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Searching in 'World-2DPAGE Repository [0004]' for entry matching: LIS1_RAT




World-2DPAGE Repository (0004):  LIS1_RAT

LIS1_RAT


General information about the entry
View entry in simple text format
Entry nameLIS1_RAT
Primary accession numberP63004
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha; AltName: Full=Lissencephaly-1 protein; Short=LIS-1; AltName: Full=PAF acetylhydrolase 45 kDa subunit; Short=PAF-AH 45 kDa subunit; AltName: Full=PAF-AH alpha; Short=PAFAH alpha;.
Gene nameName=Pafah1b1
Synonyms=Lis-1, Lis1, Pafaha
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   MAPPING ON GEL
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
OB21DSUB
  map experimental info 		 
OB21DSUB

MAP LOCATIONS:
pI=6.90; Mw=46000  [identification data]

MAPPING (identification):
SPOT 408: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-ProtP63004; LIS1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameLIS1_RAT
Primary accession numberP63004
Secondary accession number(s) O35592 P43035 P81692 Q9R2A6
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on November 16, 2011 (version 74)
Name and origin of the protein
DescriptionRecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha; AltName: Full=Lissencephaly-1 protein; Short=LIS-1; AltName: Full=PAF acetylhydrolase 45 kDa subunit; Short=PAF-AH 45 kDa subunit; AltName: Full=PAF-AH alpha; Short=PAFAH alpha;
Gene nameName=Pafah1b1
Synonyms=Lis-1, Lis1, Pafaha
Encoded onName=Pafah1b1; Synonyms=Lis-1, Lis1, Pafaha
KeywordsAcetylation; Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Differentiation; Lipid degradation; Membrane; Microtubule; Mitosis; Neurogenesis; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transport; WD repeat.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF016049; AAC27975.1; -; mRNA
EMBLBC072510; AAH72510.1; -; mRNA
IPIIPI00231298; -; .
RefSeqNP_113951.1; NM_031763.3; .
UniGeneRn.5827; -; .
ProteinModelPortalP63004; -; .
SMRP63004; 1-79; 92-408; .
IntActP63004; 1; .
STRINGP63004; -; .
PhosphoSiteP63004; -; .
World-2DPAGE0004:P63004; -; .
PRIDEP63004; -; .
GeneID83572; -; .
KEGGrno:83572; -; .
CTD5048; -; .
RGD620331; Pafah1b1; .
eggNOGroNOG12220; -; .
GeneTreeENSGT00600000084302; -; .
HOVERGENHBG006271; -; .
InParanoidP63004; -; .
OrthoDBEOG4P5K93; -; .
PhylomeDBP63004; -; .
NextBio616071; -; .
ArrayExpressP63004; -; .
GenevestigatorP63004; -; .
GermOnlineENSRNOG00000002755; Rattus norvegicus; .
GOGO:0033267; C:axon part; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0030426; C:growth cone; IDA:RGD; .
GOGO:0005871; C:kinesin complex; IDA:RGD; .
GOGO:0043025; C:neuronal cell body; IDA:RGD; .
GOGO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0042598; C:vesicular fraction; IDA:RGD; .
GOGO:0045505; F:dynein intermediate chain binding; IDA:RGD; .
GOGO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD; .
GOGO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD; .
GOGO:0051660; P:establishment of centrosome localization; IMP:RGD; .
GOGO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW; .
GOGO:0007067; P:mitosis; IEA:UniProtKB-KW; .
GOGO:0010977; P:negative regulation of neuron projection development; IMP:RGD; .
GOGO:0001764; P:neuron migration; IMP:RGD; .
GOGO:0007097; P:nuclear migration; IMP:RGD; .
GOGO:0045773; P:positive regulation of axon extension; IMP:RGD; .
GOGO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD; .
GOGO:0017145; P:stem cell division; IMP:RGD; .
InterProIPR017252; Dynein_regulator; .
InterProIPR020472; G-protein_beta_WD-40_rep; .
InterProIPR006594; LisH_dimerisation; .
InterProIPR013720; LisH_dimerisation_subgr; .
InterProIPR015943; WD40/YVTN_repeat-like_dom; .
InterProIPR001680; WD40_repeat; .
InterProIPR011046; WD40_repeat-like_dom; .
InterProIPR019782; WD40_repeat_2; .
InterProIPR019775; WD40_repeat_CS; .
InterProIPR017986; WD40_repeat_dom; .
InterProIPR019781; WD40_repeat_subgr; .
Gene3DG3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1; .
KOK01062; -; .
PANTHERPTHR22847:SF51; PTHR22847:SF51; 1; .
PfamPF08513; LisH; 1; .
PfamPF00400; WD40; 7; .
PIRSFPIRSF037647; Dynein_regulator_Lis1; 1; .
PRINTSPR00320; GPROTEINBRPT; .
SMARTSM00667; LisH; 1; .
SMARTSM00320; WD40; 7; .
SUPFAMSSF50978; WD40_like; 1; .
PROSITEPS50896; LISH; 1; .
PROSITEPS00678; WD_REPEATS_1; 4; .
PROSITEPS50082; WD_REPEATS_2; 7; .
PROSITEPS50294; WD_REPEATS_REGION; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server