World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 215:

pI=5.36; Mw=67000

[identification data]

MAPPING (identification):

SPOT 215: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P63018; HSP7C_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	HSP7C_RAT
Primary accession number	P63018
Secondary accession number(s)	P08109 P12225 Q4FZY7 Q62373 Q62374 Q62375
Sequence was last modified on	August 1, 1988 (version 1)
Annotations were last modified on	November 16, 2011 (version 84)
Name and origin of the protein
Description	RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8;
Gene name	Name=Hspa8 Synonyms=Hsc70, Hsc73
Encoded on	Name=Hspa8; Synonyms=Hsc70, Hsc73
Keywords	3D-structure; Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Repressor; Stress response; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	Y00054; CAA68265.1; -; Genomic_DNA
EMBL	M11942; AAA41354.1; -; mRNA
EMBL	BC061547; AAH61547.1; -; mRNA
EMBL	BC098914; AAH98914.1; -; mRNA
IPI	IPI00208205; -; .
PIR	S07197; S07197; .
RefSeq	NP_077327.1; NM_024351.2; .
UniGene	Rn.120392; -; .
UniGene	Rn.201298; -; .
PDB	1CKR; NMR; -; A=385-543
PDB	1Q2G; Model; -; C=385-543
PDB	1UD0; X-ray; 3.45 A; A/B/C/D=542-646
PDB	2V7Z; X-ray; 3.50 A; A/B=1-543
PDB	7HSC; NMR; -; A=385-543
PDBsum	1CKR; -; .
PDBsum	1Q2G; -; .
PDBsum	1UD0; -; .
PDBsum	2V7Z; -; .
PDBsum	7HSC; -; .
ProteinModelPortal	P63018; -; .
SMR	P63018; 1-621; .
IntAct	P63018; 5; .
MINT	MINT-2514077; -; .
STRING	P63018; -; .
PhosphoSite	P63018; -; .
World-2DPAGE	0004:P63018; -; .
PRIDE	P63018; -; .
GeneID	24468; -; .
KEGG	rno:24468; -; .
UCSC	BC061547; rat; .
CTD	3312; -; .
RGD	621725; Hspa8; .
eggNOG	maNOG11692; -; .
GeneTree	ENSGT00550000074467; -; .
HOVERGEN	HBG051845; -; .
OrthoDB	EOG4W6NVK; -; .
PhylomeDB	P63018; -; .
NextBio	603401; -; .
Genevestigator	P63018; -; .
GO	GO:0070062; C:extracellular vesicular exosome; IDA:RGD; .
GO	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GO	GO:0043005; C:neuron projection; IDA:RGD; .
GO	GO:0043025; C:neuronal cell body; IDA:RGD; .
GO	GO:0043234; C:protein complex; IDA:RGD; .
GO	GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB; .
GO	GO:0005625; C:soluble fraction; IDA:RGD; .
GO	GO:0008021; C:synaptic vesicle; IDA:RGD; .
GO	GO:0043531; F:ADP binding; IDA:RGD; .
GO	GO:0005524; F:ATP binding; IDA:RGD; .
GO	GO:0042623; F:ATPase activity; coupled; IDA:RGD
GO	GO:0005102; F:receptor binding; IPI:RGD; .
GO	GO:0051082; F:unfolded protein binding; IMP:RGD; .
GO	GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:RGD; .
GO	GO:0045892; P:negative regulation of transcription; DNA-dependent; ISS:UniProtKB
GO	GO:0006950; P:response to stress; IEA:UniProtKB-KW; .
GO	GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterPro	IPR018181; Heat_shock_70_CS; .
InterPro	IPR001023; Hsp70; .
InterPro	IPR013126; Hsp_70; .
KO	K03283; -; .
PANTHER	PTHR19375; Hsp70; 1; .
Pfam	PF00012; HSP70; 1; .
PRINTS	PR00301; HEATSHOCK70; .
PROSITE	PS00297; HSP70_1; 1; .
PROSITE	PS00329; HSP70_2; 1; .
PROSITE	PS01036; HSP70_3; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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