World-2DPAGE Repository

O08553:

ID   DPYL2_MOUSE;
AC   O08553;
DT   30-Sep-2010, integrated into [0027] - Glomerular proteome of murine
DT   nephropathy models at onset of albuminuria (release 1).
DT   21-Jun-2011, 2D annotation version 2.
DT   23-Nov-2011, general annotation version 2.
DE   RecName: Full=Dihydropyrimidinase-related protein 2; Short=DRP-2;
DE   AltName: Full=Unc-33-like phosphoprotein 2; Short=ULIP-2;.
GN   Name=Dpysl2; Synonyms=Crmp2, Ulip2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
IM   GH_4-7, GIPRDN_4-7.
RN   [1]
RP   2D-PAGE GEL CHARACTERIZATION.
RX   DOI=10.1002/prca.201000103;
RA   Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich
RA   T., Arnold G.J., Wanke R.;
RT   ''Differential glomerular proteome analysis of two murine nephropathy
RT   models at onset of albuminuria'';
RL   Proteomics - Clinical Applications 5(6):375-381 (2011).
2D   -!- MASTER: GH_4-7;
2D   -!-   PI/MW: SPOT 8=6.00/63000;
2D   -!-   PI/MW: SPOT 9=6.10/62000;
2D   -!-   PI/MW: SPOT 11=6.00/63000;
2D   -!-   EXPRESSION: SPOT 8: Avg ratio GH-tg vs. control=-1.59
2D         (p-value=8.5x10-5) [1]; SPOT 9: Avg ratio GH-tg vs. control=-1.51
2D         (p-value=0.0004) [1]; SPOT 11: Avg ratio GH-tg vs. control=-1.52
2D         (p-value=0.0013) [1].
2D   -!-   IDENTIFICATION: SPOT 8: SeqCov=50%. Mascot protein score=570 [1];
2D         SPOT 9: SeqCov=58%. Mascot protein score=633 [1]; SPOT 11: SeqCov=54%.
2D         Mascot protein score=867 [1].
2D   -!-   MAPPING: SPOT 8: Peptide mass fingerprinting [1]; SPOT 8: Tandem
2D         mass spectrometry [1]; SPOT 9: Peptide mass fingerprinting [1]; SPOT 9:
2D         Tandem mass spectrometry [1]; SPOT 11: Peptide mass fingerprinting [1];
2D         SPOT 11: Tandem mass spectrometry [1].
2D   -!- MASTER: GIPRDN_4-7;
2D   -!-   PI/MW: SPOT 5=6.23/63000;
2D   -!-   EXPRESSION: SPOT 5: Avg ratio GIPRdn-tg vs. control=-1.51
2D         (p-value=0.0045) [1].
2D   -!-   IDENTIFICATION: SPOT 5: SeqCov=45%. Mascot protein score=579 [1].
2D   -!-   MAPPING: SPOT 5: Peptide mass fingerprinting [1]; SPOT 5: Tandem
2D         mass spectrometry [1].
CC   ---------------------------------------------------------------------------
CC   Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
CC   ---------------------------------------------------------------------------
DR   REPRODUCTION-2DPAGE; IPI00114375; IPI00114375.
DR   REPRODUCTION-2DPAGE; O08553; O08553.
DR   UCD-2DPAGE; O08553; DPYL2_MOUSE.
DR   UniProtKB/Swiss-Prot; O08553; DPYL2_MOUSE.
DR   World-2DPAGE Repository; O08553; DPYL2_MOUSE.
//

The following 2-D maps are available for this protein:

	glomerular protein lysates of a GH-tg animal	glomerular protein lysates of a GIPRdn-tg animal

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