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Searching in 'World-2DPAGE Repository [0027]' for entry matching: GPX1_MOUSE




World-2DPAGE Repository (0027):  GPX1_MOUSE


GPX1_MOUSE


General information about the entry
View entry in simple text format
Entry nameGPX1_MOUSE
Primary accession numberP11352
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;.
Gene nameName=Gpx1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/prca.201000103;
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
GIPRDN_4-7
  map experimental info
 
GIPRDN_4-7

MAP LOCATIONS:
pI=5.66; Mw=22000  [identification data]

IDENTIFICATION: SPOT 34: SeqCov=23%. Mascot protein score=58 [1].
MAPPING (identification):
SPOT 34: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
Cross-references
REPRODUCTION-2DPAGEIPI00319652; IPI00319652.
REPRODUCTION-2DPAGEP11352; P11352.
SWISS-2DPAGEP11352; GPX1_MOUSE.
UniProtKB/Swiss-ProtP11352; GPX1_MOUSE.
World-2DPAGE RepositoryP11352; GPX1_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameGPX1_MOUSE
Primary accession numberP11352
Secondary accession number(s) P12079 Q544W3 Q9CR54
Sequence was last modified on February 26, 2008 (version 2)
Annotations were last modified on November 16, 2011 (version 124)
Name and origin of the protein
DescriptionRecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;
Gene nameName=Gpx1
Encoded onName=Gpx1
KeywordsAcetylation; Complete proteome; Cytoplasm; Oxidoreductase; Peroxidase; Phosphoprotein; Reference proteome; Selenocysteine.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX03920; CAA27558.1; -; Genomic_DNA
EMBLAK002245; BAC55244.1; -; mRNA
EMBLAK010999; BAC55252.1; -; mRNA
EMBLAK011019; BAC55253.1; -; mRNA
EMBLAK028171; BAC55257.1; -; mRNA
EMBLAK150548; BAE29650.1; -; mRNA
EMBLAK154833; BAE32862.1; -; mRNA
EMBLAK160388; BAE35760.1; -; mRNA
EMBLX15667; CAB43535.1; ALT_SEQ; mRNA
IPIIPI00319652; -; .
PIRA25106; OPMSE; .
PIRS05317; S05317; .
RefSeqNP_032186.2; NM_008160.6; .
UniGeneMm.1090; -; .
ProteinModelPortalP11352; -; .
SMRP11352; 13-195; .
STRINGP11352; -; .
PeroxiBase3709; MmGPx01; .
PhosphoSiteP11352; -; .
SWISS-2DPAGEP11352; -; .
REPRODUCTION-2DPAGEIPI00319652; -; .
REPRODUCTION-2DPAGEP11352; -; .
PRIDEP11352; -; .
EnsemblENSMUST00000082429; ENSMUSP00000081010; ENSMUSG00000063856; .
GeneID14775; -; .
KEGGmmu:14775; -; .
CTD2876; -; .
MGIMGI:104887; Gpx1; .
eggNOGmaNOG14464; -; .
HOGENOMHBG648990; -; .
HOVERGENHBG004333; -; .
InParanoidP11352; -; .
OMACRNDISW; -; .
OrthoDBEOG4SBF08; -; .
PhylomeDBP11352; -; .
NextBio286877; -; .
ArrayExpressP11352; -; .
BgeeP11352; -; .
CleanExMM_GPX1; -; .
GenevestigatorP11352; -; .
GermOnlineENSMUSG00000063856; Mus musculus; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0004602; F:glutathione peroxidase activity; IDA:MGI; .
GOGO:0060055; P:angiogenesis involved in wound healing; IMP:MGI; .
GOGO:0043534; P:blood vessel endothelial cell migration; IMP:MGI; .
GOGO:0001885; P:endothelial cell development; IMP:MGI; .
GOGO:0045444; P:fat cell differentiation; IMP:MGI; .
GOGO:0060047; P:heart contraction; IMP:MGI; .
GOGO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI; .
GOGO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI; .
GOGO:0051450; P:myoblast proliferation; IMP:MGI; .
GOGO:0014902; P:myotube differentiation; IMP:MGI; .
GOGO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI; .
GOGO:0018158; P:protein oxidation; IMP:MGI; .
GOGO:0043523; P:regulation of neuron apoptosis; IMP:MGI; .
GOGO:0033194; P:response to hydroperoxide; IMP:MGI; .
GOGO:0009636; P:response to toxin; IMP:MGI; .
GOGO:0009410; P:response to xenobiotic stimulus; IMP:MGI; .
GOGO:0007605; P:sensory perception of sound; IMP:MGI; .
GOGO:0048741; P:skeletal muscle fiber development; IMP:MGI; .
GOGO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI; .
GOGO:0006641; P:triglyceride metabolic process; IMP:MGI; .
GOGO:0042311; P:vasodilation; IMP:MGI; .
InterProIPR000889; Glutathione_peroxidase; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
KOK00432; -; .
PANTHERPTHR11592; Glut_peroxidase; 1; .
PfamPF00255; GSHPx; 1; .
PIRSFPIRSF000303; Glutathion_perox; 1; .
PRINTSPR01011; GLUTPROXDASE; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS00460; GLUTATHIONE_PEROXID_1; 1; .
PROSITEPS00763; GLUTATHIONE_PEROXID_2; 1; .
PROSITEPS51355; GLUTATHIONE_PEROXID_3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server