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Searching in 'World-2DPAGE Repository [0019]' for entry matching: NDUS1_RAT

World-2DPAGE Repository (0019):  NDUS1_RAT


General information about the entry
View entry in simple text format
Entry nameNDUS1_RAT
Primary accession numberQ66HF1
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; EC=; EC=; Flags: Precursor;.
Gene nameName=Ndufs1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=5.65; Mw=80330  [identification data]
pI=5.65; Mw=80330  [identification data]

IDENTIFICATION: SPOT 252: Peptides number=5. SeqCov=10.6%. MOWSE score=4.97E+4 [1]
SPOT 253: Peptides number=9. SeqCov=15.3%. MOWSE score=8.75E+7 [1].
MAPPING (identification):
SPOT 252: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 253: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtQ66HF1; NDUS1_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameNDUS1_RAT
Primary accession numberQ66HF1
Sequence was last modified on October 11, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 64)
Name and origin of the protein
DescriptionRecName: Full=NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; EC=; EC=; Flags: Precursor;
Gene nameName=Ndufs1
Encoded onName=Ndufs1
Keywords2Fe-2S; 4Fe-4S; Acetylation; Complete proteome; Direct protein sequencing; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Reference proteome; Respiratory chain; Transit peptide; Transport; Ubiquinone.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLBC081892; AAH81892.1; -; mRNA
IPIIPI00358033; -; .
RefSeqNP_001005550.1; NM_001005550.1; .
UniGeneRn.1467; -; .
HSSPQ56223; 2FUG; .
ProteinModelPortalQ66HF1; -; .
STRINGQ66HF1; -; .
PhosphoSiteQ66HF1; -; .
PRIDEQ66HF1; -; .
EnsemblENSRNOT00000015852; ENSRNOP00000015851; ENSRNOG00000011849; .
GeneID301458; -; .
KEGGrno:301458; -; .
NMPDRfig|10116.3.peg.30141; -; .
UCSCNM_001005550; rat; .
CTD4719; -; .
RGD1359670; Ndufs1; .
eggNOGroNOG09474; -; .
GeneTreeENSGT00390000018768; -; .
HOVERGENHBG003482; -; .
InParanoidQ66HF1; -; .
OrthoDBEOG4D26PC; -; .
PhylomeDBQ66HF1; -; .
NextBio648791; -; .
ArrayExpressQ66HF1; -; .
GenevestigatorQ66HF1; -; .
GOGO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB; .
GOGO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB; .
GOGO:0051537; F:2 iron; 2 sulfur cluster binding; IEA:UniProtKB-KW
GOGO:0051539; F:4 iron; 4 sulfur cluster binding; IEA:UniProtKB-KW
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IBA:RefGenome; .
GOGO:0006915; P:apoptotic process; ISS:UniProtKB; .
GOGO:0046034; P:ATP metabolic process; ISS:UniProtKB; .
GOGO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro; .
GOGO:0072593; P:reactive oxygen species metabolic process; ISS:UniProtKB; .
GOGO:0051881; P:regulation of mitochondrial membrane potential; ISS:UniProtKB; .
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
InterProIPR012675; Beta-grasp_ferredoxin-type; .
InterProIPR001041; Ferredoxin; .
InterProIPR006656; Mopterin_OxRdtase; .
InterProIPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS; .
InterProIPR010228; NADH_UbQ_OxRdtase_Gsu; .
InterProIPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd; .
InterProIPR015405; NuoG_C; .
Gene3DG3DSA:; Ferredoxin_fold; 1; .
KOK03934; -; .
PfamPF09326; DUF1982; 1; .
PfamPF00111; Fer2; 1; .
PfamPF00384; Molybdopterin; 1; .
PfamPF10588; NADH-G_4Fe-4S_3; 1; .
SMARTSM00929; NADH-G_4Fe-4S_3; 1; .
SUPFAMSSF54292; Ferredoxin; 1; .
TIGRFAMsTIGR01973; NuoG; 1; .
PROSITEPS51085; 2FE2S_FER_2; 1; .
PROSITEPS00641; COMPLEX1_75K_1; 1; .
PROSITEPS00642; COMPLEX1_75K_2; 1; .
PROSITEPS00643; COMPLEX1_75K_3; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server