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Searching in 'World-2DPAGE Repository [0030]' for entry matching: ITPR2_RAT




World-2DPAGE Repository (0030):  ITPR2_RAT


ITPR2_RAT


General information about the entry
View entry in simple text format
Entry nameITPR2_RAT
Primary accession numberP29995
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Inositol 1,4,5-trisphosphate receptor type 2; AltName: Full=IP3 receptor isoform 2; Short=IP3R 2; Short=InsP3R2; AltName: Full=Type 2 inositol 1,4,5-trisphosphate receptor; Short=Type 2 InsP3 receptor;.
Gene nameName=Itpr2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info
 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=6.41; Mw=69448  [identification data]

IDENTIFICATION: SPOT 798: Mascot protein score=32. Number of peptides=3 [1].
MAPPING (identification):
SPOT 798: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtP29995; ITPR2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameITPR2_RAT
Primary accession numberP29995
Secondary accession number(s) Q99P56
Sequence was last modified on April 1, 1993 (version 1)
Annotations were last modified on November 16, 2011 (version 99)
Name and origin of the protein
DescriptionRecName: Full=Inositol 1,4,5-trisphosphate receptor type 2; AltName: Full=IP3 receptor isoform 2; Short=IP3R 2; Short=InsP3R2; AltName: Full=Type 2 inositol 1,4,5-trisphosphate receptor; Short=Type 2 InsP3 receptor;
Gene nameName=Itpr2
Encoded onName=Itpr2
KeywordsAcetylation; Calcium; Calcium channel; Calcium transport; Complete proteome; Endoplasmic reticulum; Ion transport; Ionic channel; Ligand-gated ion channel; Membrane; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX61677; CAA43852.1; -; mRNA
EMBLAF329470; AAK11622.1; -; mRNA
IPIIPI00324177; -; .
PIRS17796; S17796; .
RefSeqNP_112308.1; NM_031046.3; .
UniGeneRn.89152; -; .
ProteinModelPortalP29995; -; .
SMRP29995; 7-225; 236-602; .
STRINGP29995; -; .
TCDB1.A.3.2.1; ryanodine-inositol 1; 4; 5-triphosphate receptor Ca2+ channel (RIR-CaC) family
PRIDEP29995; -; .
GeneID81678; -; .
KEGGrno:81678; -; .
CTD3709; -; .
RGD69649; Itpr2; .
eggNOGroNOG05144; -; .
HOVERGENHBG052158; -; .
ReactomeREACT_111984; Signal Transduction; .
ReactomeREACT_113568; Metabolism; .
NextBio615288; -; .
GenevestigatorP29995; -; .
GOGO:0030424; C:axon; IDA:RGD; .
GOGO:0016021; C:integral to membrane; IEA:UniProtKB-KW; .
GOGO:0043209; C:myelin sheath; IDA:RGD; .
GOGO:0005220; F:inositol 1; 4; 5-trisphosphate-sensitive calcium-release channel activity
IEA:InterPro.
InterProIPR000699; Ca-rel_channel; .
InterProIPR014821; Ins145_P3_rcpt; .
InterProIPR000493; InsP3_rcpt-bd; .
InterProIPR005821; Ion_trans; .
InterProIPR003608; MIR; .
InterProIPR016093; MIR_motif; .
InterProIPR013662; RIH_assoc-dom; .
InterProIPR015925; Ryanodine_recept-rel; .
KOK04959; -; .
PANTHERPTHR13715; Ryanodine_recept-rel; 1; .
PfamPF08709; Ins145_P3_rec; 1; .
PfamPF00520; Ion_trans; 1; .
PfamPF02815; MIR; 1; .
PfamPF08454; RIH_assoc; 1; .
PfamPF01365; RYDR_ITPR; 2; .
PRINTSPR00779; INSP3RECEPTR; .
SMARTSM00472; MIR; 4; .
SUPFAMSSF82109; MIR; 2; .
PROSITEPS50919; MIR; 5; .



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