Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0027]' for entry matching: GPX1_MOUSE World-2DPAGE Repository (0027):  GPX1_MOUSE GPX1_MOUSE General information about the entry View entry in simple text format Entry name GPX1_MOUSE Primary accession number P11352 integrated into World-2DPAGE Repository (0027) on  September 30, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;. Gene name Name=Gpx1 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/prca.201000103; Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R. ''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria'' Proteomics - Clinical Applications 5(6):375-381 (2011) 2D PAGE maps for identified proteins How to interpret a protein GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal} Mus musculus (Mouse)   map experimental info   GIPRDN_4-7 MAP LOCATIONS: SPOT 34: pI=5.66; Mw=22000   [identification data] IDENTIFICATION: SPOT 34: SeqCov=23%. Mascot protein score=58 [1]. MAPPING (identification): SPOT 34: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany Cross-references REPRODUCTION-2DPAGE IPI00319652; IPI00319652. REPRODUCTION-2DPAGE P11352; P11352. SWISS-2DPAGE P11352; GPX1_MOUSE. UniProtKB/Swiss-Prot P11352; GPX1_MOUSE. World-2DPAGE Repository P11352; GPX1_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GPX1_MOUSE Primary accession number P11352 Secondary accession number(s) P12079 Q544W3 Q9CR54 Sequence was last modified on  February 26, 2008 (version 2) Annotations were last modified on  November 16, 2011 (version 124) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase; Gene name Name=Gpx1 Encoded on Name=Gpx1 Keywords Acetylation; Complete proteome; Cytoplasm; Oxidoreductase; Peroxidase; Phosphoprotein; Reference proteome; Selenocysteine. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X03920; CAA27558.1; -; Genomic_DNA EMBL AK002245; BAC55244.1; -; mRNA EMBL AK010999; BAC55252.1; -; mRNA EMBL AK011019; BAC55253.1; -; mRNA EMBL AK028171; BAC55257.1; -; mRNA EMBL AK150548; BAE29650.1; -; mRNA EMBL AK154833; BAE32862.1; -; mRNA EMBL AK160388; BAE35760.1; -; mRNA EMBL X15667; CAB43535.1; ALT_SEQ; mRNA IPI IPI00319652; -; . PIR A25106; OPMSE; . PIR S05317; S05317; . RefSeq NP_032186.2; NM_008160.6; . UniGene Mm.1090; -; . ProteinModelPortal P11352; -; . SMR P11352; 13-195; . STRING P11352; -; . PeroxiBase 3709; MmGPx01; . PhosphoSite P11352; -; . SWISS-2DPAGE P11352; -; . REPRODUCTION-2DPAGE IPI00319652; -; . REPRODUCTION-2DPAGE P11352; -; . PRIDE P11352; -; . Ensembl ENSMUST00000082429; ENSMUSP00000081010; ENSMUSG00000063856; . GeneID 14775; -; . KEGG mmu:14775; -; . CTD 2876; -; . MGI MGI:104887; Gpx1; . eggNOG maNOG14464; -; . HOGENOM HBG648990; -; . HOVERGEN HBG004333; -; . InParanoid P11352; -; . OMA CRNDISW; -; . OrthoDB EOG4SBF08; -; . PhylomeDB P11352; -; . NextBio 286877; -; . ArrayExpress P11352; -; . Bgee P11352; -; . CleanEx MM_GPX1; -; . Genevestigator P11352; -; . GermOnline ENSMUSG00000063856; Mus musculus; . GO GO:0005739; C:mitochondrion; IDA:MGI; . GO GO:0004602; F:glutathione peroxidase activity; IDA:MGI; . GO GO:0060055; P:angiogenesis involved in wound healing; IMP:MGI; . GO GO:0043534; P:blood vessel endothelial cell migration; IMP:MGI; . GO GO:0001885; P:endothelial cell development; IMP:MGI; . GO GO:0045444; P:fat cell differentiation; IMP:MGI; . GO GO:0060047; P:heart contraction; IMP:MGI; . GO GO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI; . GO GO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI; . GO GO:0051450; P:myoblast proliferation; IMP:MGI; . GO GO:0014902; P:myotube differentiation; IMP:MGI; . GO GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI; . GO GO:0018158; P:protein oxidation; IMP:MGI; . GO GO:0043523; P:regulation of neuron apoptosis; IMP:MGI; . GO GO:0033194; P:response to hydroperoxide; IMP:MGI; . GO GO:0009636; P:response to toxin; IMP:MGI; . GO GO:0009410; P:response to xenobiotic stimulus; IMP:MGI; . GO GO:0007605; P:sensory perception of sound; IMP:MGI; . GO GO:0048741; P:skeletal muscle fiber development; IMP:MGI; . GO GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI; . GO GO:0006641; P:triglyceride metabolic process; IMP:MGI; . GO GO:0042311; P:vasodilation; IMP:MGI; . InterPro IPR000889; Glutathione_peroxidase; . InterPro IPR012336; Thioredoxin-like_fold; . Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1; . KO K00432; -; . PANTHER PTHR11592; Glut_peroxidase; 1; . Pfam PF00255; GSHPx; 1; . PIRSF PIRSF000303; Glutathion_perox; 1; . PRINTS PR01011; GLUTPROXDASE; . SUPFAM SSF52833; Thiordxn-like_fd; 1; . PROSITE PS00460; GLUTATHIONE_PEROXID_1; 1; . PROSITE PS00763; GLUTATHIONE_PEROXID_2; 1; . PROSITE PS51355; GLUTATHIONE_PEROXID_3; 1; . World-2DPAGE Repository (search AC)