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World-2DPAGE Repository
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Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0022]' for entry
matching:
ACTC_RAT
World-2DPAGE Repository
(0022):
ACTC_RAT
ACTC_RAT
General information about the entry
View entry in simple text format
Entry name
ACTC_RAT
Primary accession number
P68035
integrated into World-2DPAGE Repository (0022) on
May 7, 2010 (release 1)
2D Annotations were last modified on
June 22, 2011 (version 2)
General Annotations were last modified on
November 24, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Actin, alpha cardiac muscle 1; AltName: Full=Alpha-cardiac actin; Flags: Precursor;.
Gene name
Name=Actc1
Synonyms=Actc
Annotated species
Rattus [TaxID:
10114
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.201000593
;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein
HCR_LCR_HEART
{HCR LCR Cardiac Map}
Rattus
Tissue: Heart
map experimental info
HCR_LCR_HEART
MAP LOCATIONS:
SPOT 418
:
pI=5.23; Mw=42334
[identification data]
SPOT 467
:
pI=5.23; Mw=42334
[identification data]
SPOT 531
:
pI=5.23; Mw=42334
[identification data]
SPOT 736
:
pI=5.23; Mw=42334
[identification data]
SPOT 879
:
pI=5.23; Mw=42334
[identification data]
IDENTIFICATION:
SPOT 418: SeqCov=30%. Peptides MS=11/20. Mascot PMF Score=107 [
1
]
SPOT 467: SeqCov=20.7%. Peptides MS=7/20. Mascot PMF Score=53 [
1
]; SPOT 531: SeqCov=28.6%. Peptides MS=9/20. Mascot PMF Score=80 [
1
]; SPOT 736: SeqCov=32.1%. Peptides MS=12/20. Mascot PMF Score=122 [
1
]; SPOT 879: SeqCov=30%. Peptides MS=11/20. Mascot PMF Score=107 [
1
].
PEPTIDE EVIDENCE:
SPOT 418: 329-IIAPPER-335 (24) / 85-IWHHTFYNELR-95 (79) / 239-SYELPDGQVITIGNER-254 (88) [
1
]
SPOT 467: 329-IIAPPER-335 (21) / 85-IWHHTFYNELR-95 (74) / 239-SYELPDGQVITIGNER-254 (111) [
1
]; SPOT 531: 329-IIAPPER-335 (14) / 85-IWHHTFYNELR-95 (71) / 239-SYELPDGQVITIGNER-254 (62) [
1
]; SPOT 879: 329-IIAPPER-335 (35) / 85-IWHHTFYNELR-95 (66) / 239-SYELPDGQVITIGNER-254 (103) [
1
].
MAPPING (identification):
SPOT
418
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
467
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
531
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
736
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
879
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-Prot
P68035; ACTC_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
ACTC_RAT
Primary accession number
P68035
Secondary accession number(s)
A0JPJ4 P04270
Sequence was last modified on
March 20, 1987 (version 1)
Annotations were last modified on
November 16, 2011 (version 60)
Name and origin of the protein
Description
RecName: Full=Actin, alpha cardiac muscle 1; AltName: Full=Alpha-cardiac actin; Flags: Precursor;
Gene name
Name=Actc1
Synonyms=Actc
Encoded on
Name=Actc1; Synonyms=Actc
Keywords
Acetylation
;
ATP-binding
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Methylation
;
Muscle protein
;
Nucleotide-binding
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X80130; CAA56429.1
; -; mRNA
EMBL
BC127451; AAI27452.1
; -; mRNA
IPI
IPI00194087; -
; .
RefSeq
NP_062056.1; NM_019183.1
; .
UniGene
Rn.3114; -
; .
ProteinModelPortal
P68035; -
; .
SMR
P68035; 6-377
; .
STRING
P68035; -
; .
PhosphoSite
P68035; -
; .
Rat-heart-2DPAGE
P68035; -
; .
PRIDE
P68035; -
; .
Ensembl
ENSRNOT00000011773; ENSRNOP00000011773
; ENSRNOG00000008536; .
GeneID
29275; -
; .
KEGG
rno:29275; -
; .
UCSC
NM_019183; rat
; .
CTD
70; -
; .
RGD
2026; Actc1
; .
eggNOG
maNOG16686; -
; .
GeneTree
ENSGT00590000082732; -
; .
HOVERGEN
HBG003771; -
; .
InParanoid
P68035; -
; .
OMA
GERFRCP; -
; .
PhylomeDB
P68035; -
; .
NextBio
608635; -
; .
ArrayExpress
P68035; -
; .
Genevestigator
P68035; -
; .
GermOnline
ENSRNOG00000008536; Rattus norvegicus
; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0005524; F:ATP binding
; IEA:UniProtKB-KW; .
GO
GO:0060048; P:cardiac muscle contraction
; IDA:RGD; .
GO
GO:0042493; P:response to drug
; IEP:RGD; .
GO
GO:0045471; P:response to ethanol
; IEP:RGD; .
InterPro
IPR004000; Actin-like
; .
InterPro
IPR020902; Actin/actin-like_CS
; .
InterPro
IPR004001; Actin_CS
; .
KO
K12314; -
; .
PANTHER
PTHR11937; Actin_like
; 1; .
Pfam
PF00022; Actin
; 1; .
PRINTS
PR00190; ACTIN
; .
SMART
SM00268; ACTIN
; 1; .
PROSITE
PS00406; ACTINS_1
; 1; .
PROSITE
PS00432; ACTINS_2
; 1; .
PROSITE
PS01132; ACTINS_ACT_LIKE
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server