resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository no longer accepts submissions.

World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]


use 'Ctrl' to select several

Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'World-2DPAGE Repository [0022]' for entry matching: DHSB_RAT

World-2DPAGE Repository (0022):  DHSB_RAT


General information about the entry
View entry in simple text format
Entry nameDHSB_RAT
Primary accession numberP21913
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; EC=; AltName: Full=Iron-sulfur subunit of complex II; Short=Ip; Flags: Precursor;.
Gene nameName=Sdhb
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

Tissue: Heart
  map experimental info

pI=8.96; Mw=32607  [identification data]

IDENTIFICATION: SPOT 182: SeqCov=18.1%. Peptides MS=5/20. Mascot PMF Score=32 [1].
PEPTIDE EVIDENCE: SPOT 182: 236-LQDPFSLYR-244 (23) / 140-DLVPDLSNFYAQYK-153 (79) [1].
MAPPING (identification):
SPOT 182: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
UniProtKB/Swiss-ProtP21913; DHSB_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameDHSB_RAT
Primary accession numberP21913
Secondary accession number(s) B0BMZ2 Q0QEZ3
Sequence was last modified on September 2, 2008 (version 2)
Annotations were last modified on November 16, 2011 (version 107)
Name and origin of the protein
DescriptionRecName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; EC=; AltName: Full=Iron-sulfur subunit of complex II; Short=Ip; Flags: Precursor;
Gene nameName=Sdhb
Encoded onName=Sdhb; Synonyms=Sdh1
Keywords2Fe-2S; 3Fe-4S; 4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Reference proteome; Transit peptide; Transport; Tricarboxylic acid cycle.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLCH473968; EDL80954.1; -; Genomic_DNA
EMBLBC158620; AAI58621.1; -; mRNA
EMBLDQ403001; ABD77134.1; -; mRNA
IPIIPI00785564; -; .
PIRB32394; B32394; .
RefSeqNP_001094009.1; NM_001100539.1; .
UniGeneRn.3902; -; .
ProteinModelPortalP21913; -; .
SMRP21913; 39-277; .
STRINGP21913; -; .
PhosphoSiteP21913; -; .
PRIDEP21913; -; .
EnsemblENSRNOT00000010593; ENSRNOP00000010593; ENSRNOG00000007967; .
GeneID298596; -; .
KEGGrno:298596; -; .
CTD6390; -; .
RGD1308598; Sdhb; .
eggNOGroNOG06326; -; .
GeneTreeENSGT00390000013558; -; .
HOVERGENHBG005483; -; .
InParanoidP21913; -; .
OrthoDBEOG4T4CW4; -; .
PhylomeDBP21913; -; .
ArrayExpressP21913; -; .
GenevestigatorP21913; -; .
GermOnlineENSRNOG00000007967; Rattus norvegicus; .
GOGO:0005749; C:mitochondrial respiratory chain complex II; ISS:UniProtKB; .
GOGO:0051537; F:2 iron; 2 sulfur cluster binding; ISS:UniProtKB
GOGO:0051538; F:3 iron; 4 sulfur cluster binding; ISS:UniProtKB
GOGO:0051539; F:4 iron; 4 sulfur cluster binding; ISS:UniProtKB
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IMP:RGD; .
GOGO:0048039; F:ubiquinone binding; ISS:UniProtKB; .
GOGO:0022904; P:respiratory electron transport chain; IMP:RGD; .
GOGO:0006105; P:succinate metabolic process; IMP:RGD; .
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
GOGO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW; .
InterProIPR006058; 2Fe2S_fd_BS; .
InterProIPR017896; 4Fe4S_Fe-S-bd; .
InterProIPR017900; 4Fe4S_Fe_S_CS; .
InterProIPR012675; Beta-grasp_ferredoxin-type; .
InterProIPR001041; Ferredoxin; .
InterProIPR012285; Fum_reductase_C; .
InterProIPR009051; Helical_ferredxn; .
InterProIPR004489; Succ_DH/fum_Rdtase_Fe-S; .
Gene3DG3DSA:; Ferredoxin_fold; 1; .
Gene3DG3DSA:1.10.1060.10; Fum_reductase_C; 1; .
KOK00235; -; .
SUPFAMSSF54292; Ferredoxin; 1; .
SUPFAMSSF46548; Helical_ferredxn; 1; .
TIGRFAMsTIGR00384; DhsB; 1; .
PROSITEPS00197; 2FE2S_FER_1; 1; .
PROSITEPS51085; 2FE2S_FER_2; 1; .
PROSITEPS00198; 4FE4S_FER_1; 1; .
PROSITEPS51379; 4FE4S_FER_2; 1; .

World-2DPAGE Repository image

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server