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Searching in 'World-2DPAGE Repository [0022]' for entry matching: ACADV_RAT




World-2DPAGE Repository (0022):  ACADV_RAT


ACADV_RAT


General information about the entry
View entry in simple text format
Entry nameACADV_RAT
Primary accession numberP45953
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Short=VLCAD; EC=1.3.99.-; Flags: Precursor;.
Gene nameName=Acadvl
Synonyms=Vlcad
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=9.01; Mw=71047  [identification data]

IDENTIFICATION: SPOT 88: SeqCov=26.7%. Peptides MS=14/20. Mascot PMF Score=108 [1].
PEPTIDE EVIDENCE: SPOT 88: 557-GIVNEQFLLQR-567 (67) / 568-LADGAIDLYAMVVVLSR-584 (105) / 138-ELGAFGLQVPSELGGLGLSNTQYAR-162 (175) [1].
MAPPING (identification):
SPOT 88: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP45953; ACADV_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameACADV_RAT
Primary accession numberP45953
Sequence was last modified on November 1, 1995 (version 1)
Annotations were last modified on November 16, 2011 (version 96)
Name and origin of the protein
DescriptionRecName: Full=Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Short=VLCAD; EC=1.3.99.-; Flags: Precursor;
Gene nameName=Acadvl
Synonyms=Vlcad
Encoded onName=Acadvl; Synonyms=Vlcad
KeywordsAcetylation; Complete proteome; Direct protein sequencing; FAD; Fatty acid metabolism; Flavoprotein; Isopeptide bond; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Reference proteome; Transit peptide; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD30647; BAA06331.1; -; mRNA
IPIIPI00213057; -; .
PIRA54872; A54872; .
RefSeqNP_037023.1; NM_012891.1; .
UniGeneRn.33319; -; .
ProteinModelPortalP45953; -; .
SMRP45953; 69-653; .
STRINGP45953; -; .
PRIDEP45953; -; .
GeneID25363; -; .
KEGGrno:25363; -; .
UCSCNM_012891; rat; .
CTD37; -; .
RGD2014; Acadvl; .
eggNOGroNOG11053; -; .
HOVERGENHBG050448; -; .
InParanoidP45953; -; .
OrthoDBEOG4P5K8R; -; .
NextBio606351; -; .
ArrayExpressP45953; -; .
GenevestigatorP45953; -; .
GermOnlineENSRNOG00000018114; Rattus norvegicus; .
GOGO:0005743; C:mitochondrial inner membrane; IDA:RGD; .
GOGO:0000062; F:fatty-acyl-CoA binding; IDA:RGD; .
GOGO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD; .
GOGO:0004466; F:long-chain-acyl-CoA dehydrogenase activity; IDA:RGD; .
GOGO:0017099; F:very long-chain-acyl-CoA dehydrogenase activity; IDA:RGD; .
GOGO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IMP:RGD; .
GOGO:0042760; P:very long-chain fatty acid catabolic process; IMP:RGD; .
InterProIPR006089; Acyl-CoA_DH_CS; .
InterProIPR006092; Acyl-CoA_DH_N; .
InterProIPR006090; Acyl-CoA_Oxase/DH_1; .
InterProIPR006091; Acyl-CoA_Oxase/DH_cen-dom; .
InterProIPR009075; AcylCo_DH/oxidase_C; .
InterProIPR013786; AcylCoA_DH/ox_N; .
InterProIPR009100; AcylCoA_DH/oxidase; .
Gene3DG3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1; .
Gene3DG3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1; .
Gene3DG3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 1; .
KOK09479; -; .
PfamPF00441; Acyl-CoA_dh_1; 1; .
PfamPF02770; Acyl-CoA_dh_M; 1; .
PfamPF02771; Acyl-CoA_dh_N; 1; .
SUPFAMSSF56645; AcylCoA_dehyd_NM; 1; .
SUPFAMSSF47203; AcylCoADH_C_like; 1; .
PROSITEPS00072; ACYL_COA_DH_1; 1; .
PROSITEPS00073; ACYL_COA_DH_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server