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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: PRP19_HUMAN




SWISS-2DPAGE:  PRP19_HUMAN


PRP19_HUMAN


General information about the entry
View entry in simple text format
Entry namePRP19_HUMAN
Primary accession numberQ9UMS4
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onDecember 30, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Pre-mRNA-processing factor 19; AltName: Full=Nuclear matrix protein 200; AltName: Full=PRP19/PSO4 homolog; Short=hPso4; AltName: Full=Senescence evasion factor;.
Gene nameName=PRPF19
Synonyms=NMP200, PRP19, SNEV
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=56716  [identification data]
Mw=55139  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].



NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=6.67; Mw=55941  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
REPRODUCTION-2DPAGEIPI00004968; IPI00004968.
UniProtKB/Swiss-ProtQ9UMS4; PRP19_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRP19_HUMAN
Primary accession numberQ9UMS4
Sequence was last modified on May 1, 2000 (version 1)
Annotations were last modified on October 19, 2011 (version 97)
Name and origin of the protein
DescriptionRecName: Full=Pre-mRNA-processing factor 19; AltName: Full=Nuclear matrix protein 200; AltName: Full=PRP19/PSO4 homolog; Short=hPso4; AltName: Full=Senescence evasion factor;
Gene nameName=PRPF19
Synonyms=NMP200, PRP19, SNEV
Encoded onName=PRPF19; Synonyms=NMP200, PRP19, SNEV
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; DNA damage; DNA repair; DNA-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Spliceosome; WD repeat.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAJ131186; CAB51857.1; -; mRNA
EMBLBC008719; AAH08719.1; -; mRNA
EMBLBC018665; AAH18665.1; -; mRNA
EMBLBC018698; AAH18698.1; -; mRNA
IPIIPI00004968; -; .
RefSeqNP_055317.1; NM_014502.4; .
UniGeneHs.502705; -; .
ProteinModelPortalQ9UMS4; -; .
SMRQ9UMS4; 2-58; 222-504; .
IntActQ9UMS4; 8; .
MINTMINT-1454442; -; .
STRINGQ9UMS4; -; .
PhosphoSiteQ9UMS4; -; .
SWISS-2DPAGEQ9UMS4; -; .
REPRODUCTION-2DPAGEIPI00004968; -; .
PeptideAtlasQ9UMS4; -; .
PRIDEQ9UMS4; -; .
EnsemblENST00000227524; ENSP00000227524; ENSG00000110107; .
GeneID27339; -; .
KEGGhsa:27339; -; .
UCSCuc001nqf.1; human; .
CTD27339; -; .
GeneCardsGC11M057004; -; .
H-InvDBHIX0009675; -; .
HGNCHGNC:17896; PRPF19; .
HPACAB012448; -; .
MIM608330; gene; .
neXtProtNX_Q9UMS4; -; .
PharmGKBPA134941355; -; .
eggNOGprNOG18632; -; .
GeneTreeENSGT00600000084507; -; .
HOGENOMHBG315290; -; .
HOVERGENHBG053697; -; .
InParanoidQ9UMS4; -; .
OMAKMLQDEW; -; .
OrthoDBEOG4V6ZGG; -; .
PhylomeDBQ9UMS4; -; .
NextBio50404; -; .
ArrayExpressQ9UMS4; -; .
BgeeQ9UMS4; -; .
CleanExHS_PRPF19; -; .
GenevestigatorQ9UMS4; -; .
GermOnlineENSG00000110107; Homo sapiens; .
GOGO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; .
GOGO:0016607; C:nuclear speck; IDA:BHF-UCL; .
GOGO:0005819; C:spindle; IEA:UniProtKB-SubCell; .
GOGO:0000151; C:ubiquitin ligase complex; IEA:InterPro; .
GOGO:0003677; F:DNA binding; IEA:UniProtKB-KW; .
GOGO:0042802; F:identical protein binding; IPI:BHF-UCL; .
GOGO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI; .
GOGO:0006281; P:DNA repair; IEA:UniProtKB-KW; .
GOGO:0000209; P:protein polyubiquitination; IDA:MGI; .
GOGO:0000245; P:spliceosome assembly; IMP:BHF-UCL; .
InterProIPR020472; G-protein_beta_WD-40_rep; .
InterProIPR013915; Pre-mRNA_splic_Prp19; .
InterProIPR000772; Ricin_B_lectin; .
InterProIPR003613; Ubox_domain; .
InterProIPR015943; WD40/YVTN_repeat-like_dom; .
InterProIPR001680; WD40_repeat; .
InterProIPR011046; WD40_repeat-like_dom; .
InterProIPR019782; WD40_repeat_2; .
InterProIPR019775; WD40_repeat_CS; .
InterProIPR017986; WD40_repeat_dom; .
InterProIPR019781; WD40_repeat_subgr; .
InterProIPR013083; Znf_RING/FYVE/PHD; .
Gene3DG3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1; .
Gene3DG3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1; .
PfamPF08606; Prp19; 1; .
PfamPF04564; U-box; 1; .
PfamPF00400; WD40; 6; .
PRINTSPR00320; GPROTEINBRPT; .
SMARTSM00504; Ubox; 1; .
SMARTSM00320; WD40; 7; .
SUPFAMSSF50978; WD40_like; 1; .
PROSITEPS00678; WD_REPEATS_1; 1; .
PROSITEPS50082; WD_REPEATS_2; 4; .
PROSITEPS50294; WD_REPEATS_REGION; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server