World-2DPAGE Repository
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World-2DPAGE Repository
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Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0004]' for entry
matching:
MDHC_RAT
World-2DPAGE Repository
(0004):
MDHC_RAT
MDHC_RAT
General information about the entry
View entry in simple text format
Entry name
MDHC_RAT
Primary accession number
O88989
integrated into World-2DPAGE Repository (0004) on
October 13, 2008 (release 1)
2D Annotations were last modified on
May 18, 2011 (version 2)
General Annotations were last modified on
December 22, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Malate dehydrogenase, cytoplasmic; EC=1.1.1.37; AltName: Full=Cytosolic malate dehydrogenase;.
Gene name
Name=Mdh1
Synonyms=Mdh
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
MAPPING ON GEL
PubMed=19343716; DOI=
10.1002/pmic.200800664
; [
NCBI
,
EBI
,
Israel
,
Japan
]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein
OB21DSUB
{2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
map experimental info
OB21DSUB
MAP LOCATIONS:
SPOT 527
:
pI=5.77; Mw=37000
[identification data]
SPOT 528
:
pI=5.92; Mw=37000
[identification data]
MAPPING (identification):
SPOT
527
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
528
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-Prot
O88989; MDHC_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
MDHC_RAT
Primary accession number
O88989
Secondary accession number(s)
O88585 Q6PCV2
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
November 16, 2011 (version 84)
Name and origin of the protein
Description
RecName: Full=Malate dehydrogenase, cytoplasmic; EC=1.1.1.37; AltName: Full=Cytosolic malate dehydrogenase;
Gene name
Name=Mdh1
Synonyms=Mdh
Encoded on
Name=Mdh1; Synonyms=Mdh
Keywords
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
NAD
;
Oxidoreductase
;
Phosphoprotein
;
Reference proteome
;
Tricarboxylic acid cycle
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF093773; AAC64180.1
; -; mRNA
EMBL
BC059124; AAH59124.1
; -; mRNA
EMBL
AF075574; AAC26799.1
; -; mRNA
IPI
IPI00198717; -
; .
RefSeq
NP_150238.1; NM_033235.1
; .
UniGene
Rn.13492; -
; .
ProteinModelPortal
O88989; -
; .
SMR
O88989; 2-334
; .
IntAct
O88989; 1
; .
STRING
O88989; -
; .
PhosphoSite
O88989; -
; .
World-2DPAGE
0004:O88989; -
; .
PRIDE
O88989; -
; .
Ensembl
ENSRNOT00000011429; ENSRNOP00000011429
; ENSRNOG00000008103; .
GeneID
24551; -
; .
KEGG
rno:24551; -
; .
NMPDR
fig|10116.3.peg.10844; -
; .
UCSC
NM_033235; rat
; .
CTD
4190; -
; .
RGD
3072; Mdh1
; .
eggNOG
roNOG11216; -
; .
GeneTree
ENSGT00530000063410; -
; .
HOVERGEN
HBG006340; -
; .
InParanoid
O88989; -
; .
OrthoDB
EOG4CVG78; -
; .
PhylomeDB
O88989; -
; .
NextBio
603654; -
; .
ArrayExpress
O88989; -
; .
Genevestigator
O88989; -
; .
GermOnline
ENSRNOG00000008103; Rattus norvegicus
; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0030060; F:L-malate dehydrogenase activity
; IDA:RGD; .
GO
GO:0051287; F:NAD binding
; IDA:RGD; .
GO
GO:0044262; P:cellular carbohydrate metabolic process
; IEA:InterPro; .
GO
GO:0006108; P:malate metabolic process
; IDA:RGD; .
GO
GO:0006734; P:NADH metabolic process
; IDA:RGD; .
GO
GO:0006107; P:oxaloacetate metabolic process
; IDA:RGD; .
GO
GO:0006099; P:tricarboxylic acid cycle
; IEA:UniProtKB-KW; .
InterPro
IPR001557; L-lactate/malate_DH
; .
InterPro
IPR022383; Lactate/malate_DH_C
; .
InterPro
IPR001236; Lactate/malate_DH_N
; .
InterPro
IPR015955; Lactate_DH/Glyco_Ohase_4_C
; .
InterPro
IPR001252; Malate_DH_AS
; .
InterPro
IPR011274; Malate_DH_NAD-dep_euk
; .
InterPro
IPR010945; Malate_DH_type2
; .
InterPro
IPR016040; NAD(P)-bd_dom
; .
Gene3D
G3DSA:3.90.110.10; lact_mal_DH
; 1; .
Gene3D
G3DSA:3.40.50.720; NAD(P)-bd
; 1; .
KO
K00025; -
; .
PANTHER
PTHR23382; MDH_SF1
; 1; .
Pfam
PF02866; Ldh_1_C
; 1; .
Pfam
PF00056; Ldh_1_N
; 1; .
PIRSF
PIRSF000102; Lac_mal_DH
; 1; .
SUPFAM
SSF56327; Lactate_DH/Glyco_hydro_4_C
; 1; .
TIGRFAMs
TIGR01759; MalateDH-SF1
; 1; .
TIGRFAMs
TIGR01758; MDH_euk_cyt
; 1; .
PROSITE
PS00068; MDH
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server