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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P06733




SWISS-2DPAGE:  P06733


P06733


General information about the entry
View entry in simple text format
Entry nameENOA_HUMAN
Primary accession numberP06733
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Alpha-enolase; EC=4.2.1.11; AltName: Full=2-phospho-D-glycerate hydro-lyase; AltName: Full=C-myc promoter-binding protein; AltName: Full=Enolase 1; AltName: Full=MBP-1; AltName: Full=MPB-1; AltName: Full=Non-neural enolase; Short=NNE; AltName: Full=Phosphopyruvate hydratase; AltName: Full=Plasminogen-binding protein;.
Gene nameName=ENO1
Synonyms=ENO1L1, MBPB1, MPB1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
Comments
  • SUBUNIT: Homodimer
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=7.37; Mw=42232  [identification data]
pI=6.95; Mw=33854  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
DOSAC-COBS 2D-PAGEP06733; P06733.
DOSAC-COBS-2DPAGEP06733; ENOA_HUMAN.
OGP-WWWP06733.
REPRODUCTION-2DPAGEP06733; P06733.
REPRODUCTION-2DPAGEIPI00465248; IPI00465248.
Siena-2DPAGEP06733; ENOA_HUMAN.
UCD-2DPAGEP06733; ENOA_HUMAN.
UniProtKB/Swiss-ProtP06733; ENOA_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameENOA_HUMAN
Primary accession numberP06733
Secondary accession number(s) B2RD59 P22712 Q16704 Q4TUS4 Q53FT9 Q53HR3 Q658M5 Q6GMP2 Q71V37 Q7Z3V6 Q8WU71 Q9UCH6 Q9UM55
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 154)
Name and origin of the protein
DescriptionRecName: Full=Alpha-enolase; EC=4.2.1.11; AltName: Full=2-phospho-D-glycerate hydro-lyase; AltName: Full=C-myc promoter-binding protein; AltName: Full=Enolase 1; AltName: Full=MBP-1; AltName: Full=MPB-1; AltName: Full=Non-neural enolase; Short=NNE; AltName: Full=Phosphopyruvate hydratase; AltName: Full=Plasminogen-binding protein;
Gene nameName=ENO1
Synonyms=ENO1L1, MBPB1, MPB1
Encoded onName=ENO1; Synonyms=ENO1L1, MBPB1, MPB1
Keywords3D-structure; Acetylation; Alternative initiation; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Glycolysis; Lyase; Magnesium; Membrane; Metal-binding; Nucleus; Phosphoprotein; Plasminogen activation; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM14328; AAA52387.1; -; mRNA
EMBLX16288; CAA34360.1; -; Genomic_DNA
EMBLX16289; CAA34360.1; JOINED; Genomic_DNA
EMBLX16290; CAA34360.1; JOINED; Genomic_DNA
EMBLM55914; AAA35698.1; ALT_FRAME; mRNA
EMBLX84907; CAA59331.1; -; mRNA
EMBLBT007163; AAP35827.1; -; mRNA
EMBLAK315417; BAG37806.1; -; mRNA
EMBLAL833741; CAH56247.1; -; mRNA
EMBLBX537400; CAD97642.1; -; mRNA
EMBLAK222517; BAD96237.1; -; mRNA
EMBLAK223192; BAD96912.1; -; mRNA
EMBLDQ056744; AAY43128.1; -; Genomic_DNA
EMBLAL139415; CAC42425.1; -; Genomic_DNA
EMBLCH471130; EAW71604.1; -; Genomic_DNA
EMBLBC001810; AAH01810.1; -; mRNA
EMBLBC004458; AAH04458.1; -; mRNA
