World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 174:

pI=5.91; Mw=81000

[identification data]

MAPPING (identification):

SPOT 174: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P31977; EZRI_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	EZRI_RAT
Primary accession number	P31977
Secondary accession number(s)	Q5WQV4 Q66H97 Q8VHK3
Sequence was last modified on	January 23, 2007 (version 3)
Annotations were last modified on	December 14, 2011 (version 100)
Name and origin of the protein
Description	RecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81;
Gene name	Name=Ezr Synonyms=Vil2
Encoded on	Name=Ezr; Synonyms=Vil2
Keywords	Acetylation; Cell membrane; Cell projection; Cell shape; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	AY428869; AAR91694.1; -; mRNA
EMBL	BC081958; AAH81958.1; -; mRNA
EMBL	AF450298; AAL47844.1; -; mRNA
EMBL	X67788; CAA48004.1; -; mRNA
IPI	IPI00470254; -; .
PIR	S58759; S58759; .
RefSeq	NP_062230.1; NM_019357.1; .
UniGene	Rn.773; -; .
ProteinModelPortal	P31977; -; .
SMR	P31977; 1-385; 500-586; .
IntAct	P31977; 1; .
STRING	P31977; -; .
PhosphoSite	P31977; -; .
World-2DPAGE	0004:P31977; -; .
PRIDE	P31977; -; .
Ensembl	ENSRNOT00000046746; ENSRNOP00000046593; ENSRNOG00000018524; .
GeneID	54319; -; .
KEGG	rno:54319; -; .
UCSC	AY428869; rat; .
CTD	7430; -; .
RGD	621161; Ezr; .
eggNOG	roNOG13879; -; .
GeneTree	ENSGT00600000084066; -; .
HOVERGEN	HBG002185; -; .
InParanoid	P31977; -; .
OrthoDB	EOG4C5CJJ; -; .
Reactome	REACT_112697; Developmental Biology; .
NextBio	611002; -; .
ArrayExpress	P31977; -; .
Genevestigator	P31977; -; .
GermOnline	ENSRNOG00000018524; Rattus norvegicus; .
GO	GO:0005884; C:actin filament; ISS:UniProtKB; .
GO	GO:0016324; C:apical plasma membrane; IDA:UniProtKB; .
GO	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell; .
GO	GO:0005829; C:cytosol; TAS:Reactome; .
GO	GO:0019898; C:extrinsic to membrane; ISS:UniProtKB; .
GO	GO:0031528; C:microvillus membrane; IDA:UniProtKB; .
GO	GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; .
GO	GO:0051015; F:actin filament binding; ISS:UniProtKB; .
GO	GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL; .
GO	GO:0005198; F:structural molecule activity; TAS:RGD; .
GO	GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB; .
GO	GO:0030855; P:epithelial cell differentiation; IEP:RGD; .
GO	GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW; .
InterPro	IPR019749; Band_41_domain; .
InterPro	IPR019750; Band_41_fam; .
InterPro	IPR011174; ERM; .
InterPro	IPR011259; ERM_C; .
InterPro	IPR000798; Ez/rad/moesin; .
InterPro	IPR014352; FERM/acyl-CoA-bd_prot_3-hlx; .
InterPro	IPR019748; FERM_central; .
InterPro	IPR019747; FERM_CS; .
InterPro	IPR000299; FERM_domain; .
InterPro	IPR018979; FERM_N; .
InterPro	IPR018980; FERM_PH-like_C; .
InterPro	IPR008954; Moesin; .
InterPro	IPR011993; PH_type; .
Gene3D	G3DSA:1.20.80.10; ACBP; 1; .
Gene3D	G3DSA:2.30.29.30; PH_type; 1; .
KO	K08007; -; .
Pfam	PF00769; ERM; 1; .
Pfam	PF09380; FERM_C; 1; .
Pfam	PF00373; FERM_M; 1; .
Pfam	PF09379; FERM_N; 1; .
PIRSF	PIRSF002305; ERM; 1; .
PRINTS	PR00935; BAND41; .
PRINTS	PR00661; ERMFAMILY; .
SMART	SM00295; B41; 1; .
SUPFAM	SSF47031; FERM_3-hlx; 1; .
SUPFAM	SSF48678; Moesin; 1; .
PROSITE	PS00660; FERM_1; 1; .
PROSITE	PS00661; FERM_2; 1; .
PROSITE	PS50057; FERM_3; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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