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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: VIME_HUMAN SWISS-2DPAGE:  VIME_HUMAN VIME_HUMAN General information about the entry View entry in simple text format Entry name VIME_HUMAN Primary accession number P08670 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on March 31, 2004 (version 3) General Annotations were last modified on  May 19, 2011 (version 6) Name and origin of the protein Description RecName: Full=Vimentin;. Gene name Name=VIM Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) [2]   MAPPING ON GEL Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D. ''''''New insights into HIV lymphocyte infection'';'';'' (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001V8G: Mw=58189   [identification data] BAND 1D-001V8H: Mw=56716   [identification data] MAPPING (identification): Tandem mass spectrometry [1]. LYMPHOCYTE_HUMAN {Lymphocytes} Homo sapiens (Human) Tissue: Lymphocyte   map experimental info   protein estimated location   LYMPHOCYTE_HUMAN MAP LOCATIONS: SPOT 2D-001Y0D: pI=4.94; Mw=43308   [identification data] SPOT 2D-001Y0H: pI=4.99; Mw=43286   [identification data] SPOT 2D-001Y0I: pI=5.06; Mw=43286   [identification data] EXPRESSION: expressed predominantly in CD8 and CD4 lymphocytes [2]. MAPPING (identification): MALDI tandem mass spectrometry [2]. NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_2D_HUMAN MAP LOCATIONS: SPOT 2D-001VJV: pI=5.21; Mw=57216   [identification data] SPOT 2D-001VJW: pI=5.27; Mw=57216   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P08670; P08670. DOSAC-COBS-2DPAGE P08670; VIME_HUMAN. HSC-2DPAGE P08670; HUMAN. Lens-2DPAGE P08670. OGP-WWW P08670. PHCI-2DPAGE P08670. REPRODUCTION-2DPAGE P08670; P08670. REPRODUCTION-2DPAGE IPI00418471; IPI00418471. Siena-2DPAGE P08670; VIME_HUMAN. UCD-2DPAGE P08670; VIME_HUMAN. UniProtKB/Swiss-Prot P08670; VIME_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name VIME_HUMAN Primary accession number P08670 Secondary accession number(s) B0YJC2 D3DRU4 Q15867 Q15868 Q15869 Q548L2 Q6LER9 Q8N850 Q96ML2 Q9NTM3 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  October 19, 2011 (version 160) Name and origin of the protein Description RecName: Full=Vimentin; Gene name Name=VIM Encoded on Name=VIM Keywords 3D-structure; Acetylation; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Intermediate filament; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M14144; AAA61279.1; -; Genomic_DNA EMBL X56134; CAA39600.1; -; mRNA EMBL AF328728; AAN09720.1; -; mRNA EMBL Z19554; CAA79613.2; -; mRNA EMBL AK056766; BAB71275.1; ALT_FRAME; mRNA EMBL AK097336; BAC05002.1; -; mRNA EMBL AK290643; BAF83332.1; -; mRNA EMBL CR407690; CAG28618.1; -; mRNA EMBL AK222507; BAD96227.1; -; mRNA EMBL AK222602; BAD96322.1; -; mRNA EMBL EF445046; ACA06101.1; -; Genomic_DNA EMBL EF445046; ACA06102.1; -; Genomic_DNA EMBL AL133415; CAB87963.1; -; Genomic_DNA EMBL CH471072; EAW86215.1; -; Genomic_DNA EMBL CH471072; EAW86216.1; -; Genomic_DNA EMBL BC000163; AAH00163.2; -; mRNA