EMBLBC009912; AAH09912.1; -; mRNA
EMBLBC011130; AAH11130.1; -; mRNA
EMBLBC015641; AAH15641.1; -; mRNA
EMBLBC021166; AAH21166.2; -; mRNA
EMBLBC022545; AAH22545.1; -; mRNA
EMBLBC027725; AAH27725.1; -; mRNA
EMBLBC050642; AAH50642.1; -; mRNA
EMBLU88968; AAC39935.1; -; mRNA
EMBLAF035286; AAB88178.1; -; mRNA
IPIIPI00465248; -; .
IPIIPI00759806; -; .
PIRA39579; A39579; .
PIRS11696; A29170; .
RefSeqNP_001188412.1; NM_001201483.1; .
RefSeqNP_001419.1; NM_001428.3; .
UniGeneHs.517145; -; .
PDB2PSN; X-ray; 2.20 A; A/B/C/D=1-434
PDB3B97; X-ray; 2.20 A; A/B/C/D=2-434
PDBsum2PSN; -; .
PDBsum3B97; -; .
ProteinModelPortalP06733; -; .
SMRP06733; 2-434; .
IntActP06733; 14; .
MINTMINT-155303; -; .
STRINGP06733; -; .
PhosphoSiteP06733; -; .
SWISS-2DPAGEP06733; -; .
Aarhus/Ghent-2DPAGE1325; IEF; .
Aarhus/Ghent-2DPAGE5406; NEPHGE; .
Cornea-2DPAGEP06733; -; .
DOSAC-COBS-2DPAGEP06733; -; .
OGPP06733; -; .
REPRODUCTION-2DPAGEIPI00465248; -; .
REPRODUCTION-2DPAGEP06733; -; .
UCD-2DPAGEP06733; -; .
PeptideAtlasP06733; -; .
PRIDEP06733; -; .
EnsemblENST00000234590; ENSP00000234590; ENSG00000074800; .
GeneID2023; -; .
KEGGhsa:2023; -; .
UCSCuc001apj.1; human; .
CTD2023; -; .
GeneCardsGC01M008070; -; .
H-InvDBHIX0000101; -; .
HGNCHGNC:3350; ENO1; .
HPACAB018614; -; .
MIM172430; gene; .
neXtProtNX_P06733; -; .
PharmGKBPA27786; -; .
eggNOGprNOG13095; -; .
HOVERGENHBG000067; -; .
InParanoidP06733; -; .
OMAKVEIGMD; -; .
OrthoDBEOG4T783B; -; .
PhylomeDBP06733; -; .
Pathway_Interaction_DBhif1_tfpathway; HIF-1-alpha transcription factor network; .
ReactomeREACT_474; Metabolism of carbohydrates; .
NextBio8197; -; .
PMAP-CutDBP06733; -; .
ArrayExpressP06733; -; .
BgeeP06733; -; .
GenevestigatorP06733; -; .
GermOnlineENSG00000074800; Homo sapiens; .
GOGO:0005634; C:nucleus; IC:UniProtKB; .
GOGO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0030017; C:sarcomere; IEA:UniProtKB-SubCell; .
GOGO:0003677; F:DNA binding; IEA:UniProtKB-KW; .
GOGO:0000287; F:magnesium ion binding; IEA:InterPro; .
GOGO:0004634; F:phosphopyruvate hydratase activity; TAS:ProtInc; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc; .
GOGO:0003714; F:transcription corepressor activity; TAS:ProtInc; .
GOGO:0006094; P:gluconeogenesis; TAS:Reactome; .
GOGO:0006096; P:glycolysis; TAS:Reactome; .
GOGO:0030308; P:negative regulation of cell growth; IDA:UniProtKB; .
GOGO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc; .
GOGO:0009615; P:response to virus; IEP:UniProtKB; .
InterProIPR000941; Enolase; .
InterProIPR020810; Enolase_C; .
InterProIPR020809; Enolase_CS; .
InterProIPR020811; Enolase_N; .
PANTHERPTHR11902; Enolase; 1; .
PfamPF00113; Enolase_C; 1; .
PfamPF03952; Enolase_N; 1; .
PIRSFPIRSF001400; Enolase; 1; .
PRINTSPR00148; ENOLASE; .
TIGRFAMsTIGR01060; Eno; 1; .
PROSITEPS00164; ENOLASE; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server