Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: CRYAB_RAT World-2DPAGE Repository (0022):  CRYAB_RAT CRYAB_RAT General information about the entry View entry in simple text format Entry name CRYAB_RAT Primary accession number P23928 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Alpha-crystallin B chain; AltName: Full=Alpha(B)-crystallin;. Gene name Name=Cryab Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 20: pI=6.76; Mw=20076   [identification data] SPOT 640: pI=6.76; Mw=20076   [identification data] SPOT 717: pI=6.76; Mw=20076   [identification data] IDENTIFICATION: SPOT 20: SeqCov=26.9%. Peptides MS=6/20. Mascot PMF Score=44 [1] SPOT 640: SeqCov=47.4%. Peptides MS=9/20. Mascot PMF Score=78 [1]; SPOT 717: SeqCov=47.4%. Peptides MS=9/20. Mascot PMF Score=91 [1]. PEPTIDE EVIDENCE: SPOT 20: 158-TIPITR-163 (12) / 108-QDEHGFISR-116 (54) / 12-RPFFPFHSPSR-22 (42) [1] SPOT 640: 158-TIPITR-163 (15) / 108-QDEHGFISR-116 (60) / 12-RPFFPFHSPSR-22 (81) [1]; SPOT 717: 158-TIPITR-163 (31) / 108-QDEHGFISR-116 (60) / 12-RPFFPFHSPSR-22 (80) [1]. MAPPING (identification): SPOT 20: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 640: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 717: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P23928; CRYAB_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name CRYAB_RAT Primary accession number P23928 Secondary accession number(s) Q6LDR2 Sequence was last modified on  March 1, 1992 (version 1) Annotations were last modified on  November 16, 2011 (version 103) Name and origin of the protein Description RecName: Full=Alpha-crystallin B chain; AltName: Full=Alpha(B)-crystallin; Gene name Name=Cryab Encoded on Name=Cryab Keywords Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Eye lens protein; Glycoprotein; Methylation; Nucleus; Oxidation; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL S74229; AAB20759.1; -; mRNA EMBL S77138; AAP31995.1; -; mRNA EMBL M55534; AAA40977.1; -; mRNA EMBL X60352; CAA42911.1; ALT_INIT; mRNA EMBL X60351; CAA42910.1; -; mRNA EMBL S77142; -; NOT_ANNOTATED_CDS; mRNA EMBL U04320; AAA03655.1; -; Unassigned_DNA EMBL M24092; AAA40978.1; -; mRNA IPI IPI00215465; -; . PIR A23681; A23681; . RefSeq NP_037067.1; NM_012935.3; . UniGene Rn.98208; -; . ProteinModelPortal P23928; -; . IntAct P23928; 1; . MINT MINT-6801317; -; . STRING P23928; -; . PhosphoSite P23928; -; . Rat-heart-2DPAGE P23928; -; . PRIDE P23928; -; . Ensembl ENSRNOT00000059127; ENSRNOP00000055901; ENSRNOG00000010524; . GeneID 25420; -; . KEGG rno:25420; -; . UCSC M55534; rat; . CTD 1410; -; . RGD 2414; Cryab; . eggNOG roNOG11002; -; . GeneTree ENSGT00550000074302; -; . HOVERGEN HBG054766; -; . OrthoDB EOG4G1MHK; -; . PhylomeDB P23928; -; . NextBio 606579; -; . ArrayExpress P23928; -; . Genevestigator P23928; -; . GermOnline ENSRNOG00000010524; Rattus norvegicus; . GO GO:0032432; C:actin filament bundle; IDA:RGD; . GO GO:0009986; C:cell surface; IDA:RGD; . GO GO:0005794; C:Golgi apparatus; IDA:RGD; . GO GO:0015630; C:microtubule cytoskeleton; IDA:RGD; . GO GO:0005634; C:nucleus; ISS:UniProtKB; . GO GO:0008017; F:microtubule binding; IDA:RGD; . GO GO:0042803; F:protein homodimerization activity; ISS:UniProtKB; . GO GO:0005212; F:structural constituent of eye lens; TAS:RGD; . GO GO:0007568; P:aging; IEP:RGD; . GO GO:0006006; P:glucose metabolic process; IMP:RGD; . GO GO:0031109; P:microtubule polymerization or depolymerization; IMP:RGD; . GO GO:0030308; P:negative regulation of cell growth; IDA:RGD; . GO GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:RGD; . GO GO:0006457; P:protein folding; IDA:RGD; . GO GO:0032355; P:response to estradiol stimulus; IEP:RGD; . GO GO:0042542; P:response to hydrogen peroxide; IEP:RGD; . GO GO:0051403; P:stress-activated MAPK cascade; IMP:RGD; . InterPro IPR001436; Alpha-crystallin/HSP; . InterPro IPR012273; Alpha-crystallin_B; . InterPro IPR003090; Alpha-crystallin_N; . InterPro IPR002068; Hsp20; . InterPro IPR008978; HSP20-like_chaperone; . KO K09542; -; . PANTHER PTHR11527:SF37; A-crystallin_B; 1; . Pfam PF00525; Crystallin; 1; . Pfam PF00011; HSP20; 1; . PIRSF PIRSF036514; Sm_HSP_B1; 1; . PRINTS PR00299; ACRYSTALLIN; . SUPFAM SSF49764; HSP20_chap; 1; . PROSITE PS01031; HSP20; 1; . World-2DPAGE Repository (search AC)