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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0004]' for entry matching: P63086 World-2DPAGE Repository (0004):  P63086 P63086 General information about the entry View entry in simple text format Entry name MK01_RAT Primary accession number P63086 integrated into World-2DPAGE Repository (0004) on  October 13, 2008 (release 1) 2D Annotations were last modified on May 18, 2011 (version 2) General Annotations were last modified on  December 22, 2011 (version 2) Name and origin of the protein Description RecName: Full=Mitogen-activated protein kinase 1; Short=MAP kinase 1; Short=MAPK 1; EC=2.7.11.24; AltName: Full=ERT1; AltName: Full=Extracellular signal-regulated kinase 2; Short=ERK-2; AltName: Full=MAP kinase isoform p42; Short=p42-MAPK; AltName: Full=Mitogen-activated protein kinase 2; Short=MAP kinase 2; Short=MAPK 2;. Gene name Name=Mapk1 Synonyms=Erk2, Mapk, Prkm1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009) 2D PAGE maps for identified proteins How to interpret a protein OB21DSUB {2-DE gel for Olfactory bulb proteome} Rattus norvegicus (Rat) Tissue: Olfactory bulb   map experimental info   OB21DSUB MAP LOCATIONS: SPOT 450: pI=6.40; Mw=43000   [identification data] MAPPING (identification): SPOT 450: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India Cross-references UniProtKB/Swiss-Prot P63086; MK01_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_12 Entry name MK01_RAT Primary accession number P63086 Secondary accession number(s) P27703 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  December 14, 2011 (version 96) Name and origin of the protein Description RecName: Full=Mitogen-activated protein kinase 1; Short=MAP kinase 1; Short=MAPK 1; EC=2.7.11.24; AltName: Full=ERT1; AltName: Full=Extracellular signal-regulated kinase 2; Short=ERK-2; AltName: Full=MAP kinase isoform p42; Short=p42-MAPK; AltName: Full=Mitogen-activated protein kinase 2; Short=MAP kinase 2; Short=MAPK 2; Gene name Name=Mapk1 Synonyms=Erk2, Mapk, Prkm1 Encoded on Name=Mapk1; Synonyms=Erk2, Mapk, Prkm1 Keywords 3D-structure; Acetylation; ATP-binding; Cell cycle; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M64300; AAA41124.1; -; mRNA IPI IPI00199688; -; . PIR A40033; A40033; . RefSeq NP_446294.1; NM_053842.1; . UniGene Rn.34914; -; . PDB 1ERK; X-ray; 2.30 A; A=1-358 PDB 1GOL; X-ray; 2.80 A; A=1-358 PDB 2ERK; X-ray; 2.40 A; A=1-358 PDB 2FYS; X-ray; 2.50 A; A/B=2-357 PDB 2GPH; X-ray; 1.90 A; A=2-357 PDB 2Z7L; X-ray; 2.41 A; A=1-358 PDB 3C9W; X-ray; 2.50 A; A/B=2-358 PDB 3ERK; X-ray; 2.10 A; A=1-358 PDB 3O71; X-ray; 1.95 A; A=1-358 PDB 3QYW; X-ray; 1.50 A; A=1-358 PDB 3QYZ; X-ray; 1.46 A; A=1-358 PDB 3R63; X-ray; 1.70 A; A=1-358 PDB 4ERK; X-ray; 2.20 A; A=1-358 PDBsum 1ERK; -; . PDBsum 1GOL; -; . PDBsum 2ERK; -; . PDBsum 2FYS; -; . PDBsum 2GPH; -; . PDBsum 2Z7L; -; . PDBsum 3C9W; -; . PDBsum 3ERK; -; . PDBsum 3O71; -; . PDBsum 3QYW; -; . PDBsum 3QYZ; -; . PDBsum 3R63; -; . PDBsum 4ERK; -; . ProteinModelPortal P63086; -; . SMR P63086; 6-355; . DIP DIP-29117N; -; . IntAct P63086; 2; . MINT MINT-100037; -; . STRING P63086; -; . PhosphoSite P63086; -; . World-2DPAGE 0004:P63086; -; . PRIDE P63086; -; . GeneID 116590; -; . KEGG rno:116590; -; . CTD 5594; -; . RGD 70500; Mapk1; . eggNOG roNOG04134; -; . GeneTree ENSGT00550000074298; -; . HOVERGEN HBG014652; -; . InParanoid P63086; -; . OrthoDB EOG45HRXM; -; . PhylomeDB P63086; -; . BRENDA 2.7.11.24; 5301; . Reactome REACT_109781; Immune System; . Reactome REACT_111984; Signal Transduction; . Reactome REACT_112697; Developmental Biology; . NextBio 619269; -; . ArrayExpress P63086; -; . Genevestigator P63086; -; . GermOnline ENSRNOG00000001849; Rattus norvegicus; . GO GO:0033267; C:axon part; IDA:RGD; . GO GO:0005829; C:cytosol; IDA:RGD; . GO GO:0032839; C:dendrite cytoplasm; IDA:RGD; . GO GO:0005626; C:insoluble fraction; IDA:RGD; . GO GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; . GO GO:0005654; C:nucleoplasm; IDA:UniProtKB; . GO GO:0043204; C:perikaryon; IDA:RGD; . GO GO:0043234; C:protein complex; IDA:RGD; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0005524; F:ATP binding; IDA:RGD; . GO GO:0004707; F:MAP kinase activity; IDA:UniProtKB; . GO GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD; . GO GO:0008134; F:transcription factor binding; IPI:RGD; . GO GO:0007049; P:cell cycle; IEA:UniProtKB-KW; . GO GO:0000189; P:MAPK import into nucleus; IDA:RGD; . GO GO:0030335; P:positive regulation of cell migration; IEP:RGD; . GO GO:0008284; P:positive regulation of cell proliferation; IEP:RGD; . GO GO:0045893; P:positive regulation of transcription; DNA-dependent; IEP:RGD GO GO:0045727; P:positive regulation of translation; IMP:RGD; . GO GO:0043627; P:response to estrogen stimulus; IDA:RGD; . GO GO:0009636; P:response to toxin; IDA:RGD; . GO GO:0019233; P:sensory perception of pain; IMP:UniProtKB; . InterPro IPR008349; Erk_1_2_MAPK; . InterPro IPR011009; Kinase-like_dom; . InterPro IPR003527; MAP_kinase_CS; . InterPro IPR000719; Prot_kinase_cat_dom; . InterPro IPR017441; Protein_kinase_ATP_BS; . InterPro IPR017442; Se/Thr_kinase-like_dom; . InterPro IPR008271; Ser/Thr_kinase_AS; . InterPro IPR002290; Ser/Thr_kinase_dom; . KO K04371; -; . Pfam PF00069; Pkinase; 1; . PRINTS PR01770; ERK1ERK2MAPK; . SMART SM00220; S_TKc; 1; . SUPFAM SSF56112; Kinase_like; 1; . PROSITE PS01351; MAPK; 1; . PROSITE PS00107; PROTEIN_KINASE_ATP; 1; . PROSITE PS50011; PROTEIN_KINASE_DOM; 1; . PROSITE PS00108; PROTEIN_KINASE_ST; 1; . World-2DPAGE Repository (search AC)