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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: ROA2_HUMAN




SWISS-2DPAGE:  ROA2_HUMAN


ROA2_HUMAN


General information about the entry
View entry in simple text format
Entry nameROA2_HUMAN
Primary accession numberP22626
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1; Short=hnRNP A2/B1;.
Gene nameName=HNRNPA2B1
Synonyms=HNRPA2B1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=36076  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].



LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=7.86; Mw=34149  [identification data]
pI=8.02; Mw=34002  [identification data]
pI=8.23; Mw=34075  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
REPRODUCTION-2DPAGEP22626; P22626.
REPRODUCTION-2DPAGEIPI00414696; IPI00414696.
REPRODUCTION-2DPAGEIPI00396378; IPI00396378.
Siena-2DPAGEP22626; ROA2_HUMAN.
UCD-2DPAGEP22626; ROA2_HUMAN.
UniProtKB/Swiss-ProtP22626; ROA2_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameROA2_HUMAN
Primary accession numberP22626
Secondary accession number(s) A8K064 P22627 Q9UC98 Q9UDJ2
Sequence was last modified on November 1, 1991 (version 2)
Annotations were last modified on October 19, 2011 (version 134)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1; Short=hnRNP A2/B1;
Gene nameName=HNRNPA2B1
Synonyms=HNRPA2B1
Encoded onName=HNRNPA2B1; Synonyms=HNRPA2B1
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding; Spliceosome.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM29064; AAA60271.1; -; mRNA
EMBLM29065; AAA36574.1; -; mRNA
EMBLU09123; AAB60650.1; -; Genomic_DNA
EMBLU09120; AAB60650.1; JOINED; Genomic_DNA
EMBLU09121; AAB60650.1; JOINED; Genomic_DNA
EMBLU09122; AAB60650.1; JOINED; Genomic_DNA
EMBLD28877; BAA06031.1; -; Genomic_DNA
EMBLD28877; BAA06032.1; -; Genomic_DNA
EMBLAK289429; BAF82118.1; -; mRNA
IPIIPI00396378; -; .
IPIIPI00414696; -; .
PIRA56845; B34504; .
RefSeqNP_002128.1; NM_002137.3; .
RefSeqNP_112533.1; NM_031243.2; .
UniGeneHs.487774; -; .
PDB1X4B; NMR; -; A=1-103
PDBsum1X4B; -; .
ProteinModelPortalP22626; -; .
SMRP22626; 1-193; .
IntActP22626; 32; .
MINTMINT-4998934; -; .
STRINGP22626; -; .
PhosphoSiteP22626; -; .
SWISS-2DPAGEP22626; -; .
REPRODUCTION-2DPAGEIPI00396378; -; .
REPRODUCTION-2DPAGEIPI00414696; -; .
REPRODUCTION-2DPAGEP22626; -; .
UCD-2DPAGEP22626; -; .
PRIDEP22626; -; .
EnsemblENST00000354667; ENSP00000346694; ENSG00000122566; .
EnsemblENST00000360787; ENSP00000354021; ENSG00000122566; .
GeneID3181; -; .
KEGGhsa:3181; -; .
UCSCuc003sxr.2; human; .
UCSCuc003sxs.2; human; .
CTD3181; -; .
GeneCardsGC07M026197; -; .
H-InvDBHIX0006534; -; .
HGNCHGNC:5033; HNRNPA2B1; .
HPACAB012403; -; .
HPAHPA001666; -; .
MIM600124; gene; .
neXtProtNX_P22626; -; .
PharmGKBPA162391140; -; .
eggNOGprNOG19752; -; .
GeneTreeENSGT00540000069937; -; .
HOGENOMHBG756718; -; .
HOVERGENHBG002295; -; .
OMAEMQEVQN; -; .
OrthoDBEOG4HQDKF; -; .
PhylomeDBP22626; -; .
ReactomeREACT_1675; mRNA Processing; .
ReactomeREACT_71; Gene Expression; .
NextBio12622; -; .
PMAP-CutDBP22626; -; .
ArrayExpressP22626; -; .
BgeeP22626; -; .
CleanExHS_HNRNPA2B1; -; .
GenevestigatorP22626; -; .
GermOnlineENSG00000122566; Homo sapiens; .
GOGO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; IDA:HGNC; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0003723; F:RNA binding; IDA:HGNC; .
GOGO:0043047; F:single-stranded telomeric DNA binding; IDA:HGNC; .
GOGO:0000398; P:nuclear mRNA splicing; via spliceosome; IC:UniProtKB
GOGO:0050658; P:RNA transport; IDA:HGNC; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
Gene3DG3DSA:3.30.70.330; a_b_plait_nuc_bd; 1; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
PROSITEPS50102; RRM; 2; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server