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Searching in 'World-2DPAGE Repository [0014]' for entry matching: ACOC_RAT




World-2DPAGE Repository (0014):  ACOC_RAT

ACOC_RAT


General information about the entry
View entry in simple text format
Entry nameACOC_RAT
Primary accession numberQ63270
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Cytoplasmic aconitate hydratase; Short=Aconitase; EC=4.2.1.3; AltName: Full=Citrate hydro-lyase; AltName: Full=Iron regulatory protein 1; Short=IRP1; AltName: Full=Iron-responsive element-binding protein 1; Short=IRE-BP 1;.
Gene nameName=Aco1
Synonyms=Ireb1, Irebp
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.200900680;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
RAT_CEREBELLUM_21D
  map experimental info 		 
RAT_CEREBELLUM_21D

MAP LOCATIONS:
pI=7.73; Mw=76000  [identification data]

IDENTIFICATION: SPOT 2706: SeqCov=26%. MascotPMF=112 [1].
MAPPING (identification):
SPOT 2706: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE10017.
UniProtKB/Swiss-ProtQ63270; ACOC_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameACOC_RAT
Primary accession numberQ63270
Sequence was last modified on November 1, 1996 (version 1)
Annotations were last modified on November 16, 2011 (version 97)
Name and origin of the protein
DescriptionRecName: Full=Cytoplasmic aconitate hydratase; Short=Aconitase; EC=4.2.1.3; AltName: Full=Citrate hydro-lyase; AltName: Full=Iron regulatory protein 1; Short=IRP1; AltName: Full=Iron-responsive element-binding protein 1; Short=IRE-BP 1;
Gene nameName=Aco1
Synonyms=Ireb1, Irebp
Encoded onName=Aco1; Synonyms=Ireb1, Irebp
Keywords4Fe-4S; Complete proteome; Cytoplasm; Direct protein sequencing; Iron; Iron-sulfur; Lyase; Metal-binding; Reference proteome; RNA-binding; Tricarboxylic acid cycle.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLL23874; AAA41449.1; -; mRNA
IPIIPI00207003; -; .
PIRA44154; A44154; .
RefSeqNP_059017.1; NM_017321.1; .
UniGeneRn.35934; -; .
ProteinModelPortalQ63270; -; .
SMRQ63270; 3-889; .
STRINGQ63270; -; .
PhosphoSiteQ63270; -; .
PRIDEQ63270; -; .
GeneID50655; -; .
KEGGrno:50655; -; .
UCSCNM_017321; rat; .
CTD48; -; .
RGD2019; Aco1; .
eggNOGroNOG06028; -; .
GeneTreeENSGT00530000063060; -; .
HOVERGENHBG052147; -; .
OrthoDBEOG4C2H8W; -; .
PhylomeDBQ63270; -; .
NextBio610466; -; .
ArrayExpressQ63270; -; .
GenevestigatorQ63270; -; .
GermOnlineENSRNOG00000005849; Rattus norvegicus; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005783; C:endoplasmic reticulum; IDA:RGD; .
GOGO:0005794; C:Golgi apparatus; IDA:MGI; .
GOGO:0005792; C:microsome; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0051539; F:4 iron; 4 sulfur cluster binding; ISS:UniProtKB
GOGO:0003994; F:aconitate hydratase activity; ISS:UniProtKB; .
GOGO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GOGO:0030350; F:iron-responsive element binding; ISS:UniProtKB; .
GOGO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0048027; F:mRNA 5'-UTR binding; IDA:RGD; .
GOGO:0006879; P:cellular iron ion homeostasis; IDA:RGD; .
GOGO:0006101; P:citrate metabolic process; ISS:UniProtKB; .
GOGO:0006417; P:regulation of translation; TAS:RGD; .
GOGO:0010040; P:response to iron(II) ion; ISS:UniProtKB; .
GOGO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW; .
InterProIPR015931; Acnase/IPM_dHydase_lsu_aba_1/3; .
InterProIPR015937; Acoase/IPM_deHydtase; .
InterProIPR001030; Acoase/IPM_deHydtase_lsu_aba; .
InterProIPR015928; Aconitase/3IPM_dehydase_swvl; .
InterProIPR006249; Aconitase/Fe_reg_prot_2; .
InterProIPR015934; Aconitase/Fe_reg_prot_2/AcnD; .
InterProIPR015932; Aconitase/IPMdHydase_lsu_aba_2; .
InterProIPR018136; Aconitase_4Fe-4S_BS; .
InterProIPR000573; AconitaseA/IPMdHydase_ssu_swvl; .
Gene3DG3DSA:3.30.499.10; Acnase/IPM_dHydase_lsu_aba_1/3; 3; .
Gene3DG3DSA:3.20.19.10; Aconitase/3IPM_dehydase_swvl; 1; .
Gene3DG3DSA:3.40.1060.10; Aconitase/IPMdHydase_lsu_aba_2; 1; .
KOK01681; -; .
PANTHERPTHR11670; Aconitase-like_core; 1; .
PANTHERPTHR11670:SF1; Aconitase/Fe_reg_prot_2/AcnD; 1; .
PfamPF00330; Aconitase; 1; .
PfamPF00694; Aconitase_C; 1; .
PRINTSPR00415; ACONITASE; .
SUPFAMSSF52016; Aconitase/3IPM_dehydase_swvl; 1; .
SUPFAMSSF53732; Aconitase_N; 1; .
TIGRFAMsTIGR01341; Aconitase_1; 1; .
PROSITEPS00450; ACONITASE_1; 1; .
PROSITEPS01244; ACONITASE_2; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server