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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0019]' for entry matching: CH60_RAT World-2DPAGE Repository (0019):  CH60_RAT CH60_RAT General information about the entry View entry in simple text format Entry name CH60_RAT Primary accession number P63039 integrated into World-2DPAGE Repository (0019) on  December 9, 2009 (release 1) 2D Annotations were last modified on May 30, 2011 (version 2) General Annotations were last modified on  January 13, 2012 (version 2) Name and origin of the protein Description RecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor;. Gene name Name=Hspd1 Synonyms=Hsp60 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1111/j.1471-4159.2010.06719.x; VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M. ''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome'' J of Neurochemistry 113(6):1577-1588 (2010) 2D PAGE maps for identified proteins How to interpret a protein HIPP_SYNAP {Rat hippocampal synaptoproteome} Rattus norvegicus (Rat) Tissue: Hippocampus   map experimental info   HIPP_SYNAP MAP LOCATIONS: SPOT 381: pI=5.91; Mw=61098   [identification data] SPOT 383: pI=5.91; Mw=61098   [identification data] SPOT 386: pI=5.91; Mw=61098   [identification data] SPOT 387: pI=5.91; Mw=61098   [identification data] SPOT 645: pI=5.91; Mw=61098   [identification data] IDENTIFICATION: SPOT 381: Peptides number=9. SeqCov=25%. MOWSE score=2.00E+13 [1] SPOT 383: Peptides number=9. SeqCov=18%. MOWSE score=2.02E+9 [1]; SPOT 386: Peptides number=12. SeqCov=18%. MOWSE score=2.27E+5 [1]; SPOT 387: Peptides number=11. SeqCov=23.2%. MOWSE score=2.83E+11 [1]; SPOT 645: Peptides number=3. SeqCov=7.5%. MOWSE score=4.38E+3 [1]. MAPPING (identification): SPOT 381: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 383: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 386: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 387: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 645: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Willard Freeman, Penn State College of Medicine, USA Cross-references UniProtKB/Swiss-Prot P63039; CH60_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_12 Entry name CH60_RAT Primary accession number P63039 Secondary accession number(s) P19226 P19227 P97602 Sequence was last modified on  August 31, 2004 (version 1) Annotations were last modified on  November 16, 2011 (version 74) Name and origin of the protein Description RecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor; Gene name Name=Hspd1 Synonyms=Hsp60 Encoded on Name=Hspd1; Synonyms=Hsp60 Keywords Acetylation; ATP-binding; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X54793; CAA38564.1; -; mRNA EMBL U68562; AAC53362.1; -; Genomic_DNA EMBL BC086507; AAH86507.1; -; mRNA EMBL X53585; CAA37654.1; -; mRNA IPI IPI00339148; -; . PIR S13089; HHRT60; . RefSeq NP_071565.2; NM_022229.2; . UniGene Rn.102058; -; . ProteinModelPortal P63039; -; . SMR P63039; 27-554; . IntAct P63039; 2; . MINT MINT-1860257; -; . STRING P63039; -; . PhosphoSite P63039; -; . World-2DPAGE 0004:P63039; -; . PRIDE P63039; -; . Ensembl ENSRNOT00000019912; ENSRNOP00000019912; ENSRNOG00000014525; . GeneID 63868; -; . KEGG rno:63868; -; . UCSC NM_022229; rat; . CTD 3329; -; . RGD 621314; Hspd1; . eggNOG roNOG14286; -; . GeneTree ENSGT00390000005727; -; . HOVERGEN HBG001982; -; . InParanoid P63039; -; . OrthoDB EOG4PK27J; -; . PhylomeDB P63039; -; . NextBio 612488; -; . Genevestigator P63039; -; . GermOnline ENSRNOG00000014525; Rattus norvegicus; . GO GO:0009986; C:cell surface; IDA:RGD; . GO GO:0005829; C:cytosol; IDA:RGD; . GO GO:0005794; C:Golgi apparatus; IDA:RGD; . GO GO:0045121; C:membrane raft; IDA:RGD; . GO GO:0030061; C:mitochondrial crista; IDA:RGD; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0005791; C:rough endoplasmic reticulum; IDA:RGD; . GO GO:0042588; C:zymogen granule; IDA:RGD; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0043559; F:insulin binding; IPI:RGD; . GO GO:0051787; F:misfolded protein binding; IPI:RGD; . GO GO:0002020; F:protease binding; IPI:RGD; . GO GO:0046982; F:protein heterodimerization activity; IPI:RGD; . GO GO:0006916; P:anti-apoptosis; IMP:RGD; . GO GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:RGD; . GO GO:0002236; P:detection of misfolded protein; IDA:RGD; . GO GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD; . GO GO:0050729; P:positive regulation of inflammatory response; IDA:RGD; . GO GO:0042026; P:protein refolding; IEA:InterPro; . GO GO:0033198; P:response to ATP; IEP:RGD; . GO GO:0042220; P:response to cocaine; IEP:RGD; . GO GO:0042493; P:response to drug; IEP:RGD; . GO GO:0043627; P:response to estrogen stimulus; IEP:RGD; . GO GO:0009408; P:response to heat; IEP:RGD; . GO GO:0042542; P:response to hydrogen peroxide; IEP:RGD; . GO GO:0001666; P:response to hypoxia; IEP:RGD; . GO GO:0032496; P:response to lipopolysaccharide; IEP:RGD; . InterPro IPR018370; Chaperonin_Cpn60_CS; . InterPro IPR001844; Chaprnin_Cpn60; . InterPro IPR002423; Cpn60/TCP-1; . KO K04077; -; . PANTHER PTHR11353; Cpn60/TCP-1; 1; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00298; CHAPERONIN60; . SUPFAM SSF48592; GroEL-ATPase; 1; . TIGRFAMs TIGR02348; GroEL; 1; . PROSITE PS00296; CHAPERONINS_CPN60; 1; . World-2DPAGE Repository (search AC)