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Searching in 'World-2DPAGE Repository [0022]' for entry matching: KNT1_RAT




World-2DPAGE Repository (0022):  KNT1_RAT

KNT1_RAT


General information about the entry
View entry in simple text format
Entry nameKNT1_RAT
Primary accession numberP01048
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=T-kininogen 1; AltName: Full=Alpha-1-MAP; AltName: Full=Major acute phase protein; AltName: Full=T-kininogen I; AltName: Full=Thiostatin; Contains: RecName: Full=T-kininogen 1 heavy chain; AltName: Full=T-kininogen I heavy chain; Contains: RecName: Full=T-kinin; Contains: RecName: Full=T-kininogen 1 light chain; AltName: Full=T-kininogen I light chain; Flags: Precursor;.
Gene nameName=Map1
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info 		 
HCR_LCR_HEART

MAP LOCATIONS:
pI=6.63; Mw=58294  [identification data]
pI=6.08; Mw=48828  [identification data]
pI=6.63; Mw=58294  [identification data]

IDENTIFICATION: SPOT 278: SeqCov=33%. Peptides MS=16/20. Mascot PMF Score=153 [1]
SPOT 279: SeqCov=13.5%. Peptides MS=6/20. Mascot PMF Score=41 [1]; SPOT 404: SeqCov=37.1%. Peptides MS=18/20. Mascot PMF Score=190 [1].
PEPTIDE EVIDENCE: SPOT 279: 172-HTHLFALR-179 (50) / 44-YNAELESGNQFVLYR-58 (57) [1].
MAPPING (identification):
SPOT 278: Peptide mass fingerprinting [1];
SPOT 279: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 404: Peptide mass fingerprinting [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP01048; KNT1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameKNT1_RAT
Primary accession numberP01048
Secondary accession number(s) P04081 Q6LDW3
Sequence was last modified on February 1, 2005 (version 2)
Annotations were last modified on November 16, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=T-kininogen 1; AltName: Full=Alpha-1-MAP; AltName: Full=Major acute phase protein; AltName: Full=T-kininogen I; AltName: Full=Thiostatin; Contains: RecName: Full=T-kininogen 1 heavy chain; AltName: Full=T-kininogen I heavy chain; Contains: RecName: Full=T-kinin; Contains: RecName: Full=T-kininogen 1 light chain; AltName: Full=T-kininogen I light chain; Flags: Precursor;
Gene nameName=Map1
Encoded onName=Map1
KeywordsAcute phase; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Protease inhibitor; Pyrrolidone carboxylic acid; Reference proteome; Repeat; Secreted; Signal; Thiol protease inhibitor; Vasoactive; Vasodilator.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM11883; AAA41489.1; -; mRNA
EMBLM16454; AAA41568.1; -; Genomic_DNA
EMBLM14356; AAA41492.1; -; Genomic_DNA
EMBLX02299; CAA26162.1; ALT_SEQ; mRNA
IPIIPI00950893; -; .
PIRA01285; KGRTM; .
PIRA01286; KGRTT1; .
PIRA23897; A23897; .
PIRA27115; A27115; .
UniGeneRn.128333; -; .
ProteinModelPortalP01048; -; .
STRINGP01048; -; .
MEROPSI25.019; -; .
GlycoSuiteDBP01048; -; .
PRIDEP01048; -; .
UCSCNM_012696; rat; .
eggNOGroNOG04293; -; .
HOVERGENHBG006224; -; .
OrthoDBEOG4QNMVT; -; .
PMAP-CutDBP01048; -; .
ArrayExpressP01048; -; .
GenevestigatorP01048; -; .
GermOnlineENSRNOG00000031231; Rattus norvegicus; .
GOGO:0005615; C:extracellular space; IEA:UniProtKB-SubCell; .
GOGO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW; .
GOGO:0006953; P:acute-phase response; IEA:UniProtKB-KW; .
GOGO:0042311; P:vasodilation; IEA:UniProtKB-KW; .
InterProIPR000010; Prot_inh_cystat; .
InterProIPR018073; Prot_inh_cystat_CS; .
PfamPF00031; Cystatin; 3; .
SMARTSM00043; CY; 3; .
PROSITEPS00287; CYSTATIN; 2; .


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