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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: S10A4_HUMAN SWISS-2DPAGE:  S10A4_HUMAN S10A4_HUMAN General information about the entry View entry in simple text format Entry name S10A4_HUMAN Primary accession number P26447 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on March 31, 2004 (version 2) General Annotations were last modified on  May 19, 2011 (version 5) Name and origin of the protein Description RecName: Full=Protein S100-A4; AltName: Full=Calvasculin; AltName: Full=Metastasin; AltName: Full=Placental calcium-binding protein; AltName: Full=Protein Mts1; AltName: Full=S100 calcium-binding protein A4;. Gene name Name=S100A4 Synonyms=CAPL, MTS1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) [2]   MAPPING ON GEL Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D. ''''''New insights into HIV lymphocyte infection'';'';'' (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004) 2D PAGE maps for identified proteins How to interpret a protein LYMPHOCYTE_HUMAN {Lymphocytes} Homo sapiens (Human) Tissue: Lymphocyte   map experimental info   protein estimated location   LYMPHOCYTE_HUMAN MAP LOCATIONS: SPOT 2D-001YGW: pI=5.42; Mw=15461   [identification data] MAPPING (identification): Peptide mass fingerprinting [2]. NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_2D_HUMAN MAP LOCATIONS: SPOT 2D-001W9G: pI=5.72; Mw=14400   [identification data] MAPPING (identification): Peptide mass fingerprinting and tandem mass spectrometry [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P26447; P26447. DOSAC-COBS-2DPAGE P26447; S10A4_HUMAN. UniProtKB/Swiss-Prot P26447; S10A4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name S10A4_HUMAN Primary accession number P26447 Secondary accession number(s) A8K7R8 D3DV46 Q6ICP8 Sequence was last modified on  August 1, 1992 (version 1) Annotations were last modified on  September 21, 2011 (version 119) Name and origin of the protein Description RecName: Full=Protein S100-A4; AltName: Full=Calvasculin; AltName: Full=Metastasin; AltName: Full=Placental calcium-binding protein; AltName: Full=Protein Mts1; AltName: Full=S100 calcium-binding protein A4; Gene name Name=S100A4 Synonyms=CAPL, MTS1 Encoded on Name=S100A4; Synonyms=CAPL, MTS1 Keywords 3D-structure; Acetylation; Calcium; Complete proteome; Direct protein sequencing; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M80563; AAA51920.1; -; mRNA EMBL Z18950; CAA79474.1; -; Genomic_DNA EMBL Z33457; CAA83880.1; -; Genomic_DNA EMBL CR450345; CAG29341.1; -; mRNA EMBL AK292083; BAF84772.1; -; mRNA EMBL BX470102; CAI14754.1; -; Genomic_DNA EMBL CH471121; EAW53310.1; -; Genomic_DNA EMBL CH471121; EAW53311.1; -; Genomic_DNA EMBL CH471121; EAW53312.1; -; Genomic_DNA EMBL CH471121; EAW53313.1; -; Genomic_DNA EMBL CH471121; EAW53314.1; -; Genomic_DNA EMBL CH471121; EAW53315.1; -; Genomic_DNA EMBL BC000838; AAH00838.1; -; mRNA EMBL BC016300; AAH16300.1; -; mRNA IPI IPI00032313; -; . PIR A48219; A48219; . RefSeq NP_002952.1; NM_002961.2; . RefSeq NP_062427.1; NM_019554.2; . UniGene Hs.654444; -; . PDB 1M31; NMR; -; A/B=1-101 PDB 2Q91; X-ray; 1.63 A; A/B=1-101 PDB 3C1V; X-ray; 1.50 A; A/B/C/D=1-101 PDB 3CGA; X-ray; 2.03 A; A/B=1-101 PDB 3KO0; X-ray; 2.30 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=1-101 PDB 3M0W; X-ray; 2.80 A; A/B/C/D/E/F/G/H/I/J=2-101 PDBsum 1M31; -; . PDBsum 2Q91; -; . PDBsum 3C1V; -; . PDBsum 3CGA; -; . PDBsum 3KO0; -; . PDBsum 3M0W; -; . ProteinModelPortal P26447; -; . SMR P26447; 2-98; . IntAct P26447; 4; . MINT MINT-1372269; -; . STRING P26447; -; . PhosphoSite P26447; -; . SWISS-2DPAGE P26447; -; . Cornea-2DPAGE P26447; -; . DOSAC-COBS-2DPAGE P26447; -; . PeptideAtlas P26447; -; . PRIDE P26447; -; . Ensembl ENST00000354332; ENSP00000346294; ENSG00000196154; . Ensembl ENST00000368714; ENSP00000357703; ENSG00000196154; . Ensembl ENST00000368715; ENSP00000357704; ENSG00000196154; . Ensembl ENST00000368716; ENSP00000357705; ENSG00000196154; . GeneID 6275; -; . KEGG hsa:6275; -; . UCSC uc001fby.1; human; . CTD 6275; -; . GeneCards GC01M124879; -; . H-InvDB HIX0001081; -; . HGNC HGNC:10494; S100A4; . HPA CAB002618; -; . HPA CAB027387; -; . HPA HPA007973; -; . MIM 114210; gene; . neXtProt NX_P26447; -; . PharmGKB PA34906; -; . eggNOG prNOG20778; -; . GeneTree ENSGT00600000084162; -; . HOGENOM HBG716817; -; . HOVERGEN HBG001479; -; . InParanoid P26447; -; . OMA NEFFEGC; -; . OrthoDB EOG4NS3D1; -; . PhylomeDB P26447; -; . NextBio 24355; -; . ArrayExpress P26447; -; . Bgee P26447; -; . CleanEx HS_S100A4; -; . Genevestigator P26447; -; . GermOnline ENSG00000196154; Homo sapiens; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0005509; F:calcium ion binding; TAS:ProtInc; . GO GO:0050786; F:RAGE receptor binding; IPI:UniProtKB; . GO GO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC; . GO GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB; . InterPro IPR011992; EF-hand-like_dom; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR018249; EF_HAND_2; . InterPro IPR001751; S100/CaBP-9k_CS; . InterPro IPR013787; S100_Ca-bd_sub; . Gene3D G3DSA:1.10.238.10; EF-Hand_type; 1; . Pfam PF01023; S_100; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 1; . PROSITE PS00303; S100_CABP; 1; . SWISS-2DPAGE (search AC)