Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: EZRI_RAT World-2DPAGE Repository (0022):  EZRI_RAT EZRI_RAT General information about the entry View entry in simple text format Entry name EZRI_RAT Primary accession number P31977 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81;. Gene name Name=Ezr Synonyms=Vil2 Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 416: pI=5.83; Mw=69462   [identification data] IDENTIFICATION: SPOT 416: SeqCov=17.6%. Peptides MS=12/20. Mascot PMF Score=62 [1]. PEPTIDE EVIDENCE: SPOT 416: 238-IGFPWSEIR-246 (62) / 172-IQVWHAEHR-180 (17) / 264-APDFVFYAPR-273 (50) [1]. MAPPING (identification): SPOT 416: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P31977; EZRI_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name EZRI_RAT Primary accession number P31977 Secondary accession number(s) Q5WQV4 Q66H97 Q8VHK3 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 99) Name and origin of the protein Description RecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81; Gene name Name=Ezr Synonyms=Vil2 Encoded on Name=Ezr; Synonyms=Vil2 Keywords Acetylation; Cell membrane; Cell projection; Cell shape; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AY428869; AAR91694.1; -; mRNA EMBL BC081958; AAH81958.1; -; mRNA EMBL AF450298; AAL47844.1; -; mRNA EMBL X67788; CAA48004.1; -; mRNA IPI IPI00470254; -; . PIR S58759; S58759; . RefSeq NP_062230.1; NM_019357.1; . UniGene Rn.773; -; . ProteinModelPortal P31977; -; . SMR P31977; 1-385; 500-586; . IntAct P31977; 1; . STRING P31977; -; . PhosphoSite P31977; -; . World-2DPAGE 0004:P31977; -; . PRIDE P31977; -; . Ensembl ENSRNOT00000046746; ENSRNOP00000046593; ENSRNOG00000018524; . GeneID 54319; -; . KEGG rno:54319; -; . UCSC AY428869; rat; . CTD 7430; -; . RGD 621161; Ezr; . eggNOG roNOG13879; -; . GeneTree ENSGT00600000084066; -; . HOVERGEN HBG002185; -; . InParanoid P31977; -; . OrthoDB EOG4C5CJJ; -; . Reactome REACT_112697; Developmental Biology; . NextBio 611002; -; . ArrayExpress P31977; -; . Genevestigator P31977; -; . GermOnline ENSRNOG00000018524; Rattus norvegicus; . GO GO:0005884; C:actin filament; ISS:UniProtKB; . GO GO:0016324; C:apical plasma membrane; IDA:UniProtKB; . GO GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0019898; C:extrinsic to membrane; ISS:UniProtKB; . GO GO:0031528; C:microvillus membrane; IDA:UniProtKB; . GO GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; . GO GO:0051015; F:actin filament binding; ISS:UniProtKB; . GO GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL; . GO GO:0005198; F:structural molecule activity; TAS:RGD; . GO GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB; . GO GO:0030855; P:epithelial cell differentiation; IEP:RGD; . GO GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW; . InterPro IPR019749; Band_41_domain; . InterPro IPR019750; Band_41_fam; . InterPro IPR011174; ERM; . InterPro IPR011259; ERM_C; . InterPro IPR000798; Ez/rad/moesin; . InterPro IPR014352; FERM/acyl-CoA-bd_prot_3-hlx; . InterPro IPR019748; FERM_central; . InterPro IPR019747; FERM_CS; . InterPro IPR000299; FERM_domain; . InterPro IPR018979; FERM_N; . InterPro IPR018980; FERM_PH-like_C; . InterPro IPR008954; Moesin; . InterPro IPR011993; PH_type; . Gene3D G3DSA:1.20.80.10; ACBP; 1; . Gene3D G3DSA:2.30.29.30; PH_type; 1; . KO K08007; -; . Pfam PF00769; ERM; 1; . Pfam PF09380; FERM_C; 1; . Pfam PF00373; FERM_M; 1; . Pfam PF09379; FERM_N; 1; . PIRSF PIRSF002305; ERM; 1; . PRINTS PR00935; BAND41; . PRINTS PR00661; ERMFAMILY; . SMART SM00295; B41; 1; . SUPFAM SSF47031; FERM_3-hlx; 1; . SUPFAM SSF48678; Moesin; 1; . PROSITE PS00660; FERM_1; 1; . PROSITE PS00661; FERM_2; 1; . PROSITE PS50057; FERM_3; 1; . World-2DPAGE Repository (search AC)