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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0022]' for entry
matching:
ACY1A_RAT
World-2DPAGE Repository
(0022):
ACY1A_RAT
ACY1A_RAT
General information about the entry
View entry in simple text format
Entry name
ACY1A_RAT
Primary accession number
Q6AYS7
integrated into World-2DPAGE Repository (0022) on
May 7, 2010 (release 1)
2D Annotations were last modified on
June 22, 2011 (version 2)
General Annotations were last modified on
November 24, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Aminoacylase-1A; Short=ACY-1A; EC=3.5.1.14; AltName: Full=ACY IA; AltName: Full=N-acyl-L-amino-acid amidohydrolase;.
Gene name
Name=Acy1a
Synonyms=Acy1
Annotated species
Rattus [TaxID:
10114
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.201000593
;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein
HCR_LCR_HEART
{HCR LCR Cardiac Map}
Rattus
Tissue: Heart
map experimental info
HCR_LCR_HEART
MAP LOCATIONS:
SPOT 307
:
pI=6.03; Mw=46060
[identification data]
IDENTIFICATION:
SPOT 307: SeqCov=28.9%. Peptides MS=10/20. Mascot PMF Score=91 [
1
].
MAPPING (identification):
SPOT
307
:
Peptide mass fingerprinting
[
1
].
Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-Prot
Q6AYS7; ACY1A_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
ACY1A_RAT
Primary accession number
Q6AYS7
Secondary accession number(s)
Q6PTT1
Sequence was last modified on
September 13, 2004 (version 1)
Annotations were last modified on
November 16, 2011 (version 59)
Name and origin of the protein
Description
RecName: Full=Aminoacylase-1A; Short=ACY-1A; EC=3.5.1.14; AltName: Full=ACY IA; AltName: Full=N-acyl-L-amino-acid amidohydrolase;
Gene name
Name=Acy1a
Synonyms=Acy1
Encoded on
Name=Acy1a; Synonyms=Acy1
Keywords
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Hydrolase
;
Metal-binding
;
Reference proteome
;
Zinc
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AY580164; AAS90690.1
; -; mRNA
EMBL
BC078930; AAH78930.1
; -; mRNA
IPI
IPI00464791; -
; .
RefSeq
NP_001005383.1; NM_001005383.1
; .
UniGene
Rn.3679; -
; .
HSSP
Q03154; 1Q7L
; .
ProteinModelPortal
Q6AYS7; -
; .
SMR
Q6AYS7; 7-198
; 321-408; .
STRING
Q6AYS7; -
; .
PRIDE
Q6AYS7; -
; .
Ensembl
ENSRNOT00000015851; ENSRNOP00000015852
; ENSRNOG00000011189; .
GeneID
300981; -
; .
KEGG
rno:300981; -
; .
CTD
95; -
; .
RGD
2030; Acy1
; .
eggNOG
roNOG07630; -
; .
HOVERGEN
HBG000982; -
; .
InParanoid
Q6AYS7; -
; .
OMA
DYLRIRT; -
; .
OrthoDB
EOG46143V; -
; .
PhylomeDB
Q6AYS7; -
; .
BRENDA
3.5.1.14; 5301
; .
NextBio
647830; -
; .
ArrayExpress
Q6AYS7; -
; .
Genevestigator
Q6AYS7; -
; .
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0004046; F:aminoacylase activity
; IEA:EC; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0008237; F:metallopeptidase activity
; IEA:InterPro; .
GO
GO:0006520; P:cellular amino acid metabolic process
; IEA:InterPro; .
GO
GO:0006508; P:proteolysis
; IEA:InterPro; .
InterPro
IPR001261; ArgE/DapE_CS
; .
InterPro
IPR010159; N-acyl_aa_amidohydrolase
; .
InterPro
IPR002933; Peptidase_M20
; .
InterPro
IPR011650; Peptidase_M20_dimer
; .
KO
K14677; -
; .
Pfam
PF07687; M20_dimer
; 1; .
Pfam
PF01546; Peptidase_M20
; 1; .
PIRSF
PIRSF036696; ACY-1
; 1; .
SUPFAM
SSF55031; Peptidase_M20_dimer
; 1; .
TIGRFAMs
TIGR01880; Ac-peptdase-euk
; 1; .
PROSITE
PS00758; ARGE_DAPE_CPG2_1
; 1; .
PROSITE
PS00759; ARGE_DAPE_CPG2_2
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
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, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
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