EMBL BC030573; AAH30573.1; -; mRNA EMBL BC066956; AAH66956.1; -; mRNA EMBL X16478; CAA34499.1; -; mRNA EMBL M18895; AAA61281.2; -; Genomic_DNA EMBL M18888; AAA61281.2; JOINED; Genomic_DNA EMBL M18889; AAA61281.2; JOINED; Genomic_DNA EMBL M18890; AAA61281.2; JOINED; Genomic_DNA EMBL M18891; AAA61281.2; JOINED; Genomic_DNA EMBL M18892; AAA61281.2; JOINED; Genomic_DNA EMBL M18893; AAA61281.2; JOINED; Genomic_DNA EMBL M18894; AAA61281.2; JOINED; Genomic_DNA EMBL M25246; AAA61282.1; -; mRNA IPI IPI00418471; -; . PIR S13115; A25074; . RefSeq NP_003371.2; NM_003380.3; . UniGene Hs.455493; -; . PDB 1GK4; X-ray; 2.30 A; A/B/C/D/E/F=328-411 PDB 1GK6; X-ray; 1.90 A; A/B=385-412 PDB 1GK7; X-ray; 1.40 A; A=102-138 PDB 3G1E; X-ray; 1.83 A; A/B=102-138 PDB 3KLT; X-ray; 2.70 A; A/B/C/D=263-334 PDB 3OL1; X-ray; 2.81 A; A/B/C/D=144-251 PDBsum 1GK4; -; . PDBsum 1GK6; -; . PDBsum 1GK7; -; . PDBsum 3G1E; -; . PDBsum 3KLT; -; . PDBsum 3OL1; -; . ProteinModelPortal P08670; -; . SMR P08670; 101-138; 144-248; 263-406 IntAct P08670; 91; . MINT MINT-118802; -; . STRING P08670; -; . PhosphoSite P08670; -; . SWISS-2DPAGE P08670; -; . Aarhus/Ghent-2DPAGE 8417; IEF; . Cornea-2DPAGE P08670; -; . DOSAC-COBS-2DPAGE P08670; -; . OGP P08670; -; . PHCI-2DPAGE P08670; -; . REPRODUCTION-2DPAGE IPI00418471; -; . REPRODUCTION-2DPAGE P08670; -; . UCD-2DPAGE P08670; -; . PeptideAtlas P08670; -; . PRIDE P08670; -; . Ensembl ENST00000224237; ENSP00000224237; ENSG00000026025; . GeneID 7431; -; . KEGG hsa:7431; -; . UCSC uc001iou.1; human; . CTD 7431; -; . GeneCards GC10P017275; -; . H-InvDB HIX0008682; -; . H-InvDB HIX0035657; -; . HGNC HGNC:12692; VIM; . HPA CAB000080; -; . HPA HPA001762; -; . MIM 193060; gene; . neXtProt NX_P08670; -; . Orphanet 98984; Pulverulent cataract; . PharmGKB PA37311; -; . eggNOG prNOG10698; -; . HOVERGEN HBG013015; -; . InParanoid P08670; -; . OMA ANRTNEK; -; . OrthoDB EOG4GHZPD; -; . PhylomeDB P08670; -; . Pathway_Interaction_DB aurora_b_pathway; Aurora B signaling; . Pathway_Interaction_DB caspase_pathway; Caspase cascade in apoptosis; . Reactome REACT_17044; Muscle contraction; . Reactome REACT_578; Apoptosis; . NextBio 29104; -; . PMAP-CutDB P08670; -; . ArrayExpress P08670; -; . Bgee P08670; -; . Genevestigator P08670; -; . GermOnline ENSG00000026025; Homo sapiens; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0005882; C:intermediate filament; IDA:UniProtKB; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0008022; F:protein C-terminus binding; IPI:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; IDA:UniProtKB; . GO GO:0006921; P:cellular component disassembly involved in apoptosis; TAS:Reactome; . GO GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; . GO GO:0030049; P:muscle filament sliding; TAS:Reactome; . InterPro IPR016044; F; . InterPro IPR001664; IF; . InterPro IPR006821; Intermed_filament_DNA-bd; . InterPro IPR018039; Intermediate_filament_CS; . PANTHER PTHR23239; IF; 1; . Pfam PF00038; Filament; 1; . Pfam PF04732; Filament_head; 1; . PROSITE PS00226; IF; 1; . SWISS-2DPAGE (search AC)