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Searching in 'World-2DPAGE Repository [0030]' for entry matching: NPM_RAT




World-2DPAGE Repository (0030):  NPM_RAT

NPM_RAT


General information about the entry
View entry in simple text format
Entry nameNPM_RAT
Primary accession numberP13084
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;.
Gene nameName=Npm1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info 		 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=4.67; Mw=44422  [identification data]
pI=4.70; Mw=44300  [identification data]

IDENTIFICATION: SPOT 1555: Mascot protein score=135. Number of peptides=5 [1]
SPOT 1557: Mascot protein score=109. Number of peptides=4 [1].
MAPPING (identification):
SPOT 1555: Tandem mass spectrometry [1];
SPOT 1557: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtP13084; NPM_RAT.
World-2DPAGE RepositoryP13084; NPM_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameNPM_RAT
Primary accession numberP13084
Secondary accession number(s) Q63698 Q64269
Sequence was last modified on January 1, 1990 (version 1)
Annotations were last modified on November 16, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;
Gene nameName=Npm1
Encoded onName=Npm1
KeywordsAcetylation; ADP-ribosylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disulfide bond; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLJ03969; AAA40796.1; -; mRNA
EMBLM37039; AAA41730.1; -; Genomic_DNA
EMBLM37035; AAA41730.1; JOINED; Genomic_DNA
EMBLM37036; AAA41730.1; JOINED; Genomic_DNA
EMBLM37037; AAA41730.1; JOINED; Genomic_DNA
EMBLM37038; AAA41730.1; JOINED; Genomic_DNA
EMBLM37041; AAA41731.1; -; Genomic_DNA
EMBLM37035; AAA41731.1; JOINED; Genomic_DNA
EMBLM37036; AAA41731.1; JOINED; Genomic_DNA
EMBLM37037; AAA41731.1; JOINED; Genomic_DNA
EMBLM37038; AAA41731.1; JOINED; Genomic_DNA
EMBLM37040; AAA41731.1; JOINED; Genomic_DNA
EMBLM25062; AAA40795.1; -; Genomic_DNA
EMBLJ04943; AAA40794.1; -; mRNA
EMBLJ04944; AAA40793.1; -; Genomic_DNA
EMBLBC060579; AAH60579.1; -; mRNA
EMBLBC088088; AAH88088.1; -; mRNA
IPIIPI00197553; -; .
IPIIPI00230893; -; .
PIRA28939; A28939; .
PIRA36089; A36089; .
PIRB36089; A34168; .
RefSeqNP_037124.1; NM_012992.3; .
UniGeneRn.54537; -; .
ProteinModelPortalP13084; -; .
SMRP13084; 15-118; 241-292; .
STRINGP13084; -; .
PhosphoSiteP13084; -; .
World-2DPAGE0004:P13084; -; .
PRIDEP13084; -; .
EnsemblENSRNOT00000006591; ENSRNOP00000006591; ENSRNOG00000004616; .
EnsemblENSRNOT00000064744; ENSRNOP00000062356; ENSRNOG00000004616; .
GeneID25498; -; .
KEGGrno:25498; -; .
UCSCNM_012992; rat; .
CTD4869; -; .
RGD3192; Npm1; .
eggNOGroNOG11600; -; .
GeneTreeENSGT00440000034554; -; .
HOVERGENHBG001860; -; .
InParanoidP13084; -; .
OMANCFRTED; -; .
OrthoDBEOG4W3SNZ; -; .
PhylomeDBP13084; -; .
NextBio606897; -; .
ArrayExpressP13084; -; .
GenevestigatorP13084; -; .
GermOnlineENSRNOG00000004616; Rattus norvegicus; .
GOGO:0005813; C:centrosome; ISS:UniProtKB; .
GOGO:0005730; C:nucleolus; IDA:RGD; .
GOGO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell; .
GOGO:0003677; F:DNA binding; IDA:RGD; .
GOGO:0019899; F:enzyme binding; IDA:RGD; .
GOGO:0051059; F:NF-kappaB binding; ISS:UniProtKB; .
GOGO:0005547; F:phosphatidylinositol-3; 4; 5-trisphosphate binding
IPI:RGD.
GOGO:0003723; F:RNA binding; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; ISS:UniProtKB; .
GOGO:0007569; P:cell aging; ISS:UniProtKB; .
GOGO:0007098; P:centrosome cycle; ISS:UniProtKB; .
GOGO:0006281; P:DNA repair; ISS:UniProtKB; .
GOGO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB; .
GOGO:0043085; P:positive regulation of catalytic activity; IDA:RGD; .
GOGO:0045740; P:positive regulation of DNA replication; IDA:RGD; .
GOGO:0051260; P:protein homooligomerization; IDA:RGD; .
GOGO:0045767; P:regulation of anti-apoptosis; IMP:RGD; .
GOGO:0032071; P:regulation of endodeoxyribonuclease activity; ISS:UniProtKB; .
GOGO:0060699; P:regulation of endoribonuclease activity; ISS:UniProtKB; .
InterProIPR004301; Nucleoplasmin; .
InterProIPR024057; Nucleoplasmin_core; .
Gene3DG3DSA:2.60.120.340; G3DSA:2.60.120.340; 1; .
KOK11276; -; .
PANTHERPTHR22747; Nucleoplasmin; 1; .
PfamPF03066; Nucleoplasmin; 1; .
SUPFAMSSF69203; Nucleoplasmin; 1; .


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