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Searching in 'World-2DPAGE Repository [0030]' for entry matching: HMGB1_RAT




World-2DPAGE Repository (0030):  HMGB1_RAT


HMGB1_RAT


General information about the entry
View entry in simple text format
Entry nameHMGB1_RAT
Primary accession numberP63159
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=High mobility group protein B1; AltName: Full=Amphoterin; AltName: Full=Heparin-binding protein p30; AltName: Full=High mobility group protein 1; Short=HMG-1;.
Gene nameName=Hmgb1
Synonyms=Hmg-1, Hmg1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info
 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=6.33; Mw=29742  [identification data]

IDENTIFICATION: SPOT 2079: Mascot protein score=47. Number of peptides=2 [1].
MAPPING (identification):
SPOT 2079: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtP63159; HMGB1_RAT.
World-2DPAGE RepositoryP63159; HMGB1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameHMGB1_RAT
Primary accession numberP63159
Secondary accession number(s) P07155 P27109 P27428 Q548R9
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on November 16, 2011 (version 80)
Name and origin of the protein
DescriptionRecName: Full=High mobility group protein B1; AltName: Full=Amphoterin; AltName: Full=Heparin-binding protein p30; AltName: Full=High mobility group protein 1; Short=HMG-1;
Gene nameName=Hmgb1
Synonyms=Hmg-1, Hmg1
Encoded onName=Hmgb1; Synonyms=Hmg-1, Hmg1
Keywords3D-structure; Acetylation; Chromosome; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Heparin-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM64986; AAA40729.1; -; mRNA
EMBLY00463; CAA68526.1; -; mRNA
EMBLAF275734; AAF82799.1; -; mRNA
EMBLBC061779; AAH61779.1; -; mRNA
EMBLBC081839; AAH81839.1; -; mRNA
EMBLBC088402; AAH88402.1; -; mRNA
IPIIPI00555214; -; .
PIRA41175; NSRTH1; .
RefSeqNP_037095.1; NM_012963.2; .
UniGeneRn.144565; -; .
UniGeneRn.15185; -; .
UniGeneRn.4121; -; .
PDB1AAB; NMR; -; A=2-84
PDB1CKT; X-ray; 2.50 A; A=8-77
PDB1HME; NMR; -; A=89-165
PDB1HMF; NMR; -; A=89-165
PDB2GZK; NMR; -; A=82-165
PDBsum1AAB; -; .
PDBsum1CKT; -; .
PDBsum1HME; -; .
PDBsum1HMF; -; .
PDBsum2GZK; -; .
ProteinModelPortalP63159; -; .
SMRP63159; 5-166; .
STRINGP63159; -; .
PhosphoSiteP63159; -; .
PRIDEP63159; -; .
GeneID25459; -; .
KEGGrno:25459; -; .
UCSCBC061779; rat; .
CTD3146; -; .
RGD2802; Hmgb1; .
eggNOGroNOG11154; -; .
GeneTreeENSGT00560000076717; -; .
HOVERGENHBG009000; -; .
InParanoidP63159; -; .
OrthoDBEOG4KWJV1; -; .
PhylomeDBP63159; -; .
NextBio606729; -; .
GenevestigatorP63159; -; .
GermOnlineENSRNOG00000030351; Rattus norvegicus; .
GOGO:0005694; C:chromosome; IEA:UniProtKB-SubCell; .
GOGO:0005737; C:cytoplasm; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0005634; C:nucleus; IDA:RGD; .
GOGO:0008097; F:5S rRNA binding; IDA:RGD; .
GOGO:0003681; F:bent DNA binding; IDA:MGI; .
GOGO:0000402; F:crossed form four-way junction DNA binding; IDA:MGI; .
GOGO:0005125; F:cytokine activity; IDA:UniProtKB; .
GOGO:0008301; F:DNA bending activity; IDA:RGD; .
GOGO:0003690; F:double-stranded DNA binding; IDA:RGD; .
GOGO:0051861; F:glycolipid binding; IDA:RGD; .
GOGO:0008201; F:heparin binding; IDA:RGD; .
GOGO:0000401; F:open form four-way junction DNA binding; IDA:MGI; .
GOGO:0042277; F:peptide binding; IDA:RGD; .
GOGO:0046983; F:protein dimerization activity; IDA:RGD; .
GOGO:0050786; F:RAGE receptor binding; IPI:UniProtKB; .
GOGO:0003697; F:single-stranded DNA binding; IDA:RGD; .
GOGO:0008134; F:transcription factor binding; IDA:RGD; .
GOGO:0031532; P:actin cytoskeleton reorganization; IMP:RGD; .
GOGO:0000902; P:cell morphogenesis; IMP:RGD; .
GOGO:0071347; P:cellular response to interleukin-1; IEP:RGD; .
GOGO:0006935; P:chemotaxis; IDA:RGD; .
GOGO:0007623; P:circadian rhythm; IEP:RGD; .
GOGO:0032392; P:DNA geometric change; IDA:MGI; .
GOGO:0050930; P:induction of positive chemotaxis; IDA:MGI; .
GOGO:0050831; P:male-specific defense response to bacterium; IDA:RGD; .
GOGO:0051450; P:myoblast proliferation; IMP:RGD; .
GOGO:0008156; P:negative regulation of DNA replication; IDA:RGD; .
GOGO:0031175; P:neuron projection development; IGI:UniProtKB; .
GOGO:0002053; P:positive regulation of mesenchymal cell proliferation; IDA:MGI; .
GOGO:0045931; P:positive regulation of mitotic cell cycle; IDA:MGI; .
GOGO:0033034; P:positive regulation of myeloid cell apoptosis; IDA:RGD; .
GOGO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD; .
GOGO:0010976; P:positive regulation of neuron projection development; IMP:RGD; .
GOGO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD; .
GOGO:0050727; P:regulation of inflammatory response; IDA:RGD; .
GOGO:0042493; P:response to drug; IEP:RGD; .
GOGO:0009749; P:response to glucose stimulus; IEP:RGD; .
GOGO:0009408; P:response to heat; IEP:RGD; .
GOGO:0032868; P:response to insulin stimulus; IEP:RGD; .
GOGO:0034341; P:response to interferon-gamma; IMP:RGD; .
GOGO:0032496; P:response to lipopolysaccharide; IEP:RGD; .
InterProIPR011989; ARM-like; .
InterProIPR017967; HMG_boxA_CS; .
InterProIPR000910; HMG_HMG1/HMG2; .
InterProIPR000135; HMG_HMG1/HMG2_subgr; .
InterProIPR009071; HMG_superfamily; .
Gene3DG3DSA:1.25.10.10; ARM-like; 1; .
Gene3DG3DSA:1.10.30.10; HMG-box; 2; .
KOK10802; -; .
PfamPF00505; HMG_box; 2; .
PRINTSPR00886; HIGHMOBLTY12; .
SMARTSM00398; HMG; 2; .
SUPFAMSSF47095; HMG-box; 2; .
PROSITEPS00353; HMG_BOX_1; 1; .
PROSITEPS50118; HMG_BOX_2; 2; .



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