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Searching in 'World-2DPAGE Repository [0027]' for entry matching: O08553




World-2DPAGE Repository (0027):  O08553


O08553


General information about the entry
View entry in simple text format
Entry nameDPYL2_MOUSE
Primary accession numberO08553
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Dihydropyrimidinase-related protein 2; Short=DRP-2; AltName: Full=Unc-33-like phosphoprotein 2; Short=ULIP-2;.
Gene nameName=Dpysl2
Synonyms=Crmp2, Ulip2
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/prca.201000103;
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GH_4-7 {glomerular protein lysates of a GH-tg animal}
Mus musculus (Mouse)
GH_4-7
  map experimental info
 
GH_4-7

MAP LOCATIONS:
pI=6.00; Mw=63000  [identification data]
pI=6.10; Mw=62000  [identification data]
pI=6.00; Mw=63000  [identification data]

EXPRESSION:
SPOT 8: Avg ratio GH-tg vs. control=-1.59 (p-value=8.5x10-5) [1];
SPOT 9: Avg ratio GH-tg vs. control=-1.51 (p-value=0.0004) [1];
SPOT 11: Avg ratio GH-tg vs. control=-1.52 (p-value=0.0013) [1].

IDENTIFICATION: SPOT 8: SeqCov=50%. Mascot protein score=570 [1]
SPOT 9: SeqCov=58%. Mascot protein score=633 [1]; SPOT 11: SeqCov=54%. Mascot protein score=867 [1].
MAPPING (identification):
SPOT 8: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 9: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 11: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].



GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
GIPRDN_4-7
  map experimental info
 
GIPRDN_4-7

MAP LOCATIONS:
pI=6.23; Mw=63000  [identification data]

EXPRESSION:
SPOT 5: Avg ratio GIPRdn-tg vs. control=-1.51 (p-value=0.0045) [1].

IDENTIFICATION: SPOT 5: SeqCov=45%. Mascot protein score=579 [1].
MAPPING (identification):
SPOT 5: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
Cross-references
REPRODUCTION-2DPAGEIPI00114375; IPI00114375.
REPRODUCTION-2DPAGEO08553; O08553.
UCD-2DPAGEO08553; DPYL2_MOUSE.
UniProtKB/Swiss-ProtO08553; DPYL2_MOUSE.
World-2DPAGE RepositoryO08553; DPYL2_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameDPYL2_MOUSE
Primary accession numberO08553
Secondary accession number(s) Q6P5D0
Sequence was last modified on May 2, 2006 (version 2)
Annotations were last modified on November 16, 2011 (version 104)
Name and origin of the protein
DescriptionRecName: Full=Dihydropyrimidinase-related protein 2; Short=DRP-2; AltName: Full=Unc-33-like phosphoprotein 2; Short=ULIP-2;
Gene nameName=Dpysl2
Synonyms=Crmp2, Ulip2
Encoded onName=Dpysl2; Synonyms=Crmp2, Ulip2
KeywordsComplete proteome; Cytoplasm; Developmental protein; Differentiation; Direct protein sequencing; Neurogenesis; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLY10339; CAA71370.1; -; mRNA
EMBLBC062955; AAH62955.1; -; mRNA
IPIIPI00114375; -; .
RefSeqNP_034085.2; NM_009955.3; .
UniGeneMm.352648; -; .
UniGeneMm.475100; -; .
ProteinModelPortalO08553; -; .
SMRO08553; 14-490; .
IntActO08553; 5; .
STRINGO08553; -; .
MEROPSM38.975; -; .
PhosphoSiteO08553; -; .
REPRODUCTION-2DPAGEIPI00114375; -; .
REPRODUCTION-2DPAGEO08553; -; .
UCD-2DPAGEO08553; -; .
PRIDEO08553; -; .
EnsemblENSMUST00000022629; ENSMUSP00000022629; ENSMUSG00000022048; .
GeneID12934; -; .
KEGGmmu:12934; -; .
UCSCuc007uko.1; mouse; .
CTD1808; -; .
MGIMGI:1349763; Dpysl2; .
eggNOGmaNOG14228; -; .
GeneTreeENSGT00550000074371; -; .
HOGENOMHBG724623; -; .
HOVERGENHBG000806; -; .
InParanoidO08553; -; .
OMATEWHKGV; -; .
OrthoDBEOG48PMJT; -; .
PhylomeDBO08553; -; .
NextBio282608; -; .
ArrayExpressO08553; -; .
BgeeO08553; -; .
CleanExMM_DPYSL2; -; .
GenevestigatorO08553; -; .
GermOnlineENSMUSG00000022048; Mus musculus; .
GOGO:0030425; C:dendrite; IDA:MGI; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0043025; C:neuronal cell body; IDA:MGI; .
GOGO:0016812; F:hydrolase activity; acting on carbon-nitrogen (but not peptide) bonds; in cyclic amides
IEA:InterPro.
GOGO:0006208; P:pyrimidine base catabolic process; IEA:InterPro; .
InterProIPR006680; Amidohydro_1; .
InterProIPR011778; Hydantoinase/dihydroPyrase; .
InterProIPR011059; Metal-dep_hydrolase_composite; .
KOK07528; -; .
PfamPF01979; Amidohydro_1; 1; .
SUPFAMSSF51338; Metalo_hydrolase; 2; .
TIGRFAMsTIGR02033; D-hydantoinase; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server