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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0014]' for entry matching: HXK1_RAT World-2DPAGE Repository (0014):  HXK1_RAT HXK1_RAT General information about the entry View entry in simple text format Entry name HXK1_RAT Primary accession number P05708 integrated into World-2DPAGE Repository (0014) on  October 13, 2008 (release 1) 2D Annotations were last modified on June 1, 2011 (version 3) General Annotations were last modified on  November 25, 2011 (version 2) Name and origin of the protein Description RecName: Full=Hexokinase-1; EC=2.7.1.1; AltName: Full=Brain form hexokinase; AltName: Full=Hexokinase type I; Short=HK I;. Gene name Name=Hk1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.200900680; Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of whole cerebellum of the mature rat'' Proteomics 10(23):4311-4319 (2010) 2D PAGE maps for identified proteins How to interpret a protein RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum} Rattus norvegicus (Rat) Tissue: Cerebellum   map experimental info   RAT_CEREBELLUM_21D MAP LOCATIONS: SPOT 2680: pI=6.28; Mw=82000   [identification data] IDENTIFICATION: SPOT 2680: SeqCov=38%. MascotPMF=251 [1]. MAPPING (identification): SPOT 2680: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India Cross-references PRIDE 10017. UniProtKB/Swiss-Prot P05708; HXK1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name HXK1_RAT Primary accession number P05708 Sequence was last modified on  May 30, 2000 (version 4) Annotations were last modified on  November 16, 2011 (version 113) Name and origin of the protein Description RecName: Full=Hexokinase-1; EC=2.7.1.1; AltName: Full=Brain form hexokinase; AltName: Full=Hexokinase type I; Short=HK I; Gene name Name=Hk1 Encoded on Name=Hk1 Keywords 3D-structure; Acetylation; Allosteric enzyme; ATP-binding; Complete proteome; Direct protein sequencing; Glycolysis; Kinase; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Transferase. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J04526; AAC20075.1; -; mRNA EMBL U27319; AAC52945.1; -; Genomic_DNA EMBL U89160; AAB71376.1; -; Genomic_DNA EMBL U89158; AAB71374.1; -; Genomic_DNA IPI IPI00202543; -; . PIR A32521; A32521; . PIR B32521; B32521; . PIR C32521; C32521; . PIR C59226; C59226; . RefSeq NP_036866.1; NM_012734.1; . UniGene Rn.11017; -; . PDB 1BG3; X-ray; 2.80 A; A/B=1-918 PDBsum 1BG3; -; . ProteinModelPortal P05708; -; . SMR P05708; 1-911; . PhosphoSite P05708; -; . World-2DPAGE 0004:P05708; -; . PRIDE P05708; -; . GeneID 25058; -; . KEGG rno:25058; -; . CTD 3098; -; . RGD 2796; Hk1; . HOVERGEN HBG005020; -; . PhylomeDB P05708; -; . BRENDA 2.7.1.1; 5301; . NextBio 605272; -; . Genevestigator P05708; -; . GO GO:0005901; C:caveola; IDA:RGD; . GO GO:0005829; C:cytosol; IDA:RGD; . GO GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell; . GO GO:0043234; C:protein complex; IDA:RGD; . GO GO:0005524; F:ATP binding; IDA:RGD; . GO GO:0016887; F:ATPase activity; IC:RGD; . GO GO:0004340; F:glucokinase activity; IDA:RGD; . GO GO:0005536; F:glucose binding; IDA:RGD; . GO GO:0032403; F:protein complex binding; IDA:RGD; . GO GO:0042803; F:protein homodimerization activity; IDA:RGD; . GO GO:0004672; F:protein kinase activity; IDA:RGD; . GO GO:0006096; P:glycolysis; IDA:RGD; . GO GO:0043066; P:negative regulation of apoptosis; IMP:RGD; . GO GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD; . GO GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD; . GO GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD; . GO GO:0046777; P:protein autophosphorylation; IDA:RGD; . GO GO:0010359; P:regulation of anion channel activity; IDA:RGD; . InterPro IPR001312; Hexokinase; . InterPro IPR022673; Hexokinase_C; . InterPro IPR019807; Hexokinase_CS; . InterPro IPR022672; Hexokinase_N; . KO K00844; -; . PANTHER PTHR19443; Hexokinase; 1; . Pfam PF00349; Hexokinase_1; 2; . Pfam PF03727; Hexokinase_2; 2; . PRINTS PR00475; HEXOKINASE; . PROSITE PS00378; HEXOKINASES; 2; . World-2DPAGE Repository (search AC)