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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: NPM_RAT World-2DPAGE Repository (0030):  NPM_RAT NPM_RAT General information about the entry View entry in simple text format Entry name NPM_RAT Primary accession number P13084 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;. Gene name Name=Npm1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 1555: pI=4.67; Mw=44422   [identification data] SPOT 1557: pI=4.70; Mw=44300   [identification data] IDENTIFICATION: SPOT 1555: Mascot protein score=135. Number of peptides=5 [1] SPOT 1557: Mascot protein score=109. Number of peptides=4 [1]. MAPPING (identification): SPOT 1555: Tandem mass spectrometry [1]; SPOT 1557: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot P13084; NPM_RAT. World-2DPAGE Repository P13084; NPM_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name NPM_RAT Primary accession number P13084 Secondary accession number(s) Q63698 Q64269 Sequence was last modified on  January 1, 1990 (version 1) Annotations were last modified on  November 16, 2011 (version 98) Name and origin of the protein Description RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin; Gene name Name=Npm1 Encoded on Name=Npm1 Keywords Acetylation; ADP-ribosylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disulfide bond; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J03969; AAA40796.1; -; mRNA EMBL M37039; AAA41730.1; -; Genomic_DNA EMBL M37035; AAA41730.1; JOINED; Genomic_DNA EMBL M37036; AAA41730.1; JOINED; Genomic_DNA EMBL M37037; AAA41730.1; JOINED; Genomic_DNA EMBL M37038; AAA41730.1; JOINED; Genomic_DNA EMBL M37041; AAA41731.1; -; Genomic_DNA EMBL M37035; AAA41731.1; JOINED; Genomic_DNA EMBL M37036; AAA41731.1; JOINED; Genomic_DNA EMBL M37037; AAA41731.1; JOINED; Genomic_DNA EMBL M37038; AAA41731.1; JOINED; Genomic_DNA EMBL M37040; AAA41731.1; JOINED; Genomic_DNA EMBL M25062; AAA40795.1; -; Genomic_DNA EMBL J04943; AAA40794.1; -; mRNA EMBL J04944; AAA40793.1; -; Genomic_DNA EMBL BC060579; AAH60579.1; -; mRNA EMBL BC088088; AAH88088.1; -; mRNA IPI IPI00197553; -; . IPI IPI00230893; -; . PIR A28939; A28939; . PIR A36089; A36089; . PIR B36089; A34168; . RefSeq NP_037124.1; NM_012992.3; . UniGene Rn.54537; -; . ProteinModelPortal P13084; -; . SMR P13084; 15-118; 241-292; . STRING P13084; -; . PhosphoSite P13084; -; . World-2DPAGE 0004:P13084; -; . PRIDE P13084; -; . Ensembl ENSRNOT00000006591; ENSRNOP00000006591; ENSRNOG00000004616; . Ensembl ENSRNOT00000064744; ENSRNOP00000062356; ENSRNOG00000004616; . GeneID 25498; -; . KEGG rno:25498; -; . UCSC NM_012992; rat; . CTD 4869; -; . RGD 3192; Npm1; . eggNOG roNOG11600; -; . GeneTree ENSGT00440000034554; -; . HOVERGEN HBG001860; -; . InParanoid P13084; -; . OMA NCFRTED; -; . OrthoDB EOG4W3SNZ; -; . PhylomeDB P13084; -; . NextBio 606897; -; . ArrayExpress P13084; -; . Genevestigator P13084; -; . GermOnline ENSRNOG00000004616; Rattus norvegicus; . GO GO:0005813; C:centrosome; ISS:UniProtKB; . GO GO:0005730; C:nucleolus; IDA:RGD; . GO GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell; . GO GO:0003677; F:DNA binding; IDA:RGD; . GO GO:0019899; F:enzyme binding; IDA:RGD; . GO GO:0051059; F:NF-kappaB binding; ISS:UniProtKB; . GO GO:0005547; F:phosphatidylinositol-3; 4; 5-trisphosphate binding IPI:RGD . GO GO:0003723; F:RNA binding; IEA:UniProtKB-KW; . GO GO:0051082; F:unfolded protein binding; ISS:UniProtKB; . GO GO:0007569; P:cell aging; ISS:UniProtKB; . GO GO:0007098; P:centrosome cycle; ISS:UniProtKB; . GO GO:0006281; P:DNA repair; ISS:UniProtKB; . GO GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB; . GO GO:0043085; P:positive regulation of catalytic activity; IDA:RGD; . GO GO:0045740; P:positive regulation of DNA replication; IDA:RGD; . GO GO:0051260; P:protein homooligomerization; IDA:RGD; . GO GO:0045767; P:regulation of anti-apoptosis; IMP:RGD; . GO GO:0032071; P:regulation of endodeoxyribonuclease activity; ISS:UniProtKB; . GO GO:0060699; P:regulation of endoribonuclease activity; ISS:UniProtKB; . InterPro IPR004301; Nucleoplasmin; . InterPro IPR024057; Nucleoplasmin_core; . Gene3D G3DSA:2.60.120.340; G3DSA:2.60.120.340; 1; . KO K11276; -; . PANTHER PTHR22747; Nucleoplasmin; 1; . Pfam PF03066; Nucleoplasmin; 1; . SUPFAM SSF69203; Nucleoplasmin; 1; . World-2DPAGE Repository (search AC)