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Searching in 'World-2DPAGE Repository [0027]' for entry matching: ALBU_MOUSE




World-2DPAGE Repository (0027):  ALBU_MOUSE


ALBU_MOUSE


General information about the entry
View entry in simple text format
Entry nameALBU_MOUSE
Primary accession numberP07724
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serum albumin; Flags: Precursor;.
Gene nameName=Alb
Synonyms=Alb-1, Alb1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/prca.201000103;
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GH_4-7 {glomerular protein lysates of a GH-tg animal}
Mus musculus (Mouse)
GH_4-7
  map experimental info
 
GH_4-7

MAP LOCATIONS:
pI=5.70; Mw=71000  [identification data]
pI=5.60; Mw=71000  [identification data]
pI=5.70; Mw=38000  [identification data]

EXPRESSION:
SPOT 6: Avg ratio GH-tg vs. control=2.06 (p-value=1.2x10-6) [1];
SPOT 7: Avg ratio GH-tg vs. control=1.99 (p-value=0.00018) [1];
SPOT 14: Avg ratio GH-tg vs. control=4.17 (p-value=0.0011) [1].

IDENTIFICATION: SPOT 6: SeqCov=50%. Mascot protein score=601 [1]
SPOT 7: SeqCov=42%. Mascot protein score=384 [1]; SPOT 14: SeqCov=25%. Mascot protein score=230 [1].
MAPPING (identification):
SPOT 6: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 7: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 14: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
Cross-references
REPRODUCTION-2DPAGEIPI00131695; IPI00131695.
REPRODUCTION-2DPAGEP07724; P07724.
SWISS-2DPAGEP07724; ALBU_MOUSE.
UCD-2DPAGEP07724; ALBU_MOUSE.
UniProtKB/Swiss-ProtP07724; ALBU_MOUSE.
World-2DPAGE RepositoryP07724; ALBU_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameALBU_MOUSE
Primary accession numberP07724
Secondary accession number(s) Q3TV03 Q61802 Q8C7C7 Q8C7H3 Q8CG74
Sequence was last modified on July 15, 1999 (version 3)
Annotations were last modified on November 16, 2011 (version 126)
Name and origin of the protein
DescriptionRecName: Full=Serum albumin; Flags: Precursor;
Gene nameName=Alb
Synonyms=Alb-1, Alb1
Encoded onName=Alb; Synonyms=Alb-1, Alb1
KeywordsCleavage on pair of basic residues; Complete proteome; Copper; Direct protein sequencing; Disulfide bond; Lipid-binding; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Secreted; Signal; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAJ011413; CAA09617.1; -; mRNA
EMBLAJ277794; CAC81903.1; -; Genomic_DNA
EMBLAK010025; BAB26650.1; -; mRNA
EMBLAK050248; BAC34145.1; -; mRNA
EMBLAK050644; BAC34360.1; -; mRNA
EMBLAK160487; BAE35818.1; -; mRNA
EMBLBC024643; AAH24643.1; -; mRNA
EMBLBC049971; AAH49971.1; -; mRNA
EMBLM16111; AAA37190.1; -; mRNA
EMBLX13060; CAA31458.1; -; Genomic_DNA
IPIIPI00131695; -; .
PIRA05139; A05139; .
RefSeqNP_033784.2; NM_009654.3; .
UniGeneMm.16773; -; .
ProteinModelPortalP07724; -; .
SMRP07724; 29-585; .
IntActP07724; 4; .
STRINGP07724; -; .
Allergome755; Mus m MSA; .
PhosphoSiteP07724; -; .
SWISS-2DPAGEP07724; -; .
REPRODUCTION-2DPAGEIPI00131695; -; .
REPRODUCTION-2DPAGEP07724; -; .
REPRODUCTION-2DPAGEQ8CG74; -; .
UCD-2DPAGEP07724; -; .
PRIDEP07724; -; .
EnsemblENSMUST00000031314; ENSMUSP00000031314; ENSMUSG00000029368; .
GeneID11657; -; .
KEGGmmu:11657; -; .
CTD213; -; .
MGIMGI:87991; Alb; .
eggNOGroNOG13173; -; .
HOGENOMHBG283181; -; .
HOVERGENHBG004207; -; .
InParanoidP07724; -; .
OMANRLCVLH; -; .
OrthoDBEOG4Z0B55; -; .
PhylomeDBP07724; -; .
NextBio279275; -; .
ArrayExpressP07724; -; .
BgeeP07724; -; .
CleanExMM_ALB; -; .
GenevestigatorP07724; -; .
GermOnlineENSMUSG00000029368; Mus musculus; .
GOGO:0005737; C:cytoplasm; IDA:MGI; .
GOGO:0005615; C:extracellular space; IDA:MGI; .
GOGO:0043234; C:protein complex; ISS:UniProtKB; .
GOGO:0003677; F:DNA binding; ISS:UniProtKB; .
GOGO:0008144; F:drug binding; ISS:UniProtKB; .
GOGO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB; .
GOGO:0015643; F:toxin binding; ISS:UniProtKB; .
GOGO:0009267; P:cellular response to starvation; ISS:UniProtKB; .
GOGO:0019836; P:hemolysis by symbiont of host erythrocytes; ISS:UniProtKB; .
GOGO:0051659; P:maintenance of mitochondrion location; ISS:UniProtKB; .
GOGO:0043066; P:negative regulation of apoptosis; ISS:UniProtKB; .
GOGO:0006810; P:transport; IEA:InterPro; .
InterProIPR000264; Serum_albumin; .
InterProIPR020858; Serum_albumin-like; .
InterProIPR020857; Serum_albumin_CS; .
InterProIPR014760; Serum_albumin_N; .
InterProIPR021177; Serum_albumin_subgr; .
PfamPF00273; Serum_albumin; 3; .
PIRSFPIRSF002520; Serum_albumin_subgroup; 1; .
PRINTSPR00802; SERUMALBUMIN; .
SMARTSM00103; ALBUMIN; 3; .
SUPFAMSSF48552; Serum_albumin; 3; .
PROSITEPS00212; ALBUMIN_1; 3; .
PROSITEPS51438; ALBUMIN_2; 3; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server