server