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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: GUAA_RAT World-2DPAGE Repository (0030):  GUAA_RAT GUAA_RAT General information about the entry View entry in simple text format Entry name GUAA_RAT Primary accession number Q4V7C6 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=GMP synthase [glutamine-hydrolyzing]; EC=6.3.5.2; AltName: Full=GMP synthetase; AltName: Full=Glutamine amidotransferase;. Gene name Name=Gmps Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 547: pI=6.43; Mw=79751   [identification data] SPOT 554: pI=6.53; Mw=79531   [identification data] IDENTIFICATION: SPOT 547: Mascot protein score=212. Number of peptides=6 [1] SPOT 554: Mascot protein score=139. Number of peptides=6 [1]. MAPPING (identification): SPOT 547: Tandem mass spectrometry [1]; SPOT 554: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot Q4V7C6; GUAA_RAT. World-2DPAGE Repository Q4V7C6; GUAA_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GUAA_RAT Primary accession number Q4V7C6 Sequence was last modified on  July 5, 2005 (version 1) Annotations were last modified on  November 16, 2011 (version 60) Name and origin of the protein Description RecName: Full=GMP synthase [glutamine-hydrolyzing]; EC=6.3.5.2; AltName: Full=GMP synthetase; AltName: Full=Glutamine amidotransferase; Gene name Name=Gmps Encoded on Name=Gmps Keywords Acetylation; ATP-binding; Complete proteome; Cytoplasm; Glutamine amidotransferase; GMP biosynthesis; Ligase; Nucleotide-binding; Phosphoprotein; Purine biosynthesis; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC098016; AAH98016.1; -; mRNA IPI IPI00372214; -; . RefSeq NP_001019925.1; NM_001024754.1; . UniGene Rn.12593; -; . HSSP O59071; 1WL8; . ProteinModelPortal Q4V7C6; -; . SMR Q4V7C6; 23-693; . STRING Q4V7C6; -; . MEROPS C26.950; -; . PRIDE Q4V7C6; -; . GeneID 295088; -; . KEGG rno:295088; -; . CTD 8833; -; . RGD 1310063; Gmps; . eggNOG roNOG15065; -; . GeneTree ENSGT00390000006591; -; . HOVERGEN HBG005929; -; . InParanoid Q4V7C6; -; . OrthoDB EOG4J6RQ9; -; . NextBio 638960; -; . ArrayExpress Q4V7C6; -; . Genevestigator Q4V7C6; -; . GO GO:0005829; C:cytosol; IDA:RGD; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0019899; F:enzyme binding; IDA:RGD; . GO GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IDA:RGD; . GO GO:0003921; F:GMP synthase activity; IDA:RGD; . GO GO:0006541; P:glutamine metabolic process; IEP:RGD; . GO GO:0042493; P:response to drug; IEP:RGD; . InterPro IPR006220; Anth_synthII; . InterPro IPR011702; GATASE; . InterPro IPR017926; GATASE_1; . InterPro IPR001674; GMP_synth_C; . InterPro IPR004739; GMP_synth_N; . InterPro IPR022310; NAD/GMP_synthase; . InterPro IPR014729; Rossmann-like_a/b/a_fold; . Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1; . KO K01951; -; . Pfam PF00117; GATase; 1; . Pfam PF00958; GMP_synt_C; 1; . Pfam PF02540; NAD_synthase; 1; . PRINTS PR00097; ANTSNTHASEII; . PRINTS PR00096; GATASE; . TIGRFAMs TIGR00888; GuaA_Nterm; 1; . PROSITE PS51273; GATASE_TYPE_1; 1; . World-2DPAGE Repository (search AC)