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Searching in 'World-2DPAGE Repository [0022]' for entry matching: CPT2_RAT




World-2DPAGE Repository (0022):  CPT2_RAT


CPT2_RAT


General information about the entry
View entry in simple text format
Entry nameCPT2_RAT
Primary accession numberP18886
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Carnitine O-palmitoyltransferase 2, mitochondrial; EC=2.3.1.21; AltName: Full=Carnitine palmitoyltransferase II; Short=CPT II; Flags: Precursor;.
Gene nameName=Cpt2
Synonyms=Cpt-2
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=6.89; Mw=74634  [identification data]
pI=6.89; Mw=74634  [identification data]
pI=6.89; Mw=74634  [identification data]
pI=6.89; Mw=74634  [identification data]

IDENTIFICATION: SPOT 253: SeqCov=16.6%. Peptides MS=8/20. Mascot PMF Score=54 [1]
SPOT 325: SeqCov=30.4%. Peptides MS=17/20. Mascot PMF Score=161 [1]; SPOT 376: SeqCov=32.1%. Peptides MS=16/20. Mascot PMF Score=156 [1]; SPOT 553: SeqCov=22.8%. Peptides MS=13/20. Mascot PMF Score=94 [1].
PEPTIDE EVIDENCE: SPOT 253: 383-FFNEVFR-389 (38) / 64-YLNAQKPLLDDSQFR-78 (55) / 275-YILSDSSPVPEFPVAYLTSENR-296 (41) [1]
SPOT 553: 383-FFNEVFR-389 (47) / 275-YILSDSSPVPEFPVAYLTSENR-296 (145) / 355-SFNLIVAEDGTAAVHFEHSWGDGVAVLR-382 (83) [1].
MAPPING (identification):
SPOT 253: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 325: Peptide mass fingerprinting [1];
SPOT 376: Peptide mass fingerprinting [1];
SPOT 553: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP18886; CPT2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameCPT2_RAT
Primary accession numberP18886
Secondary accession number(s) P97781
Sequence was last modified on November 1, 1990 (version 1)
Annotations were last modified on November 16, 2011 (version 102)
Name and origin of the protein
DescriptionRecName: Full=Carnitine O-palmitoyltransferase 2, mitochondrial; EC=2.3.1.21; AltName: Full=Carnitine palmitoyltransferase II; Short=CPT II; Flags: Precursor;
Gene nameName=Cpt2
Synonyms=Cpt-2
Encoded onName=Cpt2; Synonyms=Cpt-2
Keywords3D-structure; Acetylation; Acyltransferase; Complete proteome; Direct protein sequencing; Fatty acid metabolism; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transferase; Transit peptide; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLJ05470; AAB02339.1; -; mRNA
EMBLU88295; AAB48047.1; -; mRNA
IPIIPI00195593; -; .
PIRA35447; A35447; .
RefSeqNP_037062.1; NM_012930.1; .
UniGeneRn.11389; -; .
PDB2DEB; X-ray; 1.60 A; A/B=27-658
PDB2FW3; X-ray; 2.50 A; A=27-658
PDB2FYO; X-ray; 2.00 A; A=27-658
PDB2H4T; X-ray; 1.90 A; A/B=32-656
PDB2RCU; X-ray; 1.78 A; A/B=27-658
PDBsum2DEB; -; .
PDBsum2FW3; -; .
PDBsum2FYO; -; .
PDBsum2H4T; -; .
PDBsum2RCU; -; .
ProteinModelPortalP18886; -; .
SMRP18886; 32-658; .
STRINGP18886; -; .
PRIDEP18886; -; .
GeneID25413; -; .
KEGGrno:25413; -; .
UCSCNM_012930; rat; .
CTD1376; -; .
RGD2398; Cpt2; .
eggNOGroNOG04743; -; .
GeneTreeENSGT00550000074786; -; .
HOVERGENHBG098001; -; .
InParanoidP18886; -; .
OrthoDBEOG4WM4TB; -; .
PhylomeDBP18886; -; .
BioCycMetaCyc:MONOMER-14441; -; .
NextBio606547; -; .
ArrayExpressP18886; -; .
GenevestigatorP18886; -; .
GermOnlineENSRNOG00000012443; Rattus norvegicus; .
GOGO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell; .
GOGO:0004095; F:carnitine O-palmitoyltransferase activity; IDA:RGD; .
GOGO:0006635; P:fatty acid beta-oxidation; TAS:RGD; .
GOGO:0015909; P:long-chain fatty acid transport; TAS:RGD; .
InterProIPR000542; Carn_acyl_trans; .
KOK08766; -; .
PANTHERPTHR22589; Carn_acyl_trans; 1; .
PfamPF00755; Carn_acyltransf; 1; .
PROSITEPS00439; ACYLTRANSF_C_1; 1; .
PROSITEPS00440; ACYLTRANSF_C_2; 1; .



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