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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: PEBP1_HUMAN




SWISS-2DPAGE:  PEBP1_HUMAN


PEBP1_HUMAN


General information about the entry
View entry in simple text format
Entry namePEBP1_HUMAN
Primary accession numberP30086
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMarch 31, 2004 (version 3)
General Annotations were last modified on May 19, 2011 (version 13)
Name and origin of the protein
DescriptionRecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=HCNPpp; AltName: Full=Neuropolypeptide h3; AltName: Full=Prostatic-binding protein; AltName: Full=Raf kinase inhibitor protein; Short=RKIP; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;.
Gene nameName=PEBP1
Synonyms=PBP, PEBP
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, ExPASy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
[3]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
[4]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=6.96; Mw=21465  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [3].



HEPG2_HUMAN {HepG2}
Homo sapiens (Human)
Tissue: Hepatoblastoma
HEPG2_HUMAN
  map experimental info
  protein estimated location
 
HEPG2_HUMAN

MAP LOCATIONS:
pI=7.07; Mw=20738

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=7.34; Mw=20809

MAPPING (identification):
MICROSEQUENCING [1].



LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=7.76; Mw=21614  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [4].



U937_HUMAN {Macrophage Like Cell Line}
Homo sapiens (Human)
Tissue: Histiocytic lymphoma
U937_HUMAN
  map experimental info
  protein estimated location
 
U937_HUMAN

MAP LOCATIONS:
pI=7.36; Mw=19612

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
DOSAC-COBS 2D-PAGEP30086; P30086.
DOSAC-COBS-2DPAGEP30086; PEBP1_HUMAN.
OGP-WWWP30086.
REPRODUCTION-2DPAGEP30086; P30086.
REPRODUCTION-2DPAGEIPI00219446; IPI00219446.
Siena-2DPAGEP30086; PEBP1_HUMAN.
UCD-2DPAGEP30086; PEBP1_HUMAN.
UniProtKB/Swiss-ProtP30086; PEBP1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePEBP1_HUMAN
Primary accession numberP30086
Secondary accession number(s) B2R4S1
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 126)
Name and origin of the protein
DescriptionRecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=HCNPpp; AltName: Full=Neuropolypeptide h3; AltName: Full=Prostatic-binding protein; AltName: Full=Raf kinase inhibitor protein; Short=RKIP; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;
Gene nameName=PEBP1
Synonyms=PBP, PEBP
Encoded onName=PEBP1; Synonyms=PBP, PEBP
Keywords3D-structure; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Lipid-binding; Nucleotide-binding; Phosphoprotein; Protease inhibitor; Reference proteome; Serine protease inhibitor.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD16111; BAA03684.1; -; mRNA
EMBLX75252; CAA53031.1; -; mRNA
EMBLX85033; CAA59404.1; -; mRNA
EMBLAK311927; BAG34868.1; -; mRNA
EMBLCH471054; EAW98122.1; -; Genomic_DNA
EMBLBC008714; AAH08714.1; -; mRNA
EMBLBC017396; AAH17396.1; -; mRNA
EMBLBC031102; AAH31102.1; -; mRNA
EMBLS76773; AAD14234.1; -; mRNA
IPIIPI00219446; -; .
PIRI53745; I53745; .
RefSeqNP_002558.1; NM_002567.2; .
UniGeneHs.433863; -; .
PDB1BD9; X-ray; 2.05 A; A/B=1-187
PDB1BEH; X-ray; 1.75 A; A/B=1-187
PDB2QYQ; X-ray; 1.95 A; A=1-187
PDBsum1BD9; -; .
PDBsum1BEH; -; .
PDBsum2QYQ; -; .
ProteinModelPortalP30086; -; .
SMRP30086; 3-186; .
IntActP30086; 4; .
MINTMINT-5002544; -; .
STRINGP30086; -; .
MEROPSI51.002; -; .
PhosphoSiteP30086; -; .
SWISS-2DPAGEP30086; -; .
DOSAC-COBS-2DPAGEP30086; -; .
OGPP30086; -; .
REPRODUCTION-2DPAGEIPI00219446; -; .
REPRODUCTION-2DPAGEP30086; -; .
Siena-2DPAGEP30086; -; .
UCD-2DPAGEP30086; -; .
PeptideAtlasP30086; -; .
PRIDEP30086; -; .
EnsemblENST00000261313; ENSP00000261313; ENSG00000089220; .
GeneID5037; -; .
KEGGhsa:5037; -; .
UCSCuc001twu.1; human; .
CTD5037; -; .
GeneCardsGC12P115583; -; .
H-InvDBHIX0011046; -; .
HGNCHGNC:8630; PEBP1; .
HPACAB009906; -; .
HPACAB013493; -; .
HPAHPA008819; -; .
MIM604591; gene; .
neXtProtNX_P30086; -; .
PharmGKBPA32968; -; .
eggNOGprNOG19248; -; .
GeneTreeENSGT00530000063241; -; .
HOGENOMHBG588979; -; .
HOVERGENHBG008165; -; .
InParanoidP30086; -; .
OMANDVSSGC; -; .
OrthoDBEOG4FFD2T; -; .
PhylomeDBP30086; -; .
Pathway_Interaction_DBaurora_b_pathway; Aurora B signaling; .
NextBio19408; -; .
ArrayExpressP30086; -; .
BgeeP30086; -; .
CleanExHS_PEBP1; -; .
GenevestigatorP30086; -; .
GermOnlineENSG00000089220; Homo sapiens; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0008429; F:phosphatidylethanolamine binding; TAS:ProtInc; .
GOGO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW; .
InterProIPR001858; Phosphotidylethanolamine-bd_CS; .
InterProIPR008914; PtdEtn-bd_prot_PEBP; .
Gene3DG3DSA:3.90.280.10; PEBP; 1; .
PfamPF01161; PBP; 1; .
SUPFAMSSF49777; PEBP; 1; .
PROSITEPS01220; PBP; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server