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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: LGUL_RAT World-2DPAGE Repository (0030):  LGUL_RAT LGUL_RAT General information about the entry View entry in simple text format Entry name LGUL_RAT Primary accession number Q6P7Q4 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Lactoylglutathione lyase; EC=4.4.1.5; AltName: Full=Aldoketomutase; AltName: Full=Glyoxalase I; Short=Glx I; AltName: Full=Ketone-aldehyde mutase; AltName: Full=Methylglyoxalase; AltName: Full=S-D-lactoylglutathione methylglyoxal lyase;. Gene name Name=Glo1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 2176: pI=4.87; Mw=27072   [identification data] IDENTIFICATION: SPOT 2176: Mascot protein score=364. Number of peptides=6 [1]. MAPPING (identification): SPOT 2176: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot Q6P7Q4; LGUL_RAT. World-2DPAGE Repository Q6P7Q4; LGUL_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name LGUL_RAT Primary accession number Q6P7Q4 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 68) Name and origin of the protein Description RecName: Full=Lactoylglutathione lyase; EC=4.4.1.5; AltName: Full=Aldoketomutase; AltName: Full=Glyoxalase I; Short=Glx I; AltName: Full=Ketone-aldehyde mutase; AltName: Full=Methylglyoxalase; AltName: Full=S-D-lactoylglutathione methylglyoxal lyase; Gene name Name=Glo1 Encoded on Name=Glo1 Keywords Acetylation; Complete proteome; Direct protein sequencing; Disulfide bond; Glutathionylation; Lyase; Metal-binding; Phosphoprotein; Reference proteome; Zinc. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC061570; AAH61570.1; -; mRNA IPI IPI00188304; -; . RefSeq NP_997477.1; NM_207594.1; . UniGene Rn.108014; -; . ProteinModelPortal Q6P7Q4; -; . SMR Q6P7Q4; 4-183; . STRING Q6P7Q4; -; . PRIDE Q6P7Q4; -; . Ensembl ENSRNOT00000000650; ENSRNOP00000000650; ENSRNOG00000000541; . GeneID 294320; -; . KEGG rno:294320; -; . NMPDR fig|10116.3.peg.17657; -; . UCSC NM_207594; rat; . CTD 2739; -; . RGD 2702; Glo1; . eggNOG roNOG12414; -; . GeneTree ENSGT00390000009312; -; . HOVERGEN HBG025852; -; . InParanoid Q6P7Q4; -; . OMA WMKSIPG; -; . OrthoDB EOG4TQMB3; -; . PhylomeDB Q6P7Q4; -; . NextBio 637974; -; . ArrayExpress Q6P7Q4; -; . Genevestigator Q6P7Q4; -; . GermOnline ENSRNOG00000000541; Rattus norvegicus; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0004462; F:lactoylglutathione lyase activity; ISS:UniProtKB; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0006916; P:anti-apoptosis; ISS:UniProtKB; . GO GO:0005975; P:carbohydrate metabolic process; IDA:RGD; . GO GO:0006749; P:glutathione metabolic process; IDA:RGD; . GO GO:0009438; P:methylglyoxal metabolic process; IDA:RGD; . InterPro IPR004360; Glyas_Fos-R_dOase; . InterPro IPR004361; Glyoxalase_1; . InterPro IPR018146; Glyoxalase_1_CS; . KO K01759; -; . Pfam PF00903; Glyoxalase; 1; . TIGRFAMs TIGR00068; Glyox_I; 1; . PROSITE PS00934; GLYOXALASE_I_1; 1; . PROSITE PS00935; GLYOXALASE_I_2; 1; . World-2DPAGE Repository (search AC)