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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: IDHP_RAT World-2DPAGE Repository (0022):  IDHP_RAT IDHP_RAT General information about the entry View entry in simple text format Entry name IDHP_RAT Primary accession number P56574 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Isocitrate dehydrogenase [NADP], mitochondrial; Short=IDH; EC=1.1.1.42; AltName: Full=ICD-M; AltName: Full=IDP; AltName: Full=NADP(+)-specific ICDH; AltName: Full=Oxalosuccinate decarboxylase; Flags: Precursor;. Gene name Name=Idh2 Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 129: pI=8.88; Mw=51391   [identification data] SPOT 243: pI=8.88; Mw=51391   [identification data] IDENTIFICATION: SPOT 129: SeqCov=31%. Peptides MS=14/20. Mascot PMF Score=130 [1] SPOT 243: SeqCov=28.3%. Peptides MS=12/20. Mascot PMF Score=102 [1]. PEPTIDE EVIDENCE: SPOT 243: 283-IWYEHR-288 (32) / 81-YFDLGLPNR-89 (39) / 160-LVPGWTKPITIGR-172 (17) [1]. MAPPING (identification): SPOT 129: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 243: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P56574; IDHP_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name IDHP_RAT Primary accession number P56574 Secondary accession number(s) Q6DGF1 Sequence was last modified on  December 12, 2006 (version 2) Annotations were last modified on  November 16, 2011 (version 77) Name and origin of the protein Description RecName: Full=Isocitrate dehydrogenase [NADP], mitochondrial; Short=IDH; EC=1.1.1.42; AltName: Full=ICD-M; AltName: Full=IDP; AltName: Full=NADP(+)-specific ICDH; AltName: Full=Oxalosuccinate decarboxylase; Flags: Precursor; Gene name Name=Idh2 Encoded on Name=Idh2 Keywords Acetylation; Complete proteome; Direct protein sequencing; Glyoxylate bypass; Magnesium; Manganese; Metal-binding; Mitochondrion; NADP; Oxidoreductase; Reference proteome; Transit peptide; Tricarboxylic acid cycle. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC076398; AAH76398.1; -; mRNA IPI IPI00193485; -; . RefSeq NP_001014183.1; NM_001014161.1; . UniGene Rn.3490; -; . ProteinModelPortal P56574; -; . SMR P56574; 40-452; . IntAct P56574; 1; . MINT MINT-1794004; -; . STRING P56574; -; . PhosphoSite P56574; -; . PRIDE P56574; -; . Ensembl ENSRNOT00000019059; ENSRNOP00000019059; ENSRNOG00000013949; . GeneID 361596; -; . KEGG rno:361596; -; . CTD 3418; -; . RGD 1597139; Idh2; . eggNOG roNOG09103; -; . GeneTree ENSGT00390000012547; -; . HOVERGEN HBG006119; -; . InParanoid P56574; -; . OMA HKIWYEH; -; . OrthoDB EOG42V8G4; -; . PhylomeDB P56574; -; . NextBio 676849; -; . ArrayExpress P56574; -; . Genevestigator P56574; -; . GO GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB; . GO GO:0000287; F:magnesium ion binding; ISS:UniProtKB; . GO GO:0051287; F:NAD binding; IEA:InterPro; . GO GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB; . GO GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW; . GO GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB; . GO GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW; . InterPro IPR019818; IsoCit/isopropylmalate_DH_CS; . InterPro IPR004790; Isocitrate_DH_NADP_euk-typ; . InterPro IPR024084; IsoPropMal-DH-like_dom; . Gene3D G3DSA:3.40.718.10; IDH_IMDH; 1; . KO K00031; -; . PANTHER PTHR11822; IDH_NADP_euk; 1; . Pfam PF00180; Iso_dh; 1; . PIRSF PIRSF000108; IDH_NADP; 1; . TIGRFAMs TIGR00127; Nadp_idh_euk; 1; . PROSITE PS00470; IDH_IMDH; 1; . World-2DPAGE Repository (search AC)