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World-2DPAGE Repository
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SWISS-2DPAGE
World-2DPAGE Portal
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Searching in 'World-2DPAGE Repository [0014]' for entry
matching:
IF5A1_RAT
World-2DPAGE Repository
(0014):
IF5A1_RAT
IF5A1_RAT
General information about the entry
View entry in simple text format
Entry name
IF5A1_RAT
Primary accession number
Q3T1J1
integrated into World-2DPAGE Repository (0014) on
October 13, 2008 (release 1)
2D Annotations were last modified on
June 1, 2011 (version 3)
General Annotations were last modified on
November 25, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=eIF-4D;.
Gene name
Name=Eif5a
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.200900680
;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
RAT_CEREBELLUM_21D
{Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
map experimental info
RAT_CEREBELLUM_21D
MAP LOCATIONS:
SPOT 3269
:
pI=5.30; Mw=16000
[identification data]
IDENTIFICATION:
SPOT 3269: SeqCov=46%. MascotPMF=75 [
1
].
MAPPING (identification):
SPOT
3269
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE
10017.
UniProtKB/Swiss-Prot
Q3T1J1; IF5A1_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
IF5A1_RAT
Primary accession number
Q3T1J1
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
November 16, 2011 (version 61)
Name and origin of the protein
Description
RecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=eIF-4D;
Gene name
Name=Eif5a
Encoded on
Name=Eif5a
Keywords
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Elongation factor
;
Endoplasmic reticulum
;
Hypusine
;
Membrane
;
mRNA transport
;
Nuclear pore complex
;
Nucleus
;
Phosphoprotein
;
Protein biosynthesis
;
Protein transport
;
Reference proteome
;
RNA-binding
;
Translocation
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
BC101891; AAI01892.1
; -; mRNA
IPI
IPI00211216; -
; .
RefSeq
NP_001028853.1; NM_001033681.1
; .
UniGene
Rn.128212; -
; .
ProteinModelPortal
Q3T1J1; -
; .
SMR
Q3T1J1; 15-150
; .
IntAct
Q3T1J1; 1
; .
STRING
Q3T1J1; -
; .
PhosphoSite
Q3T1J1; -
; .
PRIDE
Q3T1J1; -
; .
Ensembl
ENSRNOT00000022343; ENSRNOP00000022343
; ENSRNOG00000016478; .
GeneID
287444; -
; .
KEGG
rno:287444; -
; .
UCSC
NM_001033681; rat
; .
CTD
1984; -
; .
RGD
1308029; Eif5a
; .
eggNOG
maNOG16112; -
; .
GeneTree
ENSGT00390000003738; -
; .
HOVERGEN
HBG001104; -
; .
InParanoid
Q3T1J1; -
; .
OMA
NGDLRED; -
; .
OrthoDB
EOG41JZDF; -
; .
PhylomeDB
Q3T1J1; -
; .
NextBio
626163; -
; .
ArrayExpress
Q3T1J1; -
; .
Genevestigator
Q3T1J1; -
; .
GermOnline
ENSRNOG00000016478; Rattus norvegicus
; .
GO
GO:0030425; C:dendrite
; IDA:RGD; .
GO
GO:0005789; C:endoplasmic reticulum membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0043025; C:neuronal cell body
; IDA:RGD; .
GO
GO:0005643; C:nuclear pore
; IEA:UniProtKB-SubCell; .
GO
GO:0043022; F:ribosome binding
; IEA:InterPro; .
GO
GO:0003746; F:translation elongation factor activity
; IEA:UniProtKB-KW; .
GO
GO:0007568; P:aging
; IEP:RGD; .
GO
GO:0051028; P:mRNA transport
; IEA:UniProtKB-KW; .
GO
GO:0043066; P:negative regulation of apoptosis
; IMP:RGD; .
GO
GO:0008612; P:peptidyl-lysine modification to hypusine
; IEA:InterPro; .
GO
GO:0051149; P:positive regulation of muscle cell differentiation
; IMP:RGD; .
GO
GO:0045901; P:positive regulation of translational elongation
; IEA:InterPro; .
GO
GO:0045905; P:positive regulation of translational termination
; IEA:InterPro; .
GO
GO:0015031; P:protein transport
; IEA:UniProtKB-KW; .
GO
GO:0006452; P:translational frameshifting
; IEA:InterPro; .
InterPro
IPR005824; KOW
; .
InterPro
IPR012340; NA-bd_OB-fold
; .
InterPro
IPR016027; NA-bd_OB-fold-like
; .
InterPro
IPR019769; Trans_elong_IF5A_hypusine_site
; .
InterPro
IPR001884; Transl_elong_IF5A
; .
InterPro
IPR020189; Transl_elong_IF5A_C
; .
InterPro
IPR014722; Transl_SH3-like_sub
; .
InterPro
IPR008991; Translation_prot_SH3-like
; .
Gene3D
G3DSA:2.40.50.140; OB_NA_bd_sub
; 1; .
Gene3D
G3DSA:2.30.30.30; Ribosomal_L2
; 1; .
KO
K03263; -
; .
PANTHER
PTHR11673; EIF5A_hypusine
; 1; .
Pfam
PF01287; eIF-5a
; 1; .
Pfam
PF00467; KOW
; 1; .
PIRSF
PIRSF003025; eIF5A
; 1; .
SUPFAM
SSF50249; Nucleic_acid_OB
; 1; .
SUPFAM
SSF50104; Transl_SH3_like
; 1; .
TIGRFAMs
TIGR00037; EIF_5A
; 1; .
PROSITE
PS00302; IF5A_HYPUSINE
; 1; .
World-2DPAGE Repository (search AC)
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